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Protein
Submitted name:

SARM1 protein

Gene

SARM1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
SARM1 proteinImported
Gene namesi
Name:SARM1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ05B42.
PeptideAtlasiQ05B42.
PRIDEiQ05B42.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000406738.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini305 – 36965SAM (sterile alpha motif)InterPro annotationAdd
BLAST
Domaini379 – 44163SAM (sterile alpha motif)InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG3678. Eukaryota.
ENOG410XQ4A. LUCA.
HOGENOMiHOG000008460.
HOVERGENiHBG079166.

Family and domain databases

Gene3Di1.10.150.50. 2 hits.
1.25.10.10. 1 hit.
3.40.50.10140. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR001660. SAM.
IPR013761. SAM/pointed.
IPR000157. TIR_dom.
[Graphical view]
PfamiPF07647. SAM_2. 2 hits.
PF13676. TIR_2. 1 hit.
[Graphical view]
SMARTiSM00454. SAM. 2 hits.
SM00255. TIR. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 2 hits.
SSF48371. SSF48371. 1 hit.
SSF52200. SSF52200. 1 hit.
PROSITEiPS50105. SAM_DOMAIN. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q05B42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AERLAVPGPD GGGGTGPWWA AGGRGPREVS PGAGTEVQDA LEQILVAENR
60 70 80 90 100
DRVARIGLGV ILNLAKEREP VELARSVAGI LEHMFKHSEE TCQRLVAAGG
110 120 130 140 150
LDAVLYWCRR TDPALLRHCA LALGNCALHG GQAVQRRMVE KRAAEWLFPL
160 170 180 190 200
AFSKEDELLR LHACLAVAVL ATNKEVEREV ERSGTLALVE PLVASLDPGR
210 220 230 240 250
FARCLVDASD TSQGRGPDDL QRLVPLLDSN RLEAQCIGAF YLCAEAAIKS
260 270 280 290 300
LQGKTKVFSD IGAIQSLKRL VSYSTNGTKS ALAKRALRLL GEEVPRPILP
310 320 330 340 350
SVPSWKEAEV QTWLQQIGFS KYCESFREQQ VDGDLLLRLT EEELQTDLGM
360 370 380 390 400
KSGITRKRFF RELTELKTFA NYSTCDRSNL ADWLGSLDPR FRQYTYGLVS
410 420 430 440 450
CGLDRSLLHR VSEQQLLEDC GIHLGVHRAR ILTAAREMLH SPLPCTGGKP
460 470 480 490 500
SGDTPDVFIS YRRNSGSQLA SLLKVHLQLH GFSVFIDVEK LEAGKFEDKL
510 520 530 540 550
IQSVMGARNF VLVLSPGALD KCMQDHDCKD WVHKEIVTAL SCGKNIVPII
560 570 580 590 600
DGFEWPEPQV LPEDMQAVLT FNGIKWSHEY QEATIEKIIR FLQGRSSRDS
610
SAGSDTSLEG AAPMGPT
Length:617
Mass (Da):67,941
Last modified:November 14, 2006 - v1
Checksum:i3BCC5D1E730027FF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC122860 mRNA. Translation: AAI22861.1.
RefSeqiNP_055892.2. NM_015077.3.
UniGeneiHs.743510.

Genome annotation databases

GeneIDi23098.
KEGGihsa:23098.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC122860 mRNA. Translation: AAI22861.1.
RefSeqiNP_055892.2. NM_015077.3.
UniGeneiHs.743510.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000406738.

Proteomic databases

PaxDbiQ05B42.
PeptideAtlasiQ05B42.
PRIDEiQ05B42.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi23098.
KEGGihsa:23098.

Organism-specific databases

CTDi23098.

Phylogenomic databases

eggNOGiKOG3678. Eukaryota.
ENOG410XQ4A. LUCA.
HOGENOMiHOG000008460.
HOVERGENiHBG079166.

Miscellaneous databases

ChiTaRSiSARM1. human.
GenomeRNAii23098.

Family and domain databases

Gene3Di1.10.150.50. 2 hits.
1.25.10.10. 1 hit.
3.40.50.10140. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR001660. SAM.
IPR013761. SAM/pointed.
IPR000157. TIR_dom.
[Graphical view]
PfamiPF07647. SAM_2. 2 hits.
PF13676. TIR_2. 1 hit.
[Graphical view]
SMARTiSM00454. SAM. 2 hits.
SM00255. TIR. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 2 hits.
SSF48371. SSF48371. 1 hit.
SSF52200. SSF52200. 1 hit.
PROSITEiPS50105. SAM_DOMAIN. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiQ05B42_HUMAN
AccessioniPrimary (citable) accession number: Q05B42
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: July 6, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.