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Protein

Protein FAM160A1

Gene

FAM160A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM160A1
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:34237. FAM160A1.

Pathology & Biotechi

Organism-specific databases

DisGeNETi729830.
OpenTargetsiENSG00000164142.
PharmGKBiPA162386739.

Polymorphism and mutation databases

BioMutaiFAM160A1.
DMDMi189042274.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003195781 – 1040Protein FAM160A1Add BLAST1040

Proteomic databases

EPDiQ05DH4.
MaxQBiQ05DH4.
PaxDbiQ05DH4.
PeptideAtlasiQ05DH4.
PRIDEiQ05DH4.

PTM databases

iPTMnetiQ05DH4.
PhosphoSitePlusiQ05DH4.

Expressioni

Gene expression databases

BgeeiENSG00000164142.
CleanExiHS_FAM160A1.
ExpressionAtlasiQ05DH4. baseline and differential.
GenevisibleiQ05DH4. HS.

Organism-specific databases

HPAiHPA046348.

Interactioni

Protein-protein interaction databases

BioGridi610225. 2 interactors.

Structurei

3D structure databases

ProteinModelPortaliQ05DH4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi690 – 808Glu-richAdd BLAST119

Sequence similaritiesi

Belongs to the UPF0518 family.Curated

Phylogenomic databases

eggNOGiKOG3695. Eukaryota.
ENOG410XY4X. LUCA.
GeneTreeiENSGT00760000119270.
HOGENOMiHOG000112444.
HOVERGENiHBG107874.
InParanoidiQ05DH4.
OMAiSACIVEY.
OrthoDBiEOG091G0189.
PhylomeDBiQ05DH4.
TreeFamiTF313941.

Family and domain databases

InterProiView protein in InterPro
IPR019384. RetinoicA-induced_16-like.
PfamiView protein in Pfam
PF10257. RAI16-like. 1 hit.

Sequencei

Sequence statusi: Complete.

Q05DH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSSVSTESK LQQAVSLQGV DPETCMIVFK NHWAQVVKIL EKHDPLKNTQ
60 70 80 90 100
AKYGSIPPDE ASAVQNYVEH MLFLLIEEQA KDAAMGPILE FVVSENIMEK
110 120 130 140 150
LFLWSLRREF TDETKIEQLK MYEMLVTQSH QPLLHHKPIL KPLMMLLSSC
160 170 180 190 200
SGTTTPTVEE KLVVLLNQLC SILAKDPSIL ELFFHTSEDQ GAANFLIFSL
210 220 230 240 250
LIPFIHREGS VGQQARDALL FIMSLSAENT MVAHHIVENT YFCPVLATGL
260 270 280 290 300
SGLYSSLPTK LEEKGEEWHC LLKDDWLLLP SLVQFMNSLE FCNAVIQVAH
310 320 330 340 350
PLIRNQLVNY IYNGFLVPVL APALHKVTVE EVMTTTAYLD LFLRSISEPA
360 370 380 390 400
LLEIFLRFIL LHQHENVHIL DTLTSRINTP FRLCVVSLAL FRTLIGLHCE
410 420 430 440 450
DVMLQLVLRY LIPCNHMMLS QRWAVKERDC YSVSAAKLLA LTPVCCSSGI
460 470 480 490 500
TLTLGNQERD YILWSKCMHD TSGPVERPFP EAFSESACIV EYGKALDISY
510 520 530 540 550
LQYLWEAHTN ILRCMRDCRV WSALYDGDSP DPEMFLQSLT EEGSVSSACP
560 570 580 590 600
VFGLPQQLPR KTGPQLAPRK DKSQTELEWD DSYDTGISSG ADVGSPGPYD
610 620 630 640 650
DLEVSGPPAP IDPPKHIQEM KKNALLLFKG SYIEESDFQD DVMVYRLCAE
660 670 680 690 700
KDSEDMKDSQ EEAARPPAEA QAEVQSVPIN NGPLLSTQPE TDSEEEWNRD
710 720 730 740 750
NSDPFHSEPK EPKQEREPEA APESNSELAS PAPEAEHSSN LTAAHPESEE
760 770 780 790 800
LIAQYDQIIK ELDSGAEGLM EQNYPTPDPL LLTKEEEGKE ESKGEKEKEG
810 820 830 840 850
KKELEDEEDD FDSFIAEMPA VETVPSPFVG RDEAAFASRH PVRTQSTPFT
860 870 880 890 900
GPFISVVLSK LENMLENSLH VNLLLIGIIT QLASYPQPLL RSFLLNTNMV
910 920 930 940 950
FQPSVRSLYQ VLASVKNKIE QFASVERDFP GLLIQAQQYL LFRVDMSDMT
960 970 980 990 1000
PAALTKDPIQ EASRTGSGKN LLDGPPRVLQ PFLTHRTKVA EAPPNLPLPV
1010 1020 1030 1040
RNPMLAAALF PEFLKELAAL AQEHSILCYK ILGDFEDSCC
Length:1,040
Mass (Da):116,621
Last modified:February 26, 2008 - v2
Checksum:i1B7A936DB0CAAFBD
GO

Sequence cautioni

The sequence AAH14937 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAH14937 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAC86147 differs from that shown. Aberrant splicing.Curated
The sequence BAC86147 differs from that shown. Reason: Frameshift at positions 859 and 986.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092611 Genomic DNA. No translation available.
AC097455 Genomic DNA. No translation available.
AK125363 mRNA. Translation: BAC86147.1. Sequence problems.
BC014937 mRNA. Translation: AAH14937.1. Sequence problems.
CCDSiCCDS47146.1.
RefSeqiNP_001103447.1. NM_001109977.2.
NP_001335623.1. NM_001348694.1.
XP_005263256.1. XM_005263199.1.
XP_011530522.1. XM_011532220.1.
XP_011530523.1. XM_011532221.2.
XP_011530525.1. XM_011532223.2.
XP_011530526.1. XM_011532224.2.
UniGeneiHs.633810.

Genome annotation databases

EnsembliENST00000435205; ENSP00000413196; ENSG00000164142.
ENST00000505231; ENSP00000421580; ENSG00000164142.
GeneIDi729830.
KEGGihsa:729830.
UCSCiuc003imj.2. human.

Similar proteinsi

Entry informationi

Entry nameiF16A1_HUMAN
AccessioniPrimary (citable) accession number: Q05DH4
Secondary accession number(s): Q6ZUS2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: July 5, 2017
This is version 76 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries