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Q05BR2

- Q05BR2_HUMAN

UniProt

Q05BR2 - Q05BR2_HUMAN

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Protein
Submitted name:

ANXA1 protein

Gene

ANXA1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium-dependent phospholipid binding Source: InterPro
  2. calcium ion binding Source: InterPro
  3. phospholipase A2 inhibitor activity Source: Ensembl

GO - Biological processi

  1. alpha-beta T cell differentiation Source: Ensembl
  2. arachidonic acid secretion Source: Ensembl
  3. cell surface receptor signaling pathway Source: Ensembl
  4. cellular response to glucocorticoid stimulus Source: Ensembl
  5. cellular response to hydrogen peroxide Source: Ensembl
  6. endocrine pancreas development Source: Ensembl
  7. estrous cycle phase Source: Ensembl
  8. gliogenesis Source: Ensembl
  9. hepatocyte differentiation Source: Ensembl
  10. insulin secretion Source: Ensembl
  11. negative regulation of acute inflammatory response Source: Ensembl
  12. negative regulation of apoptotic process Source: Ensembl
  13. negative regulation of protein secretion Source: Ensembl
  14. neutrophil homeostasis Source: Ensembl
  15. positive regulation of G1/S transition of mitotic cell cycle Source: Ensembl
  16. positive regulation of neutrophil apoptotic process Source: Ensembl
  17. positive regulation of prostaglandin biosynthetic process Source: Ensembl
  18. regulation of cell proliferation Source: Ensembl
  19. response to drug Source: Ensembl
  20. response to estradiol Source: Ensembl
  21. response to interleukin-1 Source: Ensembl
  22. response to peptide hormone Source: Ensembl
  23. response to X-ray Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ANXA1 proteinImported
Gene namesi
Name:ANXA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
  2. mitochondrial membrane Source: Ensembl
  3. nucleus Source: Ensembl
  4. protein complex Source: Ensembl
  5. sarcolemma Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ05BR2.

Expressioni

Gene expression databases

BgeeiQ05BR2.
ExpressionAtlasiQ05BR2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ05BR2.
SMRiQ05BR2. Positions 1-45.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

AnnexinSAAS annotation

Family and domain databases

Gene3Di1.10.220.10. 1 hit.
InterProiIPR018502. Annexin_repeat.
[Graphical view]
PfamiPF00191. Annexin. 1 hit.
[Graphical view]
SMARTiSM00335. ANX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q05BR2-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40
MVSRSEIDMN DIKAFYQKMY GISLCQAILD ETKGDYEKIL VALCGGN
Length:47
Mass (Da):5,276
Last modified:November 14, 2006 - v1
Checksum:i669D800C5E9B2355
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC034157 mRNA. Translation: AAH34157.1.
UniGeneiHs.494173.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC034157 mRNA. Translation: AAH34157.1 .
UniGenei Hs.494173.

3D structure databases

ProteinModelPortali Q05BR2.
SMRi Q05BR2. Positions 1-45.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q05BR2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi ANXA1. human.

Gene expression databases

Bgeei Q05BR2.
ExpressionAtlasi Q05BR2. baseline and differential.

Family and domain databases

Gene3Di 1.10.220.10. 1 hit.
InterProi IPR018502. Annexin_repeat.
[Graphical view ]
Pfami PF00191. Annexin. 1 hit.
[Graphical view ]
SMARTi SM00335. ANX. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PlacentaImported.

Entry informationi

Entry nameiQ05BR2_HUMAN
AccessioniPrimary (citable) accession number: Q05BR2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: October 29, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.