Q06086 (TYDC2_PETCR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Tyrosine decarboxylase 2
EC=4.1.1.25

Gene names

Name:

TYRDC-2

Organism

Petroselinum crispum (Parsley) (Petroselinum hortense)

Taxonomic identifier

4043 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Apiales › Apiineae › Apiaceae › Apioideae › apioid superclade › Apieae › Petroselinum

Protein attributes

Sequence length	514 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	L-tyrosine = tyramine + CO2.
Cofactor	Pyridoxal phosphate.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the group II decarboxylase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Decarboxylase Lyase
Gene Ontology (GO)
Biological_process	cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro tyrosine decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 514	514	Tyrosine decarboxylase 2		PRO_0000146996
Amino acid modifications
	Modified residue	317	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q06086 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: B742FB7CABB4CF39	FASTA	514	57,450
	10 20 30 40 50 60 MGSIDNLTEK LASQFPMNTL EPEEFRRQGH MMIDFLADYY RKVENYPVRS QVSPGYLREI 70 80 90 100 110 120 LPESAPYNPE SLETILQDVQ TKIIPGITHW QSPNFFAYFP SSGSTAGFLG EMLSTGFNVV 130 140 150 160 170 180 GFNWMVSPAA TELENVVTDW FGKMLQLPKS FLFSGGGGGV LQGTTCEAIL CTLVAARDKN 190 200 210 220 230 240 LRQHGMDNIG KLVVYCSDQT HSALQKAAKI AGIDPKNFRA IETTKSSNFQ LCPKRLESAI 250 260 270 280 290 300 LHDLQNGLIP LYLCATVGTT SSTTVDPLPA LTEVAKKYDL WVHVDAAYAG SACICPEFRQ 310 320 330 340 350 360 YLDGVENADS FSLNAHKWFL TTLDCCCLWV RNPSALIKSL STYPEFLKNN ASETNKVVDY 370 380 390 400 410 420 KDWQIMLSRR FRALKLWFVL RSYGVGQLRE FIRGHVGMAK YFEGLVNMDK RFEVVAPRLF 430 440 450 460 470 480 SMVCFRIKPS AMIGKNDEDE VNEINRKLLE SVNDSGRIYV SHTVLGGIYV IRFAIGGTLT 490 500 510 DINHVSAAWK VLQDHAGALL DDTFTSNKLV EVLS

References

[1]	"A pathogen-responsive gene of parsley encodes tyrosine decarboxylase." Kawalleck P., Keller H., Hahlbrock K., Scheel D., Somssich I.E. J. Biol. Chem. 268:2189-2194(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M96070 mRNA. Translation: AAA33860.1.
PIR	A44405.
3D structure databases
ProteinModelPortal	Q06086.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.40.640.10. 1 hit. 3.90.1150.10. 1 hit.
InterPro	IPR010977. Aromatic_deC. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. IPR021115. Pyridoxal-P_BS. [Graphical view]
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
PRINTS	PR00800. YHDCRBOXLASE.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITE	PS00392. DDC_GAD_HDC_YDC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TYDC2_PETCR

Accession

Primary (citable) accession number: Q06086

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	April 3, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program