Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Monocarboxylate transporter 8

Gene

Slc16a2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Monocarboxylate transporter 8Imported
Submitted name:
Slc16a2 proteinImported
Submitted name:
Solute carrier family 16 member 2Imported
Gene namesi
Name:Slc16a2Imported
Synonyms:slc16a2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1203732. Slc16a2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei105 – 12723HelicalSequence analysisAdd
BLAST
Transmembranei147 – 16721HelicalSequence analysisAdd
BLAST
Transmembranei204 – 22724HelicalSequence analysisAdd
BLAST
Transmembranei234 – 25623HelicalSequence analysisAdd
BLAST
Transmembranei268 – 29023HelicalSequence analysisAdd
BLAST
Transmembranei327 – 34317HelicalSequence analysisAdd
BLAST
Transmembranei363 – 38119HelicalSequence analysisAdd
BLAST
Transmembranei393 – 41220HelicalSequence analysisAdd
BLAST
Transmembranei418 – 44225HelicalSequence analysisAdd
BLAST
Transmembranei454 – 47219HelicalSequence analysisAdd
BLAST
Transmembranei484 – 50623HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037629.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini326 – 545220MFSInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IMVZ. Eukaryota.
ENOG410Z4JM. LUCA.
GeneTreeiENSGT00740000115479.
HOVERGENiHBG006387.
KOiK08231.
OMAiIKQTWVL.

Family and domain databases

InterProiIPR030761. MCT8.
IPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PANTHERiPTHR11360:SF123. PTHR11360:SF123. 1 hit.
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q05BA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALPSPASEE AEGPCQEANQ EYQEPVCSPV PEPEPEPEPE PEPDPEPVPV
60 70 80 90 100
PPPEPQPEPE PQPLPDPAPL PELGFEAEPV QEPEPTPTVE TRGTARGFQP
110 120 130 140 150
PEGGFGWIVV FAATWCNGSI FGIHNSVGIL YSMLLEEEKE KNRQVEFQAA
160 170 180 190 200
WVGALAMGMI FFCSPIVSIF TDRLGCRITA TTGAAVAFIG LHTSSFTSSL
210 220 230 240 250
SLRYFTYGIL FGCGCSFAFQ PSLVILGHYF QRRLGLANGV VSAGSSIFSM
260 270 280 290 300
SFPFLIKMLG DKIKLAQTFQ VLSTFMFVLT LLSLTYRPLL PSSQDTPSKR
310 320 330 340 350
GAHTLRQRFL VQFRKYFNMR VFRQRTYRIW AFGIAAAALG YFVPYVHLMK
360 370 380 390 400
YVEDKFKEIK ETWVLLVCIG ATSGLGRLVS GHISDSIPGL KKIYLQVLSF
410 420 430 440 450
LLLGLMSMMI PLCRDFGGLI VVCLFLGLCD GFFITIMAPI AFELVGPMQA
460 470 480 490 500
SQAIGYLLGM MALPMIAGPP IAGLLRNCFG DYHVAFYFAG VPPIIGAVIL
510 520 530 540
FFVPLMHQRM FKKEQRDSSK DKMLSHDPDP NGELLPGSPT PEEPI
Length:545
Mass (Da):60,025
Last modified:November 14, 2006 - v1
Checksum:iACCC7EC6B902A6DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671187 Genomic DNA. No translation available.
BC096587 mRNA. Translation: AAH96587.1.
AB265788 mRNA. Translation: BAF64537.1.
RefSeqiNP_033223.2. NM_009197.2.
UniGeneiMm.388973.

Genome annotation databases

EnsembliENSMUST00000042664; ENSMUSP00000037629; ENSMUSG00000033965.
GeneIDi20502.
KEGGimmu:20502.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671187 Genomic DNA. No translation available.
BC096587 mRNA. Translation: AAH96587.1.
AB265788 mRNA. Translation: BAF64537.1.
RefSeqiNP_033223.2. NM_009197.2.
UniGeneiMm.388973.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037629.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042664; ENSMUSP00000037629; ENSMUSG00000033965.
GeneIDi20502.
KEGGimmu:20502.

Organism-specific databases

CTDi6567.
MGIiMGI:1203732. Slc16a2.

Phylogenomic databases

eggNOGiENOG410IMVZ. Eukaryota.
ENOG410Z4JM. LUCA.
GeneTreeiENSGT00740000115479.
HOVERGENiHBG006387.
KOiK08231.
OMAiIKQTWVL.

Miscellaneous databases

ChiTaRSiSlc16a2. mouse.
SOURCEiSearch...

Family and domain databases

InterProiIPR030761. MCT8.
IPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PANTHERiPTHR11360:SF123. PTHR11360:SF123. 1 hit.
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Mix FVB/NImported.
    Tissue: Mammary tumor. WAP-TGF alpha model. 7 months oldImported.
  2. "Overexpression of MCT8 enhances the differentiation of ES cells into neural progenitors."
    Sugiura M., Nagaoka M., Yabuuchi H., Akaike T.
    Biochem. Biophys. Res. Commun. 360:741-745(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LiverImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (AUG-2015) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ05BA2_MOUSE
AccessioniPrimary (citable) accession number: Q05BA2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: June 8, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.