Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q05AL2 (PPM1H_DANRE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein phosphatase 1H
EC=3.1.3.16
Gene names
Name:ppm1h
ORF Names:zgc:153678
OrganismDanio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]
Taxonomic identifier7955 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length516 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

A phosphoprotein + H2O = a protein + phosphate.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Ontologies

Keywords
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmetabolic process

Inferred from electronic annotation. Source: GOC

   Molecular_functionphosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 516516Protein phosphatase 1H
PRO_0000286606

Regions

Domain92 – 506415PP2C-like

Sequences

Sequence LengthMass (Da)Tools
Q05AL2 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: E13BF19741EFA0BD

FASTA51656,561
        10         20         30         40         50         60 
MMTRVRSAVS SIIGGIMASG TGAHDSHPDL PLRFPYSRPD FLALSPDEVE CSADHISRPI 

        70         80         90        100        110        120 
LILKEMKLPW ATGYAEVINA GKSALNEDQA CCEVVELRKR PADPSSVSYT PSRRRSSLPS 

       130        140        150        160        170        180 
GDVLDTIHNP EVKELDFHYW ALFDGHGGSG AAVFAAKFLH LHIEEQLQEV LEILQDPGLQ 

       190        200        210        220        230        240 
PPTCLGEESP NPQLHASASG SQRGLSRAAS LRGAAGAPGS PNTMAPRFFM EKKIKQESLV 

       250        260        270        280        290        300 
VGAIENAFKE MDAHIARERC AYSISGGCTA LAVMFLLGKL YVANAGDSRA LIVRAGELIT 

       310        320        330        340        350        360 
MSSSFTPESE RQRLQFLAHL QPSLLGSDFT HLEFPRRVTK REIGKRMLYR DFTMNGWAYK 

       370        380        390        400        410        420 
TVQEEDLKFP LIYGEGKKAR VLATIGITRG LGDHDLKVHD SDIAIKPFLS CSPEVQVYNL 

       430        440        450        460        470        480 
CQFEHGADDV LILATDGLWD VLSNQEVADA VSGFLGNCDP DDQHRYTMAA QDLVMKARGI 

       490        500        510 
LKDRGWRIAG DRLGSGDDIS VFIIPLMYGT QQPQPS

« Hide

References

[1]NIH - Zebrafish Gene Collection (ZGC) project
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Ovary.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC124421 mRNA. Translation: AAI24422.1.
IPIIPI00810538.
RefSeqNP_001070923.1. NM_001077455.1.
UniGeneDr.79638.

3D structure databases

ProteinModelPortalQ05AL2.
ModBaseSearch...

Protein-protein interaction databases

STRING7955.ENSDARP00000087709.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID768291.
KEGGdre:768291.

Organism-specific databases

CTD57460.
ZFINZDB-GENE-061027-190. ppm1h.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000251606.
HOVERGENHBG105802.
InParanoidQ05AL2.
KOK01090.
OrthoDBEOG4PG60S.

Family and domain databases

Gene3D3.60.40.10. 3 hits.
InterProIPR001932. PP2C-like.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 2 hits.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. PP2C-related. 1 hit.
PROSITEPS01032. PP2C. False negative.
[Graphical view]
ProtoNetSearch...

Other

NextBio20918555.

Entry information

Entry namePPM1H_DANRE
AccessionPrimary (citable) accession number: Q05AL2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: November 14, 2006
Last modified: April 3, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents