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Q05FI3 (EFTU_CARRP) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu

Short name=EF-Tu
Gene names
Name:tuf
Ordered Locus Names:CRP_157
OrganismCarsonella ruddii (strain PV) [Complete proteome] [HAMAP]
Taxonomic identifier387662 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHalomonadaceaeZymobacter groupCandidatus Carsonella

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Elongation factor Tu HAMAP-Rule MF_00118
PRO_1000015632

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding81 – 855GTP By similarity
Nucleotide binding136 – 1394GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q05FI3 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 25D0F1160D6350D3

FASTA39844,125
        10         20         30         40         50         60 
MAKKKFNREK IHLNVGTIGH VDHGKTTLTA ALTKVSSDLY GSECRPFDSI DNAPEERERG 

        70         80         90        100        110        120 
ITISTSHVEY ESETKHYAHV DCPGHADYIK NMITGAAQMD GAILVCSAVD GPMPQTREHI 

       130        140        150        160        170        180 
LLARQVGVPT IIVYLNKADC VKDKELLELV EMEIRELLTE YDFDGNNTKI IIGSALLALE 

       190        200        210        220        230        240 
NKDDNQLGTS SIIKLLEILD KNIPVPNRII DKPFLMPIED VFSISGRGTV VTGKIERGII 

       250        260        270        280        290        300 
KTGEEIEIVG FKETIKTIVI GIEMFKKTLD EGFAGENVGI LLRSIKREEV ERGQVLIKSG 

       310        320        330        340        350        360 
TIKPHTNFIC EVYILSKEEG GRHTPFFKGY KPQFYFRTTD ITGICDLPKN IEMVMPGDNV 

       370        380        390 
KLIVKLLSSI AIEKGLRFAI REGGKTVGAG IITEVLND 

« Hide

References

[1]"The 160-kilobase genome of the bacterial endosymbiont Carsonella."
Nakabachi A., Yamashita A., Toh H., Ishikawa H., Dunbar H.E., Moran N.A., Hattori M.
Science 314:267-267(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PV.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009180 Genomic DNA. Translation: BAF35188.1.
RefSeqYP_802554.1. NC_008512.1.

3D structure databases

ProteinModelPortalQ05FI3.
SMRQ05FI3. Positions 2-397.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING387662.CRP_157.

Proteomic databases

PRIDEQ05FI3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAF35188; BAF35188; CRP_157.
GeneID4414873.
KEGGcrp:CRP_157.
PATRIC31966620. VBICanCar121052_0155.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMAGTEMCMP.
OrthoDBEOG6R5C6X.

Enzyme and pathway databases

BioCycCCAR387662:GBZ4-185-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_CARRP
AccessionPrimary (citable) accession number: Q05FI3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: July 9, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families