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Protein

Mitochondrial coenzyme A transporter SLC25A42

Gene

slc25a42

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial coenzyme A transporter SLC25A42
Alternative name(s):
Solute carrier family 25 member 42
Gene namesi
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-5933592. slc25a42.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei36 – 5621Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei92 – 11221Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei138 – 15821Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei189 – 20921Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei233 – 25321Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei296 – 31621Helical; Name=6Sequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 327327Mitochondrial coenzyme A transporter SLC25A42PRO_0000291822Add
BLAST

Proteomic databases

PaxDbiQ05AQ3.

Expressioni

Gene expression databases

BgeeiENSXETG00000014336.

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000031355.

Structurei

3D structure databases

ProteinModelPortaliQ05AQ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati34 – 12087Solcar 1Add
BLAST
Repeati132 – 21786Solcar 2Add
BLAST
Repeati227 – 31589Solcar 3Add
BLAST

Sequence similaritiesi

Contains 3 Solcar repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0752. Eukaryota.
ENOG410ZRF1. LUCA.
HOGENOMiHOG000165726.
HOVERGENiHBG104402.
InParanoidiQ05AQ3.
KOiK15085.
OrthoDBiEOG091G0C8S.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002167. Graves_DC.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00928. GRAVESDC.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q05AQ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENGIKESQV GLNKNGTHAI LPSPVVSEGH KNHKSILNSL MSGALAGAVA
60 70 80 90 100
KTAVAPLDRT KIIFQVSSNR FSAKEAYRLI YRTYLNEGFL SLWRGNSATM
110 120 130 140 150
VRVIPYAAIQ FCAHEQYKKL LGSYYGFQGS ALTPIPRLLA GALAGTTATI
160 170 180 190 200
ITYPLDLVRA RMAVTPKEMY SNIIHVFMRM SREEGLKSLY RGFTPTVLGV
210 220 230 240 250
IPYAGISFFT YETLKKLHAE HSGRTQPYPF ERLLFGACAG LFGQSASYPL
260 270 280 290 300
DVVRRRMQTA GVTGHAYGSI IGTMQEIVAE EGVIRGLYKG LSMNWVKGPV
310 320
AVGISFTTFD LTQILLKKLQ RLSDIQR
Length:327
Mass (Da):36,036
Last modified:November 14, 2006 - v1
Checksum:i9B7B39C597B9B208
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC124065 mRNA. Translation: AAI24066.1.
RefSeqiNP_001072712.1. NM_001079244.1.
XP_012821282.1. XM_012965828.1.
UniGeneiStr.38611.

Genome annotation databases

GeneIDi780169.
KEGGixtr:780169.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC124065 mRNA. Translation: AAI24066.1.
RefSeqiNP_001072712.1. NM_001079244.1.
XP_012821282.1. XM_012965828.1.
UniGeneiStr.38611.

3D structure databases

ProteinModelPortaliQ05AQ3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000031355.

Proteomic databases

PaxDbiQ05AQ3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi780169.
KEGGixtr:780169.

Organism-specific databases

CTDi284439.
XenbaseiXB-GENE-5933592. slc25a42.

Phylogenomic databases

eggNOGiKOG0752. Eukaryota.
ENOG410ZRF1. LUCA.
HOGENOMiHOG000165726.
HOVERGENiHBG104402.
InParanoidiQ05AQ3.
KOiK15085.
OrthoDBiEOG091G0C8S.

Gene expression databases

BgeeiENSXETG00000014336.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002167. Graves_DC.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00928. GRAVESDC.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiS2542_XENTR
AccessioniPrimary (citable) accession number: Q05AQ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: November 14, 2006
Last modified: September 7, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.