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Protein
Submitted name:

CD70 antigen

Gene

Cd70

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CD70 antigenImported
Submitted name:
Tumor necrosis factor (Ligand) superfamily, member 7Imported
Submitted name:
Tumor necrosis factor ligand 8aImported
Gene namesi
Name:Cd70Imported
Synonyms:Tnfsf7Imported, Tnlg8aImported
ORF Names:mCG_5599Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1195273. Cd70.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 44HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000019489.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000019633.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 190TNF_2InterPro annotationAdd BLAST131

Sequence similaritiesi

Belongs to the tumor necrosis factor family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IY7F. Eukaryota.
ENOG41119T2. LUCA.
HOVERGENiHBG054184.
KOiK05470.
OMAiQVTLANC.
OrthoDBiEOG091G0QAO.

Family and domain databases

Gene3Di2.60.120.40. 1 hit.
InterProiIPR006052. TNF_dom.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view]
PfamiPF00229. TNF. 1 hit.
[Graphical view]
SMARTiSM00207. TNF. 1 hit.
[Graphical view]
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiPS50049. TNF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q05A52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEEGRPCPW VRWSGTAFQR QWPWLLLVVF ITVFCCWFHC SGLLSKQQQR
60 70 80 90 100
LLEHPEPHTA ELQLNLTVPR KDPTLRWGAG PALGRSFTHG PELEEGHLRI
110 120 130 140 150
HQDGLYRLHI QVTLANCSSP GSTLQHRATL AVGICSPAAH GISLLRGRFG
160 170 180 190
QDCTVALQRL TYLVHGDVLC TNLTLPLLPS RNADETFFGV QWICP
Length:195
Mass (Da):21,919
Last modified:November 14, 2006 - v1
Checksum:iBD14671A2C8E26C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC125407 mRNA. Translation: AAI25408.1.
BC125409 mRNA. Translation: AAI25410.1.
LN874403 mRNA. Translation: CTQ86168.1.
CH466537 Genomic DNA. Translation: EDL38239.1.
RefSeqiNP_035747.1. NM_011617.2.
UniGeneiMm.42228.

Genome annotation databases

GeneIDi21948.
KEGGimmu:21948.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC125407 mRNA. Translation: AAI25408.1.
BC125409 mRNA. Translation: AAI25410.1.
LN874403 mRNA. Translation: CTQ86168.1.
CH466537 Genomic DNA. Translation: EDL38239.1.
RefSeqiNP_035747.1. NM_011617.2.
UniGeneiMm.42228.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000019633.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi21948.
KEGGimmu:21948.

Organism-specific databases

CTDi970.
MGIiMGI:1195273. Cd70.

Phylogenomic databases

eggNOGiENOG410IY7F. Eukaryota.
ENOG41119T2. LUCA.
HOVERGENiHBG054184.
KOiK05470.
OMAiQVTLANC.
OrthoDBiEOG091G0QAO.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000019489.

Family and domain databases

Gene3Di2.60.120.40. 1 hit.
InterProiIPR006052. TNF_dom.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view]
PfamiPF00229. TNF. 1 hit.
[Graphical view]
SMARTiSM00207. TNF. 1 hit.
[Graphical view]
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiPS50049. TNF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ05A52_MOUSE
AccessioniPrimary (citable) accession number: Q05A52
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: November 2, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.