Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q05972

- CH601_SYNY3

UniProt

Q05972 - CH601_SYNY3

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

60 kDa chaperonin 1

Gene

groL1

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. protein refolding Source: UniProtKB-HAMAP
  2. response to stress Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 1UniRule annotation
Alternative name(s):
GroEL protein 1UniRule annotation
Protein Cpn60 1UniRule annotation
Gene namesi
Name:groL1UniRule annotation
Synonyms:cpn60-1, groEL-1UniRule annotation, groEL1UniRule annotation
Ordered Locus Names:slr2076
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed3 Publications
Chaini2 – 54154060 kDa chaperonin 1PRO_0000063575Add
BLAST

Proteomic databases

PaxDbiQ05972.
PRIDEiQ05972.

Expressioni

Inductioni

By stress conditions e.g. heat shock.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Binary interactionsi

WithEntry#Exp.IntActNotes
trxAP522314EBI-862119,EBI-862916

Protein-protein interaction databases

IntActiQ05972. 2 interactions.
STRINGi1148.slr2076.

Structurei

3D structure databases

ProteinModelPortaliQ05972.
SMRiQ05972. Positions 2-527.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0459.
HOGENOMiHOG000076290.
InParanoidiQ05972.
KOiK04077.
OMAiAMISANM.
OrthoDBiEOG6JDWBZ.
PhylomeDBiQ05972.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60.
InterProiIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view]
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q05972-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKSIIYNDE ARRALERGMD ILAEAVAVTL GPKGRNVVLE KKFGSPQIIN
60 70 80 90 100
DGITIAKEIE LEDHVENTGV SLIRQAASKT NDVAGDGTTT ATVLAHAIVK
110 120 130 140 150
EGLRNVAAGA NPISLKRGID KATDFLVARI KEHAQPVGDS KAIAQVGAIS
160 170 180 190 200
AGNDEEVGQM IANAMDKVGQ EGVISLEEGK SMTTELEITE GMRFDKGYIS
210 220 230 240 250
PYFVTDAERM EAVLEDPRIL ITDKKINLVQ DLVPILEQVA RQGKPLLIIA
260 270 280 290 300
EDIEKEALAT LVVNRLRGVL NVAAVKAPGF GDRRKQMLED IATLTGGQVI
310 320 330 340 350
SEDAGLKLES ATVDSLGSAR RINITKDNTT IVAEGNEAAV KSRCEQIRRQ
360 370 380 390 400
IEETDSSYDK EKLQERLAKL AGGVAVIKVG AATETEMKDR KLRLEDAINA
410 420 430 440 450
TKAAVEEGIV PGGGTTLAHL APQLEDWATG NLKDEELTGA LIVARALPAP
460 470 480 490 500
LKRIAENAGQ NGAVISERVK EKEFNVGYNA ASLEYVDMLA AGIVDPAKVT
510 520 530 540
RSALQNAASI AGMVLTTECI VVDKPEKEKA PAGAPGGDFD Y
Length:541
Mass (Da):57,653
Last modified:January 23, 2007 - v4
Checksum:i37E158A939CBFCB8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti12 – 121R → T AA sequence (PubMed:1346251)Curated
Sequence conflicti91 – 911A → D in BAA02180. (PubMed:8093614)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12677 Genomic DNA. Translation: BAA02180.1.
BA000022 Genomic DNA. Translation: BAA17411.1.
PIRiB44425.
RefSeqiNP_440731.1. NC_000911.1.
YP_005650790.1. NC_017277.1.
YP_007450614.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA17411; BAA17411; BAA17411.
GeneIDi954034.
KEGGisyn:slr2076.
PATRICi23838680. VBISynSp132158_0907.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12677 Genomic DNA. Translation: BAA02180.1 .
BA000022 Genomic DNA. Translation: BAA17411.1 .
PIRi B44425.
RefSeqi NP_440731.1. NC_000911.1.
YP_005650790.1. NC_017277.1.
YP_007450614.1. NC_020286.1.

3D structure databases

ProteinModelPortali Q05972.
SMRi Q05972. Positions 2-527.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q05972. 2 interactions.
STRINGi 1148.slr2076.

Proteomic databases

PaxDbi Q05972.
PRIDEi Q05972.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA17411 ; BAA17411 ; BAA17411 .
GeneIDi 954034.
KEGGi syn:slr2076.
PATRICi 23838680. VBISynSp132158_0907.

Phylogenomic databases

eggNOGi COG0459.
HOGENOMi HOG000076290.
InParanoidi Q05972.
KOi K04077.
OMAi AMISANM.
OrthoDBi EOG6JDWBZ.
PhylomeDBi Q05972.

Family and domain databases

Gene3Di 1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPi MF_00600. CH60.
InterProi IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view ]
PANTHERi PTHR11353. PTHR11353. 1 hit.
Pfami PF00118. Cpn60_TCP1. 1 hit.
[Graphical view ]
PRINTSi PR00298. CHAPERONIN60.
SUPFAMi SSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsi TIGR02348. GroEL. 1 hit.
PROSITEi PS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A second groEL-like gene, organized in a groESL operon is present in the genome of Synechocystis sp. PCC 6803."
    Lehel C., Los D.A., Wada H., Gyorgyei J., Horvath I., Kovacs E., Murata N., Vigh L.
    J. Biol. Chem. 268:1799-1804(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 2-26.
  2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.
  3. "Towards a proteome project of cyanobacterium Synechocystis sp. strain PCC6803: linking 130 protein spots with their respective genes."
    Sazuka T., Ohara O.
    Electrophoresis 18:1252-1258(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-21.
  4. "Heat shock protein synthesis of the cyanobacterium Synechocystis PCC 6803: purification of the GroEL-related chaperonin."
    Lehel C., Wada H., Kovacs E., Toroek Z., Gombos Z., Horvath I., Murata N., Vigh L.
    Plant Mol. Biol. 18:327-336(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-26.

Entry informationi

Entry nameiCH601_SYNY3
AccessioniPrimary (citable) accession number: Q05972
Secondary accession number(s): P73379
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: January 23, 2007
Last modified: November 26, 2014
This is version 110 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3