Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q05BR2

- Q05BR2_HUMAN

UniProt

Q05BR2 - Q05BR2_HUMAN

Protein
Submitted name:

ANXA1 protein

Gene

ANXA1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. calcium-dependent phospholipid binding Source: InterPro
    2. calcium ion binding Source: InterPro
    3. phospholipase A2 inhibitor activity Source: Ensembl

    GO - Biological processi

    1. alpha-beta T cell differentiation Source: Ensembl
    2. arachidonic acid secretion Source: Ensembl
    3. cell surface receptor signaling pathway Source: Ensembl
    4. cellular response to glucocorticoid stimulus Source: Ensembl
    5. cellular response to hydrogen peroxide Source: Ensembl
    6. endocrine pancreas development Source: Ensembl
    7. estrous cycle phase Source: Ensembl
    8. gliogenesis Source: Ensembl
    9. hepatocyte differentiation Source: Ensembl
    10. insulin secretion Source: Ensembl
    11. negative regulation of acute inflammatory response Source: Ensembl
    12. negative regulation of apoptotic process Source: Ensembl
    13. negative regulation of protein secretion Source: Ensembl
    14. neutrophil homeostasis Source: Ensembl
    15. positive regulation of G1/S transition of mitotic cell cycle Source: Ensembl
    16. positive regulation of neutrophil apoptotic process Source: Ensembl
    17. positive regulation of prostaglandin biosynthetic process Source: Ensembl
    18. regulation of cell proliferation Source: Ensembl
    19. response to drug Source: Ensembl
    20. response to estradiol Source: Ensembl
    21. response to interleukin-1 Source: Ensembl
    22. response to peptide hormone Source: Ensembl
    23. response to X-ray Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    ANXA1 proteinImported
    Gene namesi
    Name:ANXA1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl
    2. mitochondrial membrane Source: Ensembl
    3. nucleus Source: Ensembl
    4. protein complex Source: Ensembl
    5. sarcolemma Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ05BR2.

    Expressioni

    Gene expression databases

    ArrayExpressiQ05BR2.
    BgeeiQ05BR2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ05BR2.
    SMRiQ05BR2. Positions 1-45.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    AnnexinSAAS annotation

    Family and domain databases

    Gene3Di1.10.220.10. 1 hit.
    InterProiIPR018502. Annexin_repeat.
    [Graphical view]
    PfamiPF00191. Annexin. 1 hit.
    [Graphical view]
    SMARTiSM00335. ANX. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q05BR2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVSRSEIDMN DIKAFYQKMY GISLCQAILD ETKGDYEKIL VALCGGN      47
    Length:47
    Mass (Da):5,276
    Last modified:November 14, 2006 - v1
    Checksum:i669D800C5E9B2355
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC034157 mRNA. Translation: AAH34157.1.
    UniGeneiHs.494173.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC034157 mRNA. Translation: AAH34157.1 .
    UniGenei Hs.494173.

    3D structure databases

    ProteinModelPortali Q05BR2.
    SMRi Q05BR2. Positions 1-45.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q05BR2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    ChiTaRSi ANXA1. human.

    Gene expression databases

    ArrayExpressi Q05BR2.
    Bgeei Q05BR2.

    Family and domain databases

    Gene3Di 1.10.220.10. 1 hit.
    InterProi IPR018502. Annexin_repeat.
    [Graphical view ]
    Pfami PF00191. Annexin. 1 hit.
    [Graphical view ]
    SMARTi SM00335. ANX. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: PlacentaImported.

    Entry informationi

    Entry nameiQ05BR2_HUMAN
    AccessioniPrimary (citable) accession number: Q05BR2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 14, 2006
    Last sequence update: November 14, 2006
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.