ID   ARLY_BUCCC              Reviewed;         460 AA.
AC   Q058D5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=Argininosuccinate lyase;
DE            Short=ASAL;
DE            EC=4.3.2.1;
DE   AltName: Full=Arginosuccinase;
GN   Name=argH; OrderedLocusNames=BCc_033;
OS   Buchnera aphidicola subsp. Cinara cedri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Buchnera.
OX   NCBI_TaxID=372461;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17038625; DOI=10.1126/science.1130441;
RA   Perez-Brocal V., Gil R., Ramos S., Lamelas A., Postigo M.,
RA   Michelena J.M., Silva F.J., Moya A., Latorre A.;
RT   "A small microbial genome: the end of a long symbiotic relationship?";
RL   Science 314:312-313(2006).
CC   -!- CATALYTIC ACTIVITY: 2-(N(omega)-L-arginino)succinate = fumarate +
CC       L-arginine.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-
CC       arginine from L-ornithine and carbamoyl phosphate: step 3/3.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the lyase 1 family. Argininosuccinate lyase
CC       subfamily.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000263; ABJ90514.1; -; Genomic_DNA.
DR   RefSeq; YP_802607.1; -.
DR   GeneID; 4440708; -.
DR   GenomeReviews; CP000263_GR; BCc_033.
DR   KEGG; bcc:BCc_033; -.
DR   OMA; Q058D5; MAEDLIF.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004056; F:argininosuccinate lyase activity; IEA:HAMAP.
DR   GO; GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro.
DR   HAMAP; MF_00006; -; 1.
DR   InterPro; IPR009049; Argininosuccinate_lyase.
DR   InterPro; IPR003031; D_crystallin.
DR   InterPro; IPR000362; Fumarate_lyase.
DR   PANTHER; PTHR11444:SF3; argH; 1.
DR   Pfam; PF00206; Lyase_1; 1.
DR   PRINTS; PR00145; DCRYSTALLIN.
DR   PRINTS; PR00149; FUMRATELYASE.
DR   TIGRFAMs; TIGR00838; argH; 1.
DR   PROSITE; PS00163; FUMARATE_LYASES; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome;
KW   Cytoplasm; Lyase.
FT   CHAIN         1    460       Argininosuccinate lyase.
FT                                /FTId=PRO_1000000455.
SQ   SEQUENCE   460 AA;  52510 MW;  3EF523898B223280 CRC64;
     MSLWGGRFTK ISNTEFDSFN NSLRIDHRLI KDDIKSSIAW SKILLDVQVL TKKEQKIIEN
     TLLSILKKNK NNFTKILSSN SEDIHSWLET TVINTIGDLG KKLYTGRSRN DQIATDLKLW
     CKRKSKKICR RIIQLQNDFL DNAYLHINTI IPGYTHLQRA QPITFSYWCL AYIEMLERDR
     LRILNLTQFL NSSPLGSGAI SGTSWEIDRK KLAFFMGFSE ITKNALDSVS DRDFILDILS
     AAAISMMHLS RFSEDLIFYN SGEANFIELS DSITSGSSLM PQKKNPDILE LIRAKCSSVY
     GSLFSMFSLL KGLPLSYNKD FQEDKNHLFS GLDIWEDCLK ISSLVLKNIK LKKSNCKKSA
     QLGYSNATEL AEYLVKKGIS FRDSHHITGK IVIASIKKNK CLEELDLLFL KKYCSKIESD
     VYQHLSLESC LNKKNSIGGV SNKQIKISLD QVKKRLSTFK
//