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Protein
Submitted name:

GATA-binding protein 1a

Gene

gata1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • chordate embryonic development Source: ZFIN
  • embryonic hemopoiesis Source: ZFIN
  • erythrocyte development Source: ZFIN
  • erythrocyte differentiation Source: ZFIN
  • macrophage differentiation Source: ZFIN
  • monocyte differentiation Source: ZFIN
  • myeloid cell differentiation Source: ZFIN
  • negative regulation of apoptotic process Source: ZFIN
  • negative regulation of gene expression Source: ZFIN
  • neutrophil differentiation Source: ZFIN
  • positive regulation of transcription by RNA polymerase II Source: ZFIN
  • primitive hemopoiesis Source: ZFIN
  • regulation of myeloid cell differentiation Source: ZFIN

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-DRE-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
R-DRE-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs
R-DRE-983231 Factors involved in megakaryocyte development and platelet production

Names & Taxonomyi

Protein namesi
Submitted name:
GATA-binding protein 1aImported
Submitted name:
Gata1 proteinImported
Gene namesi
Name:gata1aImported
Synonyms:gata1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 11

Organism-specific databases

ZFINiZDB-GENE-980526-268 gata1a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000013477

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000002330

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini232 – 287GATA-typeInterPro annotationAdd BLAST56
Domaini286 – 339GATA-typeInterPro annotationAdd BLAST54

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1601 Eukaryota
COG5641 LUCA
GeneTreeiENSGT00760000119221
HOGENOMiHOG000047701
HOVERGENiHBG051705
OMAiQSHWASP
OrthoDBiEOG091G0AUR
TreeFamiTF315391

Family and domain databases

Gene3Di3.30.50.10, 2 hits
InterProiView protein in InterPro
IPR016374 TF_GATA-2/3
IPR000679 Znf_GATA
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00320 GATA, 2 hits
PIRSFiPIRSF003027 TF_GATA-1/2/3, 2 hits
PRINTSiPR00619 GATAZNFINGER
SMARTiView protein in SMART
SM00401 ZnF_GATA, 2 hits
PROSITEiView protein in PROSITE
PS00344 GATA_ZN_FINGER_1, 2 hits
PS50114 GATA_ZN_FINGER_2, 2 hits

Sequencei

Sequence statusi: Complete.

Q05AJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENSSEPSRW VSPGLLSPDP LVNYTTDSGL LPPVDVDEPF YSSSETDLLP
60 70 80 90 100
SYYSTSVQSR ASSSYRHSPV RQVYSSQSIL GNIQWLDNSA GHSLNSPYNP
110 120 130 140 150
TSTVWSSSPF AKTPLHSHTS TSIYQNTATP SFTSPKEGFP SPSRDGKDSP
160 170 180 190 200
RLQEVLKAER LSPMSGSGSS FLNLSSATGG VYGPSPHMLS PYGSYMSTSQ
210 220 230 240 250
DYSSAALYST GGPWMSPSSY SPKLRNKMRL SPPEARECVN CGATATPLWR
260 270 280 290 300
RDGTGHYLCN ACGLYHKMNG QNRPLIRPKK RLIVSKRAGT QCANCHTSTT
310 320 330 340 350
TLWRRNASGE PVCNACGLYF KLHNVNRPLT MKKDGIQTRN RKVSNRNKKG
360 370 380 390 400
KKNAASEVYP DMSHMAPPDE HVGAYSLNPG PLLSYSHPAH LLPTSTLHSS
410
TTLPYTHHPN SGMMPTLV
Length:418
Mass (Da):45,665
Last modified:November 14, 2006 - v1
Checksum:iEF3004D9010BC203
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR932000 Genomic DNA No translation available.
BC124483 mRNA Translation: AAI24484.1
BC164788 mRNA Translation: AAI64788.1
UniGeneiDr.355

Genome annotation databases

EnsembliENSDART00000013714; ENSDARP00000002330; ENSDARG00000013477
ENSDART00000190542; ENSDARP00000156542; ENSDARG00000117116

Similar proteinsi

Entry informationi

Entry nameiQ05AJ3_DANRE
AccessioniPrimary (citable) accession number: Q05AJ3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: June 20, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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