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Q05DS6

- Q05DS6_HUMAN

UniProt

Q05DS6 - Q05DS6_HUMAN

Protein
Submitted name:

PIAS4 protein

Gene

PIAS4

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (14 Nov 2006)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: Ensembl
    2. SUMO ligase activity Source: Ensembl
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. negative regulation of NF-kappaB transcription factor activity Source: Ensembl
    2. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
    3. positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
    4. positive regulation of keratinocyte apoptotic process Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    PIAS4 proteinImported
    Gene namesi
    Name:PIAS4Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. nuclear matrix Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ05DS6.
    BgeeiQ05DS6.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG082394.

    Family and domain databases

    Gene3Di3.30.40.10. 1 hit.
    InterProiIPR023321. PINIT.
    IPR004181. Znf_MIZ.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view]
    PfamiPF02891. zf-MIZ. 1 hit.
    [Graphical view]
    PROSITEiPS51466. PINIT. 1 hit.
    PS51044. ZF_SP_RING. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q05DS6-1 [UniParc]FASTAAdd to Basket

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    MYLSSATNRI TVTWGNYGKS YSVALYLVRQ LTSSELLQRL KTIGVKHPEL    50
    CKALVKEKLR LDPDSEIATT GVRVSLICPL VKMRLSVPCR AETCAHLQCF 100
    DAVFYLQMNE KKPTWMCPVC DKPAPYDQLI IDGLLSKILS ECEDADEIEY 150
    LVDGSWCPIR AEKERSCSPQ GAILVLGPSD ANGLLPAPSV NGSGALGSTG 200
    GGGPVGSMEN GKPGADVVDL TLDSSSSSED EEEEEEEEED EDEEGPRPKR 250
    RCPFQKGLVP AC 262
    Length:262
    Mass (Da):28,485
    Last modified:November 14, 2006 - v1
    Checksum:i4183EC5A7D162293
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC004389 mRNA. Translation: AAH04389.1.
    UniGeneiHs.105779.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC004389 mRNA. Translation: AAH04389.1 .
    UniGenei Hs.105779.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG082394.

    Miscellaneous databases

    ChiTaRSi PIAS4. human.

    Gene expression databases

    ArrayExpressi Q05DS6.
    Bgeei Q05DS6.

    Family and domain databases

    Gene3Di 3.30.40.10. 1 hit.
    InterProi IPR023321. PINIT.
    IPR004181. Znf_MIZ.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view ]
    Pfami PF02891. zf-MIZ. 1 hit.
    [Graphical view ]
    PROSITEi PS51466. PINIT. 1 hit.
    PS51044. ZF_SP_RING. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: PancreasImported.

    Entry informationi

    Entry nameiQ05DS6_HUMAN
    AccessioniPrimary (citable) accession number: Q05DS6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 14, 2006
    Last sequence update: November 14, 2006
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.