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Protein
Submitted name:

SMC2 protein

Gene

SMC2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
SMC2 proteinImported
Gene namesi
Name:SMC2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37833.

PTM / Processingi

Proteomic databases

PaxDbiQ05BV1.
PeptideAtlasiQ05BV1.

Expressioni

Gene expression databases

GenevisibleiQ05BV1. HS.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini520 – 640SMC_hingeInterPro annotationAdd BLAST121

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili246 – 294Sequence analysisAdd BLAST49
Coiled coili296 – 365Sequence analysisAdd BLAST70
Coiled coili402 – 502Sequence analysisAdd BLAST101
Coiled coili681 – 725Sequence analysisAdd BLAST45
Coiled coili738 – 781Sequence analysisAdd BLAST44

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0933. Eukaryota.
COG1196. LUCA.
HOGENOMiHOG000163792.
HOVERGENiHBG106605.
KOiK06674.

Family and domain databases

CDDicd03273. ABC_SMC2_euk. 1 hit.
InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
IPR027120. Smc2_ABC.
IPR010935. SMC_hinge.
IPR036277. SMC_hinge_sf.
PfamiView protein in Pfam
PF06470. SMC_hinge. 1 hit.
PF02463. SMC_N. 1 hit.
SMARTiView protein in SMART
SM00968. SMC_hinge. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF75553. SSF75553. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q05BV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHIKSIILEG FKSYAQRTEV NGFDPLFNAI TGLNGSGKSN ILDSICFLLG
60 70 80 90 100
ISNLSQVRAS NLQDLVYKNG QAGITKASVS ITFDNSDKKQ SPLGFEVHDE
110 120 130 140 150
ITVTRQVVIG GRNKYLINGV NANNTRVQDL FCSVGLNVNN PHFLIMQGRI
160 170 180 190 200
TKVLNMKPPE ILSMIEEAAG TRMYEYKKIA AQKTIEKKEA KLKEIKTILE
210 220 230 240 250
EEITPTIQKL KEERSSYLEY QKVMREIEHL SRLYIAYQFL LAEDTKVRSA
260 270 280 290 300
EELKEMQDKV IKLQEELSEN DKKIKALNHE IEELEKRKDK ETGGILRSLE
310 320 330 340 350
DALAEAQRVN TKSQSAFDLK KKNLACEESK RKELEKNMVE DSKTLAAKEK
360 370 380 390 400
EVKKITDGLH ALQEASNKDA EALAAAQQHF NAVSAGLSSN EDGAEATLAG
410 420 430 440 450
QMMACKNDIS KAQTEAKQAQ MKLKHAQQEL KNKQAEVKKM DSGYRKDQEA
460 470 480 490 500
LEAVKRLKEK LEAEMKKLNY EENKEESLLE KRRQLSRDIG RLKETYEALL
510 520 530 540 550
ARFPNLRFAY KDPEKNWNRN CVKGLVASLI SVKDTSATTA LELVAGERLY
560 570 580 590 600
NVVVDTEVTG KKLLERGELK RRYTIIPLNK ISARCIAPET LRVAQNLVGP
610 620 630 640 650
DNVHVALSLV EYKPELQKAM EFVFGTTFVC DNMDNAKKVA FDKRIMTRTV
660 670 680 690 700
TLGGDVFDPH GTLSGGARSQ AASILTKFQE LKDVQDELRI KENELRALEE
710 720 730 740 750
ELAGLKNTAE KYRQLKQQWE MKTEEADLLQ TKLQQSSYHK QQEELDALKK
760 770 780
TIEESEETLK NTKEIQRKAE EKYEVLEKKK K
Length:781
Mass (Da):88,673
Last modified:November 14, 2006 - v1
Checksum:i76C95626487B2ED1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei781Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC032705 mRNA. Translation: AAH32705.1.
RefSeqiNP_001036015.1. NM_001042550.1.
NP_001036016.1. NM_001042551.1.
NP_006435.2. NM_006444.2.
UniGeneiHs.119023.

Genome annotation databases

GeneIDi10592.
KEGGihsa:10592.

Similar proteinsi

Entry informationi

Entry nameiQ05BV1_HUMAN
AccessioniPrimary (citable) accession number: Q05BV1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: October 25, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.