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Protein

Mitochondrial coenzyme A transporter SLC25A42

Gene

slc25a42

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial coenzyme A transporter SLC25A42
Alternative name(s):
Solute carrier family 25 member 42
Gene namesi
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-5933592 slc25a42

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 56Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei92 – 112Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei138 – 158Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei189 – 209Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei233 – 253Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei296 – 316Helical; Name=6Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002918221 – 327Mitochondrial coenzyme A transporter SLC25A42Add BLAST327

Proteomic databases

PaxDbiQ05AQ3

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000031355

Structurei

3D structure databases

ProteinModelPortaliQ05AQ3
SMRiQ05AQ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati34 – 120Solcar 1Add BLAST87
Repeati132 – 217Solcar 2Add BLAST86
Repeati227 – 315Solcar 3Add BLAST89

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0752 Eukaryota
ENOG410ZRF1 LUCA
HOGENOMiHOG000165726
HOVERGENiHBG104402
InParanoidiQ05AQ3
KOiK15085
OrthoDBiEOG091G0C8S

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002167 Graves_DC
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00928 GRAVESDC
PR00926 MITOCARRIER
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

Q05AQ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENGIKESQV GLNKNGTHAI LPSPVVSEGH KNHKSILNSL MSGALAGAVA
60 70 80 90 100
KTAVAPLDRT KIIFQVSSNR FSAKEAYRLI YRTYLNEGFL SLWRGNSATM
110 120 130 140 150
VRVIPYAAIQ FCAHEQYKKL LGSYYGFQGS ALTPIPRLLA GALAGTTATI
160 170 180 190 200
ITYPLDLVRA RMAVTPKEMY SNIIHVFMRM SREEGLKSLY RGFTPTVLGV
210 220 230 240 250
IPYAGISFFT YETLKKLHAE HSGRTQPYPF ERLLFGACAG LFGQSASYPL
260 270 280 290 300
DVVRRRMQTA GVTGHAYGSI IGTMQEIVAE EGVIRGLYKG LSMNWVKGPV
310 320
AVGISFTTFD LTQILLKKLQ RLSDIQR
Length:327
Mass (Da):36,036
Last modified:November 14, 2006 - v1
Checksum:i9B7B39C597B9B208
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC124065 mRNA Translation: AAI24066.1
RefSeqiNP_001072712.1, NM_001079244.1
XP_012821282.1, XM_012965828.2
UniGeneiStr.38611

Genome annotation databases

GeneIDi780169
KEGGixtr:780169

Similar proteinsi

Entry informationi

Entry nameiS2542_XENTR
AccessioniPrimary (citable) accession number: Q05AQ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: November 14, 2006
Last modified: April 25, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health