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Protein

Factor arrest protein 10

Gene

FAR10

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Participates in the control of the reentry into the cell cycle following pheromone treatment.1 Publication

GO - Biological processi

  • re-entry into mitotic cell cycle after pheromone arrest Source: SGD

Keywordsi

Biological processCell cycle

Enzyme and pathway databases

BioCyciYEAST:G3O-32347-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Factor arrest protein 10
Gene namesi
Name:FAR10
Ordered Locus Names:YLR238W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLR238W
SGDiS000004228 FAR10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 454CytoplasmicSequence analysisAdd BLAST454
Transmembranei455 – 475Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST21
Topological domaini476 – 478ExtracellularSequence analysis3

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000871891 – 478Factor arrest protein 10Add BLAST478

Proteomic databases

MaxQBiQ06001
PaxDbiQ06001
PRIDEiQ06001

PTM databases

iPTMnetiQ06001

Interactioni

Subunit structurei

Component of a complex at least composed of FAR3, FAR7, FAR8, FAR10, FAR11 and VPS64.

Protein-protein interaction databases

BioGridi31505, 212 interactors
DIPiDIP-1572N
IntActiQ06001, 12 interactors
MINTiQ06001
STRINGi4932.YLR238W

Structurei

3D structure databases

ProteinModelPortaliQ06001
SMRiQ06001
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini116 – 176FHAPROSITE-ProRule annotationAdd BLAST61

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili342 – 426Sequence analysisAdd BLAST85

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi108 – 115Poly-Ser8

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00530000068298
HOGENOMiHOG000065944
InParanoidiQ06001
OMAiKPDITNG
OrthoDBiEOG092C44DL

Family and domain databases

CDDicd00060 FHA, 1 hit
InterProiView protein in InterPro
IPR000253 FHA_dom
IPR008984 SMAD_FHA_dom_sf
PfamiView protein in Pfam
PF00498 FHA, 1 hit
SMARTiView protein in SMART
SM00240 FHA, 1 hit
SUPFAMiSSF49879 SSF49879, 2 hits
PROSITEiView protein in PROSITE
PS50006 FHA_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q06001-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGPGPEINK EEHPSSPGKK QITYNSIPKN ANLIDGSTNS SKRPIEKYDK
60 70 80 90 100
RIADPTKSYF PHSISRTPRR KYTYILVLTS LNGTFESKHV VIPFKPDGLK
110 120 130 140 150
LGRPVANSNS SSSSSLRGGK RVDSHTFSQV RSDNGNFDSR VLSRNHALLS
160 170 180 190 200
CDPLTGKVYI RDLKSSNGTF INGQRIGSND VEIKVGDVID LGTDIDTKIE
210 220 230 240 250
HRKISATVEE LFVQPLLESP IFENEDSDDC HTITEKEEAA AITSHIYGDS
260 270 280 290 300
NNLELEEVIL GSDTEILSGI FINNCIGTSP TLSNIIKTLA MEIPFSKCDN
310 320 330 340 350
FKLQSMENFL INYTTHLEYT NKLLVEKNDQ QLVKLQNGLR RKLSGKYEKI
360 370 380 390 400
IEQNRNQVKQ LERDHMFFKK SFEVKKRRNN EKQKSMEREI EDLKTRLEVE
410 420 430 440 450
RYKNSQMMKK NKQKEQELST ASKKKTTEHD TRGVPGMNPK GTDKFSIKNT
460 470
LCNHFTLLTF GTISIGIIAI VFKILSPN
Length:478
Mass (Da):54,092
Last modified:November 1, 1996 - v1
Checksum:iA3A4B2B83C967DD0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U19027 Genomic DNA Translation: AAB67404.1
BK006945 Genomic DNA Translation: DAA09552.1
PIRiS51457
RefSeqiNP_013339.1, NM_001182125.1

Genome annotation databases

EnsemblFungiiYLR238W; YLR238W; YLR238W
GeneIDi850939
KEGGisce:YLR238W

Similar proteinsi

Entry informationi

Entry nameiFAR10_YEAST
AccessioniPrimary (citable) accession number: Q06001
Secondary accession number(s): D6VYN6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health