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Protein
Submitted name:

GATA-binding protein 1

Gene

gata1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • chordate embryonic development Source: ZFIN
  • embryonic hemopoiesis Source: ZFIN
  • erythrocyte development Source: ZFIN
  • erythrocyte differentiation Source: ZFIN
  • macrophage differentiation Source: ZFIN
  • monocyte differentiation Source: ZFIN
  • myeloid cell differentiation Source: ZFIN
  • negative regulation of apoptotic process Source: ZFIN
  • negative regulation of gene expression Source: ZFIN
  • neutrophil differentiation Source: ZFIN
  • positive regulation of transcription from RNA polymerase II promoter Source: ZFIN
  • primitive hemopoiesis Source: ZFIN
  • regulation of myeloid cell differentiation Source: ZFIN

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-DRE-983231. Factors involved in megakaryocyte development and platelet production.

Names & Taxonomyi

Protein namesi
Submitted name:
GATA-binding protein 1Imported
Submitted name:
GATA-binding protein 1aImported
Submitted name:
Gata1 proteinImported
Gene namesi
Name:gata1aImported
Synonyms:gata1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 11

Organism-specific databases

ZFINiZDB-GENE-980526-268. gata1a.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSDARG00000013477.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000002330.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini232 – 287GATA-typeInterPro annotationAdd BLAST56
Domaini286 – 339GATA-typeInterPro annotationAdd BLAST54

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1601. Eukaryota.
COG5641. LUCA.
GeneTreeiENSGT00760000119221.
HOGENOMiHOG000047701.
HOVERGENiHBG051705.
OMAiQSHWASP.
OrthoDBiEOG091G0AUR.
TreeFamiTF315391.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR016374. TF_GATA-2/3.
IPR000679. Znf_GATA.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00320. GATA. 2 hits.
PIRSFiPIRSF003027. TF_GATA-1/2/3. 2 hits.
PRINTSiPR00619. GATAZNFINGER.
SMARTiView protein in SMART
SM00401. ZnF_GATA. 2 hits.
PROSITEiView protein in PROSITE
PS00344. GATA_ZN_FINGER_1. 2 hits.
PS50114. GATA_ZN_FINGER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q05AJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENSSEPSRW VSPGLLSPDP LVNYTTDSGL LPPVDVDEPF YSSSETDLLP
60 70 80 90 100
SYYSTSVQSR ASSSYRHSPV RQVYSSQSIL GNIQWLDNSA GHSLNSPYNP
110 120 130 140 150
TSTVWSSSPF AKTPLHSHTS TSIYQNTATP SFTSPKEGFP SPSRDGKDSP
160 170 180 190 200
RLQEVLKAER LSPMSGSGSS FLNLSSATGG VYGPSPHMLS PYGSYMSTSQ
210 220 230 240 250
DYSSAALYST GGPWMSPSSY SPKLRNKMRL SPPEARECVN CGATATPLWR
260 270 280 290 300
RDGTGHYLCN ACGLYHKMNG QNRPLIRPKK RLIVSKRAGT QCANCHTSTT
310 320 330 340 350
TLWRRNASGE PVCNACGLYF KLHNVNRPLT MKKDGIQTRN RKVSNRNKKG
360 370 380 390 400
KKNAASEVYP DMSHMAPPDE HVGAYSLNPG PLLSYSHPAH LLPTSTLHSS
410
TTLPYTHHPN SGMMPTLV
Length:418
Mass (Da):45,665
Last modified:November 14, 2006 - v1
Checksum:iEF3004D9010BC203
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR932000 Genomic DNA. No translation available.
BC124483 mRNA. Translation: AAI24484.1.
BC164788 mRNA. Translation: AAI64788.1.
UniGeneiDr.355.

Genome annotation databases

EnsembliENSDART00000013714; ENSDARP00000002330; ENSDARG00000013477.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ05AJ3_DANRE
AccessioniPrimary (citable) accession number: Q05AJ3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: June 7, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported