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Protein
Submitted name:

A kinase (PRKA) anchor protein 8

Gene

Akap8

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
A kinase (PRKA) anchor protein 8Imported
Submitted name:
A kinase (PRKA) anchor protein 8, isoform CRA_cImported
Gene namesi
Name:Akap8Imported
ORF Names:mCG_14243Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1928488. Akap8.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PeptideAtlasiQ059U9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000024045.
ExpressionAtlasiQ059U9. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ059U9. 1 interactor.
STRINGi10090.ENSMUSP00000002699.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini389 – 411C2H2 AKAP95-typeInterPro annotationAdd BLAST23
Domaini478 – 501C2H2 AKAP95-typeInterPro annotationAdd BLAST24

Sequence similaritiesi

Belongs to the AKAP95 family.PROSITE-ProRule annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IFNG. Eukaryota.
ENOG410YE5A. LUCA.
HOVERGENiHBG053198.
KOiK16525.
OMAiGCGRSQT.
OrthoDBiEOG091G0836.

Family and domain databases

InterProiView protein in InterPro
IPR007071. AKAP95.
IPR034736. ZF_C2H2_AKAP95.
PANTHERiPTHR12190. PTHR12190. 1 hit.
PfamiView protein in Pfam
PF04988. AKAP95. 1 hit.
PROSITEiView protein in PROSITE
PS51799. ZF_C2H2_AKAP95. 2 hits.

Sequencei

Sequence statusi: Complete.

Q059U9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQGYGGYGA WSAGPANTQG TYGSGMTSWQ GYENYNYYNA QNTSVPAGTP
60 70 80 90 100
YSYGPASWEA TKTNDGGLAA GSPAMHVASF APEPCTDNSD SLIAKINQRL
110 120 130 140 150
DMLSKEGGRG GISSGGEGVQ DRDSSFRFQP YESYDARPCI PEHNPYRPGY
160 170 180 190 200
GYDYDFDLGT DRNGSFGGTF NDCRDPAPER GSLDGFLRGR GQGRFQDRSN
210 220 230 240 250
SSTFIRSDPF MPPSASEPLS TTWNELNYMG GRGLGGPSTS RPPPSLFSQS
260 270 280 290 300
MAPDYSMMGM QGVGGFGGTM PYGCGRSQTR IRDWPRRRGF ERFGPDNMGR
310 320 330 340 350
KRKQFPLYEE PDAKLARADS DGDLSENDDG AGDLRSGDEE FRGEDDLCDS
360 370 380 390 400
RKQRGEKEDE DEDVKKRREK QRRRDRMRDR AADRIQFACS VCKFRSFEDE
410 420 430 440 450
EIQKHLQSKF HKETLRFIST KLPDKTVEFL QEYIINRNKK IEKRRQELLE
460 470 480 490 500
KESPKPKPDP FKGIGQEHFF KKIEAAHCLA CDMLIPAQHQ LLQRHLHSVD
510 520 530 540 550
HNHNRRLAAE QFKKTSLHVA KSVLNNKHIV KMLEKYLKGE DPFVNETADL
560 570 580 590 600
ETEGDENVGE EKEETPEEVA AEVLAEVITA AVKAVEGEGE PAAAHSDVLT
610 620 630 640 650
EVEGPVDTAE ASSDPHTEKL LEEQTCEAAS ETRSIEDKTR GEAAEARNEA
660 670 680
AMPTADAGST LPVIAIPGIM EDELEQTGAE AKDIPTE
Length:687
Mass (Da):76,294
Last modified:November 14, 2006 - v1
Checksum:iBC1E320216A47E10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC125521 mRNA. Translation: AAI25522.1.
BC137746 mRNA. Translation: AAI37747.1.
CH466640 Genomic DNA. Translation: EDL40325.1.
RefSeqiNP_062748.2. NM_019774.5.
UniGeneiMm.328945.

Genome annotation databases

GeneIDi56399.
KEGGimmu:56399.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC125521 mRNA. Translation: AAI25522.1.
BC137746 mRNA. Translation: AAI37747.1.
CH466640 Genomic DNA. Translation: EDL40325.1.
RefSeqiNP_062748.2. NM_019774.5.
UniGeneiMm.328945.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ059U9. 1 interactor.
STRINGi10090.ENSMUSP00000002699.

Proteomic databases

PeptideAtlasiQ059U9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi56399.
KEGGimmu:56399.

Organism-specific databases

CTDi10270.
MGIiMGI:1928488. Akap8.

Phylogenomic databases

eggNOGiENOG410IFNG. Eukaryota.
ENOG410YE5A. LUCA.
HOVERGENiHBG053198.
KOiK16525.
OMAiGCGRSQT.
OrthoDBiEOG091G0836.

Miscellaneous databases

ChiTaRSiAkap8. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000024045.
ExpressionAtlasiQ059U9. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR007071. AKAP95.
IPR034736. ZF_C2H2_AKAP95.
PANTHERiPTHR12190. PTHR12190. 1 hit.
PfamiView protein in Pfam
PF04988. AKAP95. 1 hit.
PROSITEiView protein in PROSITE
PS51799. ZF_C2H2_AKAP95. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ059U9_MOUSE
AccessioniPrimary (citable) accession number: Q059U9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: April 12, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.