SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q058C8

- SYE_BUCCC

UniProt

Q058C8 - SYE_BUCCC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glutamate--tRNA ligase
Gene
gltX, BCc_042
Organism
Buchnera aphidicola subsp. Cinara cedri (strain Cc)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) By similarity.UniRule annotation

Catalytic activityi

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei241 – 2411ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glutamate-tRNA ligase activity Source: UniProtKB-HAMAP
  3. tRNA binding Source: InterPro

GO - Biological processi

  1. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBAPH372461:GHAJ-42-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate--tRNA ligase (EC:6.1.1.17)
Alternative name(s):
Glutamyl-tRNA synthetase
Short name:
GluRS
Gene namesi
Name:gltX
Ordered Locus Names:BCc_042
OrganismiBuchnera aphidicola subsp. Cinara cedri (strain Cc)
Taxonomic identifieri372461 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000669: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 474474Glutamate--tRNA ligaseUniRule annotation
PRO_1000001877Add
BLAST

Proteomic databases

PRIDEiQ058C8.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi372461.BCc_042.

Structurei

3D structure databases

ProteinModelPortaliQ058C8.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi9 – 1911"HIGH" regionUniRule annotation
Add
BLAST
Motifi238 – 2425"KMSKS" regionUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000252722.
KOiK01885.
OMAiHYIKELD.
OrthoDBiEOG6DRPF7.

Family and domain databases

Gene3Di1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00022_B. Glu_tRNA_synth_B.
InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00464. gltX_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q058C8-1 [UniParc]FASTAAdd to Basket

« Hide

MKIKTRFSPS PTGLLHMGGV RTALYSWLFA RKNNGSFILR IEDTDKNRVK    50
NNSVQDILYG LRYLQLNWDE GPFFQSNRIN IYKNIILFML KKGIAYKCYC 100
SKNRLDKLRK NQILNKKKPK YDNKCRNKNF FLKKSNIPYV IRFKNPTKGL 150
VEFRDMIRGK ISISNKELDD LVIQRSNGMP TYNFCVVVDD WQMNITHIIR 200
GEDHIHNTPR QINLLSSLNA YIPQYAHTSM ILDKKRKKLS KRCSSYSIIN 250
YINNGFIPEA ILNYALQLGW SYKNQEIFSI NEMKNIFNIK YINKSPSIID 300
KKKFLWFNHY YLNNISFNLK YKYFFSYCKK NNIFFDKDVN ISGVIKDFLG 350
RHSTFKDFIQ TYDYFYKEIN ISNIKNIYLY NKLINITILK FLYKKFNLLN 400
NWDLKNILLI IKESILYFKI SFKEIAILIR IVITGKKQTP SISSIIFYIG 450
KKKFLLRIKN FLKYLQLNNS NFSK 474
Length:474
Mass (Da):56,540
Last modified:November 14, 2006 - v1
Checksum:i4A62292F1D55B43B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000263 Genomic DNA. Translation: ABJ90521.1.
RefSeqiWP_011672440.1. NC_008513.1.
YP_802614.1. NC_008513.1.

Genome annotation databases

EnsemblBacteriaiABJ90521; ABJ90521; BCc_042.
GeneIDi4440970.
KEGGibcc:BCc_042.
PATRICi21246021. VBIBucAph7855_0036.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000263 Genomic DNA. Translation: ABJ90521.1 .
RefSeqi WP_011672440.1. NC_008513.1.
YP_802614.1. NC_008513.1.

3D structure databases

ProteinModelPortali Q058C8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 372461.BCc_042.

Proteomic databases

PRIDEi Q058C8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ90521 ; ABJ90521 ; BCc_042 .
GeneIDi 4440970.
KEGGi bcc:BCc_042.
PATRICi 21246021. VBIBucAph7855_0036.

Phylogenomic databases

eggNOGi COG0008.
HOGENOMi HOG000252722.
KOi K01885.
OMAi HYIKELD.
OrthoDBi EOG6DRPF7.

Enzyme and pathway databases

BioCyci BAPH372461:GHAJ-42-MONOMER.

Family and domain databases

Gene3Di 1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00022_B. Glu_tRNA_synth_B.
InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF48163. SSF48163. 1 hit.
TIGRFAMsi TIGR00464. gltX_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A small microbial genome: the end of a long symbiotic relationship?"
    Perez-Brocal V., Gil R., Ramos S., Lamelas A., Postigo M., Michelena J.M., Silva F.J., Moya A., Latorre A.
    Science 314:312-313(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Cc.

Entry informationi

Entry nameiSYE_BUCCC
AccessioniPrimary (citable) accession number: Q058C8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: September 3, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi