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Protein

DC-STAMP domain-containing protein 1

Gene

Dcst1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri672 – 71140RING-type; degenerateAdd
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
DC-STAMP domain-containing protein 1
Gene namesi
Name:Dcst1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1925022. Dcst1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 4646CytoplasmicSequence analysisAdd
BLAST
Transmembranei47 – 6721HelicalSequence analysisAdd
BLAST
Topological domaini68 – 769ExtracellularSequence analysis
Transmembranei77 – 9721HelicalSequence analysisAdd
BLAST
Topological domaini98 – 10710CytoplasmicSequence analysis
Transmembranei108 – 12821HelicalSequence analysisAdd
BLAST
Topological domaini129 – 394266ExtracellularSequence analysisAdd
BLAST
Transmembranei395 – 41521HelicalSequence analysisAdd
BLAST
Topological domaini416 – 48974CytoplasmicSequence analysisAdd
BLAST
Transmembranei490 – 51021HelicalSequence analysisAdd
BLAST
Topological domaini511 – 57666ExtracellularSequence analysisAdd
BLAST
Transmembranei577 – 59721HelicalSequence analysisAdd
BLAST
Topological domaini598 – 732135CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 732732DC-STAMP domain-containing protein 1PRO_0000278825Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi184 – 1841N-linked (GlcNAc...)Sequence analysis
Glycosylationi217 – 2171N-linked (GlcNAc...)Sequence analysis
Glycosylationi346 – 3461N-linked (GlcNAc...)Sequence analysis
Glycosylationi374 – 3741N-linked (GlcNAc...)Sequence analysis
Glycosylationi551 – 5511N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ059Y8.
PRIDEiQ059Y8.

PTM databases

PhosphoSiteiQ059Y8.

Expressioni

Gene expression databases

BgeeiQ059Y8.
CleanExiMM_DCST1.
GenevisibleiQ059Y8. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000065502.

Family & Domainsi

Sequence similaritiesi

Contains 1 RING-type zinc finger.Curated

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri672 – 71140RING-type; degenerateAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helix, Zinc-finger

Phylogenomic databases

eggNOGiKOG3726. Eukaryota.
ENOG410ZWQR. LUCA.
GeneTreeiENSGT00730000110972.
HOGENOMiHOG000112180.
HOVERGENiHBG081422.
InParanoidiQ059Y8.
OMAiLMAKPFT.
OrthoDBiEOG79GT5Q.
TreeFamiTF318254.

Family and domain databases

InterProiIPR012858. DC_STAMP-like.
[Graphical view]
PfamiPF07782. DC_STAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q059Y8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFLSSTLHS LGIFEKISRI KEVLKNRLLD LTKRRDQARE QQRKRPHTII
60 70 80 90 100
QGLLLWSLPV SWIRFLWRQP GEFPVTAFLL GAGTGGLLAI GLFQLLVNPM
110 120 130 140 150
NIYEEQKVVA LYCLASLGAI GWGTSPHIRC ASLLLVPKML GKEGRLFVMG
160 170 180 190 200
YALAAIYSGP AANLRSNINE VIASLGCTVE LQINNTRSAW RVSTAPLRAV
210 220 230 240 250
FKGMVGSKDS LNKEIQNVST SFEEMDEQVK SDAGYSSEDW DKNRESTEMF
260 270 280 290 300
GTSRVRPYLS TQMVYELRTR LRCIHVVNKA ILSCYRWFDK KHKNCMRRIH
310 320 330 340 350
LPLFNNMICV PMKFKFLCNI AKVIEIWCYK RIPVEGNFGQ TYDSVNQSIH
360 370 380 390 400
GLSGEFSANI NLKEEKQSSM VGLNTTNWEH MGTEVRDYVR QQETYLQWAM
410 420 430 440 450
GLLHVLLSCT FLLVFHSAFS YMDHYNWDIR FDNIYISTYF CQIDARRKKL
460 470 480 490 500
GKQSLLPLRK AERKTVIFPF KATIQAWEMR YVIRELLETL PIVLLLLVLC
510 520 530 540 550
AIDWALYSVF DTIRQHSFVQ YSFRSSHKLE IKVEGDSILA KLLRKTIGAL
560 570 580 590 600
NTSSSTDVET NNMPCLPQPI SLNARDYFKA SLPTLLLVCL CLAQAFGYRL
610 620 630 640 650
RRVIAAFYFP KREKKRALFF YNEFLKKRSA FTKLRRAAIV RRANQQKAPP
660 670 680 690 700
HYLVEALYRR CPLLHRFMRQ RCVVCQAMET PDSYVCPTPD CKALYCRSCW
710 720 730
DDMQRLCPVC TPREELSSSA HSDSNDDAVY GD
Length:732
Mass (Da):84,332
Last modified:November 14, 2006 - v1
Checksum:i22AB2CD98AC17CD9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC125478 mRNA. Translation: AAI25479.1.
BC125480 mRNA. Translation: AAI25481.1.
CCDSiCCDS38490.1.
RefSeqiNP_084250.1. NM_029974.2.
UniGeneiMm.164013.

Genome annotation databases

EnsembliENSMUST00000070820; ENSMUSP00000065502; ENSMUSG00000042672.
GeneIDi77772.
KEGGimmu:77772.
UCSCiuc008pyy.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC125478 mRNA. Translation: AAI25479.1.
BC125480 mRNA. Translation: AAI25481.1.
CCDSiCCDS38490.1.
RefSeqiNP_084250.1. NM_029974.2.
UniGeneiMm.164013.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000065502.

PTM databases

PhosphoSiteiQ059Y8.

Proteomic databases

PaxDbiQ059Y8.
PRIDEiQ059Y8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000070820; ENSMUSP00000065502; ENSMUSG00000042672.
GeneIDi77772.
KEGGimmu:77772.
UCSCiuc008pyy.1. mouse.

Organism-specific databases

CTDi149095.
MGIiMGI:1925022. Dcst1.

Phylogenomic databases

eggNOGiKOG3726. Eukaryota.
ENOG410ZWQR. LUCA.
GeneTreeiENSGT00730000110972.
HOGENOMiHOG000112180.
HOVERGENiHBG081422.
InParanoidiQ059Y8.
OMAiLMAKPFT.
OrthoDBiEOG79GT5Q.
TreeFamiTF318254.

Miscellaneous databases

PROiQ059Y8.
SOURCEiSearch...

Gene expression databases

BgeeiQ059Y8.
CleanExiMM_DCST1.
GenevisibleiQ059Y8. MM.

Family and domain databases

InterProiIPR012858. DC_STAMP-like.
[Graphical view]
PfamiPF07782. DC_STAMP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiDCST1_MOUSE
AccessioniPrimary (citable) accession number: Q059Y8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: November 14, 2006
Last modified: June 8, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.