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Protein
Submitted name:

UACA protein

Gene

UACA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
UACA proteinImported
Gene namesi
Name:UACAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38062.

PTM / Processingi

Proteomic databases

PaxDbiQ05DB3.
PRIDEiQ05DB3.

Expressioni

Gene expression databases

GenevisibleiQ05DB3. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000314556.

Structurei

3D structure databases

ProteinModelPortaliQ05DB3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 251227ANK_REP_REGIONInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili276 – 31035Sequence analysisAdd
BLAST
Coiled coili318 – 35942Sequence analysisAdd
BLAST
Coiled coili465 – 49935Sequence analysisAdd
BLAST
Coiled coili526 – 55328Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains 5 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotation, Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IJC6. Eukaryota.
COG0666. LUCA.
HOGENOMiHOG000147885.
HOVERGENiHBG066395.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR030227. UACA.
[Graphical view]
PANTHERiPTHR24173:SF23. PTHR24173:SF23. 2 hits.
PfamiPF12796. Ank_2. 2 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q05DB3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMNCWFSCTP KNRHAADWNK YDDRLMKAAE RGDVEKVTSI LAKKGVNPGK
60 70 80 90 100
LDVEGRSVFH VVTSKGNLEC LNAILIHGVD ITTSDTAGRN ALHLAAKYGH
110 120 130 140 150
ALCLQKLLQY NCPTEHADLQ GRTALHDAAM ADCPSSIQLL CDHGASVNAK
160 170 180 190 200
DVDGRTPLVL ATQMSRPTIC QLLIDRGADV NSRDKQNRTA LMLGCEYGCR
210 220 230 240 250
DAVEVLIKNG ADISLLDALG HDSSYYARIG DNLDILTLLK TASENTNKGR
260 270 280 290 300
ELWKKGPSLQ QRNLTHMQDE VNVKSHQREH QNIQDLEIEN EDLKERLRKI
310 320 330 340 350
QQEQRILLDK VNGLQLQLNE EVMVADDLES EREKLKSLLA AKEKQHEESL
360 370 380 390 400
RTIEALKNRF KYFESDHLGS GSHFSNRKED MLLKQGQMYM ADSQCTSPGI
410 420 430 440 450
PAHMQSRSML RPLELSLPSQ TSYSENEILK KELEAMRTFC ESAKQDRLKL
460 470 480 490 500
QNELAHKVAE CKALALECER VKEDSDEQIK QLEDALKDVQ KRMYESEGKV
510 520 530 540 550
KQMQTHFLAL KEHLTSEAAS GNHRLTEELK DQLKDLKVKY EGASAEVGKL
560 570 580 590 600
RNQIKQNEMI VEEFKRDEGK LIEENKRLQK ELSMCEMERE KKGRKVTEME
610 620 630
GQAKELSAKL ALSIPAEKFE NMKSSLSNEV NEKAKKKK
Length:638
Mass (Da):72,348
Last modified:November 14, 2006 - v1
Checksum:iF1F28685348F9C7F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei638 – 6381Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC016881 mRNA. Translation: AAH16881.1.
RefSeqiNP_001008225.1. NM_001008224.1.
UniGeneiHs.108049.

Genome annotation databases

GeneIDi55075.
KEGGihsa:55075.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC016881 mRNA. Translation: AAH16881.1.
RefSeqiNP_001008225.1. NM_001008224.1.
UniGeneiHs.108049.

3D structure databases

ProteinModelPortaliQ05DB3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000314556.

Proteomic databases

PaxDbiQ05DB3.
PRIDEiQ05DB3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi55075.
KEGGihsa:55075.

Organism-specific databases

CTDi55075.
PharmGKBiPA38062.

Phylogenomic databases

eggNOGiENOG410IJC6. Eukaryota.
COG0666. LUCA.
HOGENOMiHOG000147885.
HOVERGENiHBG066395.

Miscellaneous databases

ChiTaRSiUACA. human.
GenomeRNAii55075.
NextBioi58608.

Gene expression databases

GenevisibleiQ05DB3. HS.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR030227. UACA.
[Graphical view]
PANTHERiPTHR24173:SF23. PTHR24173:SF23. 2 hits.
PfamiPF12796. Ank_2. 2 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: UterusImported.

Entry informationi

Entry nameiQ05DB3_HUMAN
AccessioniPrimary (citable) accession number: Q05DB3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: April 13, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.