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Protein

Protein phosphatase 1H

Gene

ppm1h

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

  1. phosphoprotein phosphatase activity Source: UniProtKB

GO - Biological processi

  1. dephosphorylation Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase 1H (EC:3.1.3.16)
Gene namesi
Name:ppm1h
ORF Names:zgc:153678
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437 Componenti: Unplaced

Organism-specific databases

ZFINiZDB-GENE-061027-190. ppm1h.

Subcellular locationi

  1. Nucleus By similarity
  2. Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
  2. nucleus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 516516Protein phosphatase 1HPRO_0000286606Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000087709.

Structurei

3D structure databases

ProteinModelPortaliQ05AL2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini106 – 506401PPM-type phosphatasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000251606.
HOVERGENiHBG105802.
InParanoidiQ05AL2.
KOiK17503.
PhylomeDBiQ05AL2.

Family and domain databases

Gene3Di3.60.40.10. 3 hits.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 2 hits.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 4 hits.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q05AL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMTRVRSAVS SIIGGIMASG TGAHDSHPDL PLRFPYSRPD FLALSPDEVE
60 70 80 90 100
CSADHISRPI LILKEMKLPW ATGYAEVINA GKSALNEDQA CCEVVELRKR
110 120 130 140 150
PADPSSVSYT PSRRRSSLPS GDVLDTIHNP EVKELDFHYW ALFDGHGGSG
160 170 180 190 200
AAVFAAKFLH LHIEEQLQEV LEILQDPGLQ PPTCLGEESP NPQLHASASG
210 220 230 240 250
SQRGLSRAAS LRGAAGAPGS PNTMAPRFFM EKKIKQESLV VGAIENAFKE
260 270 280 290 300
MDAHIARERC AYSISGGCTA LAVMFLLGKL YVANAGDSRA LIVRAGELIT
310 320 330 340 350
MSSSFTPESE RQRLQFLAHL QPSLLGSDFT HLEFPRRVTK REIGKRMLYR
360 370 380 390 400
DFTMNGWAYK TVQEEDLKFP LIYGEGKKAR VLATIGITRG LGDHDLKVHD
410 420 430 440 450
SDIAIKPFLS CSPEVQVYNL CQFEHGADDV LILATDGLWD VLSNQEVADA
460 470 480 490 500
VSGFLGNCDP DDQHRYTMAA QDLVMKARGI LKDRGWRIAG DRLGSGDDIS
510
VFIIPLMYGT QQPQPS
Length:516
Mass (Da):56,561
Last modified:November 14, 2006 - v1
Checksum:iE13BF19741EFA0BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC124421 mRNA. Translation: AAI24422.1.
RefSeqiNP_001070923.1. NM_001077455.1.
UniGeneiDr.79638.

Genome annotation databases

GeneIDi768291.
KEGGidre:768291.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC124421 mRNA. Translation: AAI24422.1.
RefSeqiNP_001070923.1. NM_001077455.1.
UniGeneiDr.79638.

3D structure databases

ProteinModelPortaliQ05AL2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000087709.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi768291.
KEGGidre:768291.

Organism-specific databases

CTDi57460.
ZFINiZDB-GENE-061027-190. ppm1h.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000251606.
HOVERGENiHBG105802.
InParanoidiQ05AL2.
KOiK17503.
PhylomeDBiQ05AL2.

Miscellaneous databases

NextBioi20918555.
PROiQ05AL2.

Family and domain databases

Gene3Di3.60.40.10. 3 hits.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 2 hits.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 4 hits.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Ovary.

Entry informationi

Entry nameiPPM1H_DANRE
AccessioniPrimary (citable) accession number: Q05AL2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: November 14, 2006
Last modified: April 1, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.