ID   ABAH1_ORYSJ             Reviewed;         471 AA.
AC   Q05JG2; Q6YVJ4;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   24-MAR-2009, entry version 24.
DE   RecName: Full=Abscisic acid 8'-hydroxylase 1;
DE            Short=ABA 8'-hydroxylase 1;
DE            EC=1.14.13.93;
DE   AltName: Full=OsABA8ox1;
DE   AltName: Full=Cytochrome P450 707A5;
GN   Name=CYP707A5; Synonyms=ABA8OX1;
GN   OrderedLocusNames=Os02g0703600, LOC_Os02g47470;
GN   ORFNames=OJ1218_D07.28, P0724B10.17, OsJ_007800;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade;
OC   Ehrhartoideae; Oryzeae; Oryza.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, AND INDUCTION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=17205969; DOI=10.1093/pcp/pcm003;
RA   Saika H., Okamoto M., Miyoshi K., Kushiro T., Shinoda S., Jikumaru Y.,
RA   Fujimoto M., Arikawa T., Takahashi H., Ando M., Arimura S., Miyao A.,
RA   Hirochika H., Kamiya Y., Tsutsumi N., Nambara E., Nakazono M.;
RT   "Ethylene promotes submergence-induced expression of OsABA8ox1, a gene
RT   that encodes ABA 8'-hydroxylase in rice.";
RL   Plant Cell Physiol. 48:287-298(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=17210932; DOI=10.1101/gr.5509507;
RG   The rice annotation project (RAP);
RT   "Curated genome annotation of Oryza sativa ssp. japonica and
RT   comparative genome analysis with Arabidopsis thaliana.";
RL   Genome Res. 17:175-183(2007).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H.,
RA   Cong L., Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J.,
RA   Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X.,
RA   Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y.,
RA   Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J.,
RA   Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y.,
RA   Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y.,
RA   Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z.,
RA   Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T.,
RA   Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H.,
RA   Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
RA   Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
RA   Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J.,
RA   Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Involved in the oxidative degradation of abscisic acid.
CC   -!- CATALYTIC ACTIVITY: (+)-abscisate + NADPH + O(2) = 8'-
CC       hydroxyabscisate + NADP(+) + H(2)O.
CC   -!- COFACTOR: Heme group (By similarity).
CC   -!- PATHWAY: Plant hormone degradation; abscisic acid degradation.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass
CC       membrane protein.
CC   -!- INDUCTION: By ethylene treatment and by flooding.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAD07562.1; Type=Erroneous gene model prediction;
CC       Sequence=BAD08071.1; Type=Erroneous gene model prediction;
CC       Sequence=BAF09769.1; Type=Erroneous gene model prediction;
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DR   EMBL; AB277270; BAF34848.1; -; mRNA.
DR   EMBL; AP004052; BAD07562.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP005825; BAD08071.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008208; BAF09769.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CM000139; EAZ24317.1; -; Genomic_DNA.
DR   RefSeq; NP_001047855.1; -.
DR   UniGene; Os.12145; -.
DR   GeneID; 4330448; -.
DR   KEGG; osa:4330448; -.
DR   Gramene; Q6YVJ4; -.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IEA:EC.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017973; Cyt_P450_C.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   Gene3D; G3DSA:1.10.630.10; Cyt_P450; 1.
DR   PANTHER; PTHR19383; Cyt_P450; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Heme; Iron; Membrane; Metal-binding;
KW   Monooxygenase; NADP; Oxidoreductase; Stress response; Transmembrane.
FT   CHAIN         1    471       Abscisic acid 8'-hydroxylase 1.
FT                                /FTId=PRO_0000288644.
FT   TRANSMEM      1     21       Potential.
FT   METAL       415    415       Iron (heme axial ligand) (By similarity).
SQ   SEQUENCE   471 AA;  52920 MW;  24D4FB1BC5A62BE9 CRC64;
     MGAFLLFVCV LAPFLLVCAV RGRRRQAGSS EAAACGLPLP PGSMGWPYVG ETFQLYSSKN
     PNVFFNKKRN KYGPIFKTHI LGCPCVMVSS PEAARFVLVT QAHLFKPTFP ASKERMLGPQ
     AIFFQQGDYH AHLRRIVSRA FSPESIRASV PAIEAIALRS LHSWDGQFVN TFQEMKTYAL
     NVALLSIFGE EEMRYIEELK QCYLTLEKGY NSMPVNLPGT LFHKAMKARK RLGAIVAHII
     SARRERQRGN DLLGSFVDGR EALTDAQIAD NVIGVIFAAR DTTASVLTWM VKFLGDHPAV
     LKAVTEEQLQ IAKEKEASGE PLSWADTRRM KMTSRVIQET MRVASILSFT FREAVEDVEY
     QGYLIPKGWK VLPLFRNIHH NPDHFPCPEK FDPSRFEVAP KPNTFMPFGN GTHSCPGNEL
     AKLEMLVLFH HLATKYRWST SKSESGVQFG PFALPLNGLP MSFTRKNTEQ E
//