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Q05DS6

- Q05DS6_HUMAN

UniProt

Q05DS6 - Q05DS6_HUMAN

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Protein
Submitted name:

PIAS4 protein

Gene
PIAS4
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: Ensembl
  2. SUMO ligase activity Source: Ensembl
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. negative regulation of NF-kappaB transcription factor activity Source: Ensembl
  2. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
  3. positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
  4. positive regulation of keratinocyte apoptotic process Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
PIAS4 proteinImported
Gene namesi
Name:PIAS4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. nuclear matrix Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ05DS6.
BgeeiQ05DS6.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG082394.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR023321. PINIT.
IPR004181. Znf_MIZ.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF02891. zf-MIZ. 1 hit.
[Graphical view]
PROSITEiPS51466. PINIT. 1 hit.
PS51044. ZF_SP_RING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q05DS6-1 [UniParc]FASTAAdd to Basket

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MYLSSATNRI TVTWGNYGKS YSVALYLVRQ LTSSELLQRL KTIGVKHPEL    50
CKALVKEKLR LDPDSEIATT GVRVSLICPL VKMRLSVPCR AETCAHLQCF 100
DAVFYLQMNE KKPTWMCPVC DKPAPYDQLI IDGLLSKILS ECEDADEIEY 150
LVDGSWCPIR AEKERSCSPQ GAILVLGPSD ANGLLPAPSV NGSGALGSTG 200
GGGPVGSMEN GKPGADVVDL TLDSSSSSED EEEEEEEEED EDEEGPRPKR 250
RCPFQKGLVP AC 262
Length:262
Mass (Da):28,485
Last modified:November 14, 2006 - v1
Checksum:i4183EC5A7D162293
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC004389 mRNA. Translation: AAH04389.1.
UniGeneiHs.105779.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC004389 mRNA. Translation: AAH04389.1 .
UniGenei Hs.105779.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG082394.

Miscellaneous databases

ChiTaRSi PIAS4. human.

Gene expression databases

ArrayExpressi Q05DS6.
Bgeei Q05DS6.

Family and domain databases

Gene3Di 3.30.40.10. 1 hit.
InterProi IPR023321. PINIT.
IPR004181. Znf_MIZ.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF02891. zf-MIZ. 1 hit.
[Graphical view ]
PROSITEi PS51466. PINIT. 1 hit.
PS51044. ZF_SP_RING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PancreasImported.

Entry informationi

Entry nameiQ05DS6_HUMAN
AccessioniPrimary (citable) accession number: Q05DS6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: May 14, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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