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Protein

60 kDa chaperonin 1

Gene

groL1

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 1UniRule annotation
Alternative name(s):
GroEL protein 1UniRule annotation
Protein Cpn60 1UniRule annotation
Gene namesi
Name:groL1UniRule annotation
Synonyms:cpn60-1, groEL-1UniRule annotation, groEL1UniRule annotation
Ordered Locus Names:slr2076
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved3 Publications
ChainiPRO_00000635752 – 54160 kDa chaperonin 1Add BLAST540

Proteomic databases

PaxDbiQ05972
PRIDEiQ05972

Expressioni

Inductioni

By stress conditions e.g. heat shock.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Binary interactionsi

WithEntry#Exp.IntActNotes
trxAP522314EBI-862119,EBI-862916

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ05972, 2 interactors
STRINGi1148.SYNGTS_0837

Structurei

3D structure databases

ProteinModelPortaliQ05972
SMRiQ05972
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290
InParanoidiQ05972
KOiK04077
OMAiTDTDKME
PhylomeDBiQ05972

Family and domain databases

CDDicd03344 GroEL, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
HAMAPiMF_00600 CH60, 1 hit
InterProiView protein in InterPro
IPR018370 Chaperonin_Cpn60_CS
IPR001844 Chaprnin_Cpn60
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00298 CHAPERONIN60
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 1 hit
TIGRFAMsiTIGR02348 GroEL, 1 hit
PROSITEiView protein in PROSITE
PS00296 CHAPERONINS_CPN60, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q05972-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKSIIYNDE ARRALERGMD ILAEAVAVTL GPKGRNVVLE KKFGSPQIIN
60 70 80 90 100
DGITIAKEIE LEDHVENTGV SLIRQAASKT NDVAGDGTTT ATVLAHAIVK
110 120 130 140 150
EGLRNVAAGA NPISLKRGID KATDFLVARI KEHAQPVGDS KAIAQVGAIS
160 170 180 190 200
AGNDEEVGQM IANAMDKVGQ EGVISLEEGK SMTTELEITE GMRFDKGYIS
210 220 230 240 250
PYFVTDAERM EAVLEDPRIL ITDKKINLVQ DLVPILEQVA RQGKPLLIIA
260 270 280 290 300
EDIEKEALAT LVVNRLRGVL NVAAVKAPGF GDRRKQMLED IATLTGGQVI
310 320 330 340 350
SEDAGLKLES ATVDSLGSAR RINITKDNTT IVAEGNEAAV KSRCEQIRRQ
360 370 380 390 400
IEETDSSYDK EKLQERLAKL AGGVAVIKVG AATETEMKDR KLRLEDAINA
410 420 430 440 450
TKAAVEEGIV PGGGTTLAHL APQLEDWATG NLKDEELTGA LIVARALPAP
460 470 480 490 500
LKRIAENAGQ NGAVISERVK EKEFNVGYNA ASLEYVDMLA AGIVDPAKVT
510 520 530 540
RSALQNAASI AGMVLTTECI VVDKPEKEKA PAGAPGGDFD Y
Length:541
Mass (Da):57,653
Last modified:January 23, 2007 - v4
Checksum:i37E158A939CBFCB8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti12R → T AA sequence (PubMed:1346251).Curated1
Sequence conflicti91A → D in BAA02180 (PubMed:8093614).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12677 Genomic DNA Translation: BAA02180.1
BA000022 Genomic DNA Translation: BAA17411.1
PIRiB44425

Genome annotation databases

EnsemblBacteriaiBAA17411; BAA17411; BAA17411
KEGGisyn:slr2076

Similar proteinsi

Entry informationi

Entry nameiCH601_SYNY3
AccessioniPrimary (citable) accession number: Q05972
Secondary accession number(s): P73379
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 133 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

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