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Protein
Submitted name:

TOPBP1 protein

Gene

TOPBP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

SignaLinkiQ05BV8.

Names & Taxonomyi

Protein namesi
Submitted name:
TOPBP1 proteinImported
Gene namesi
Name:TOPBP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134934073.

PTM / Processingi

Proteomic databases

PaxDbiQ05BV8.
PeptideAtlasiQ05BV8.

Expressioni

Gene expression databases

GenevisibleiQ05BV8. HS.

Structurei

3D structure databases

ProteinModelPortaliQ05BV8.
SMRiQ05BV8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini101 – 172BRCTInterPro annotationAdd BLAST72

Phylogenomic databases

eggNOGiKOG1929. Eukaryota.
ENOG410XPFH. LUCA.
KOiK10728.

Family and domain databases

CDDicd00027. BRCT. 1 hit.
Gene3Di3.40.50.10190. 2 hits.
InterProiView protein in InterPro
IPR001357. BRCT_dom.
PfamiView protein in Pfam
PF00533. BRCT. 1 hit.
SMARTiView protein in SMART
SM00292. BRCT. 1 hit.
SUPFAMiSSF52113. SSF52113. 1 hit.
PROSITEiView protein in PROSITE
PS50172. BRCT. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q05BV8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRNDKEPFF VKFLKSSDNS KCFFKALESI KEFQSEEYLQ IITEEEALKI
60 70 80 90 100
KENDRSLYIC DPFSGVVFDH LKKLGCRIVG PQVVIFCMHH QRCVPRAEHP
110 120 130 140 150
VYNMVMSDVT ISCTSLEKEK REEVHKYVQM MGGRVYRDLN VSVTHLIAGE
160 170 180
VGSKKYLVAA NLKKPILLPS WIKTLWEKSQ KKKK
Length:184
Mass (Da):21,390
Last modified:November 14, 2006 - v1
Checksum:iEDD2EC0903AA1A8A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei184Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC032633 mRNA. Translation: AAH32633.1.
RefSeqiNP_008958.2. NM_007027.3.
UniGeneiHs.593379.

Genome annotation databases

GeneIDi11073.
KEGGihsa:11073.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ05BV8_HUMAN
AccessioniPrimary (citable) accession number: Q05BV8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: July 5, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.