Ikbkb protein - Mus musculus (Mouse)

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Unreviewed, UniProtKB/TrEMBL Q05DR8 (Q05DR8_MOUSE)

Last modified January 19, 2010. Version 24. History...

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Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
Ikbkb protein EMBL AAH04772.1

Gene names

Name:

Ikbkb MGI 1338071

Organism

Mus musculus (Mouse) EMBL AAH04772.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	707 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	I-kappaB phosphorylation Inferred from electronic annotation. Source: Compara positive regulation of NF-kappaB transcription factor activity Inferred from electronic annotation. Source: Compara regulation of I-kappaB kinase/NF-kappaB cascade Inferred from electronic annotation. Source: Compara response to drug Inferred from electronic annotation. Source: Compara response to toxin Inferred from electronic annotation. Source: Compara skeletal muscle contraction Inferred from electronic annotation. Source: Compara
Cellular component	IkappaB kinase complex Inferred from electronic annotation. Source: Compara microsome Inferred from electronic annotation. Source: Compara
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro identical protein binding Inferred from electronic annotation. Source: Compara protein heterodimerization activity Inferred from electronic annotation. Source: Compara protein serine/threonine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Experimental info

Non-terminal residue

1

EMBL AAH04772.1

Sequences

Sequence

Length

Mass (Da)

Tools

Q05DR8-1 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 84C4FE7B8991B98A
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707

81,055

        10         20         30         40         50         60 
MSWSPSLPTQ TCGAWEMKER LGTGGFGNVI RWHNQATGEQ IAIKQCRQEL SPKNRDRWCL 

        70         80         90        100        110        120 
EIQIMRRLNH PNVVAARDVP EGMQNLAPND LPLLAMEYCQ GGDLRRYLNQ FENCCGLREG 

       130        140        150        160        170        180 
AVLTLLSDIA SALRYLHENR IIHRDLKPEN IVLQQGEKRL IHKIIDLGYA KELDQGSLCT 

       190        200        210        220        230        240 
SFVGTLQYLA PELLEQQKYT VTVDYWSFGT LAFECITGFR PFLPNWQPVQ WHSKVRQKSE 

       250        260        270        280        290        300 
VDIVVSEDLN GAVKFSSSLP FPNNLNSVLA ERLEKWLQLM LMWHPRQRGT DPQYGPNGCF 

       310        320        330        340        350        360 
RALDDILNLK LVHVLNMVTG TVHTYPVTED ESLQSLKTRI QEDTGILETD QELLQEAGLV 

       370        380        390        400        410        420 
LLPDKPATQC ISDSKTNEGL TLDMDLVFLF DNSKINYETQ ITPRPQPESV SCILQEPKRN 

       430        440        450        460        470        480 
LSFFQLRKVW GQVWHSIQTL KEDCNRLQQG QRAAMMSLLR NNSCLSKMKN AMASTAQQLK 

       490        500        510        520        530        540 
AKLDFFKTSI QIDLEKYKEQ TEFGITSDKL LLAWREMEQA VEQCGRENDV KHLVERMMAL 

       550        560        570        580        590        600 
QTDIVDLQRS PMGRKQGGTL DDLEEQAREL YRRLREKPRD QRTEGDSQEM VRLLLQAIQS 

       610        620        630        640        650        660 
FEKKVRVIYT QLSKTVVCKQ KALELLPKVE EVVSLMNEDE RTVVRLQEKR QKELWNLLKI 

       670        680        690        700 
ACSKVRGPVS GSPDSMNVSR LSHPGQLMSQ PSSACDSLPE SDKKKKK

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: NMRI EMBL AAH04772.1. Tissue: Mammary tumor. WAP-Tag model. 5 months old EMBL AAH04772.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC004772 mRNA. Translation: AAH04772.1.
IPI	IPI00930842.
UniGene	Mm.277886
3D structure databases
SMR	Q05DR8. Positions 14-293.
ModBase	Search...
Protein-protein interaction databases
STRING	Q05DR8.
Genome annotation databases
Ensembl	ENSMUST00000033939; ENSMUSP00000033939; ENSMUSG00000031537; Mus musculus. [Genome view] ENSMUST00000063401; ENSMUSP00000064235; ENSMUSG00000031537; Mus musculus. [Genome view]
UCSC	uc009ldo.1. mouse.
Organism-specific databases
MGI	MGI:1338071. Ikbkb.
Phylogenomic databases
HOVERGEN	Q05DR8.
InParanoid	Q05DR8.
Gene expression databases
ArrayExpress	Q05DR8.
Bgee	Q05DR8.
Genevestigator	Q05DR8.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017442. Se/Thr_prot_kinase-like_dom. IPR008271. Ser/Thr_prot_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
PROSITE	PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q05DR8_MOUSE

Accession

Primary (citable) accession number: Q05DR8

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	January 19, 2010
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information