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Protein

Uncharacterized transcriptional regulatory protein YLR278C

Gene

YLR278C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi41 – 6828Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-32377-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized transcriptional regulatory protein YLR278C
Gene namesi
Ordered Locus Names:YLR278C
ORF Names:L8003.10
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLR278C.
SGDiS000004268. YLR278C.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13411341Uncharacterized transcriptional regulatory protein YLR278CPRO_0000115003Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1143 – 11431PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ05854.

PTM databases

iPTMnetiQ05854.

Interactioni

Protein-protein interaction databases

BioGridi31546. 43 interactions.
DIPiDIP-7433N.
IntActiQ05854. 4 interactions.
MINTiMINT-2491823.

Structurei

3D structure databases

ProteinModelPortaliQ05854.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi255 – 2617Poly-Asn
Compositional biasi873 – 88513Poly-SerAdd
BLAST
Compositional biasi918 – 94326Poly-AsnAdd
BLAST
Compositional biasi1231 – 12388Poly-Gln

Sequence similaritiesi

Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00730000112745.
HOGENOMiHOG000141995.
InParanoidiQ05854.
OMAiERMICVA.
OrthoDBiEOG092C0DDX.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q05854-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRPRKNVSQ EKIQQLKREL ELAGNRTDVL LQDKKGRSRS CLLCRRRKQR
60 70 80 90 100
CDHKLPSCTA CLKAGIKCVQ PSKYSSSTSN SNTNNNTPTA GTVPPTPHPV
110 120 130 140 150
IKRELQDSSI GAGAGAATSL NDMTIIKPIS TSNSNVDAGD ANEFRKTIKS
160 170 180 190 200
VTTNSNPNLM RQDKDQYTIF LEKKLKSLET LLDLSPGCNQ YNYELSQYKK
210 220 230 240 250
VSHLFSNNTS DYSRPNSSNM VILPLPSPSN KPLENTNNNG SNVNAATNDT
260 270 280 290 300
SASTNNINNN NAICQSASLL NDPLETLDFT KCIFAKYNLK KEFLMYDPIF
310 320 330 340 350
ELNEKLSRSF LDTFFTRLQF KYPILDEQEI YTFYDHYLHN KILIPPSSPA
360 370 380 390 400
TSSAAPPSNS HSYSEIEFHF LSGRMWLVFS ISAYLLMTTG KYKGFPPHRY
410 420 430 440 450
FSTAIRHITK CGLHLNYVQQ IELLTLLVLY IIRTDRDSLI LYDIIKDVMG
460 470 480 490 500
ISKKKLHLNQ WYPNDPFANK KLRLFWCVYL LERMICVAVG KPYTIKESEI
510 520 530 540 550
NLPLFNNDSF YTKGVHAAAP STNDHGVQFI NQSLKLRRIE SQFVETLQLL
560 570 580 590 600
KNDSRSVKQS IDQLPLVRKF FEDLEVWRKS YSTLDVKNFE NETLKLYYYR
610 620 630 640 650
SVRLLIQPYL EFFAPEDRLF RECQAAAGQI CQLYKIFHQK TLNGHSTPAV
660 670 680 690 700
HTVFVAGVTL IYCMWLARNF DDQRRKKLGD ASKHTRPLIS ASLFSTMDDL
710 720 730 740 750
RACSVCLYVM TERSNFARTF RDTFDQLMNA TVGNLIERCG PDSSELIFMA
760 770 780 790 800
SSVAKRTEPK NINDEANKAI SSGDTLHDSN SANAANLSNS NDKNISHNGG
810 820 830 840 850
MPPAVARIFG KGQAEEHAGF VENSQVDLAE QEKFKKKQGV LEKTSVPKSL
860 870 880 890 900
AHLLTKMDDR SRISNSSMSY TTSSSSSSSS SSSSSTLSFP SSQEKNLKIN
910 920 930 940 950
VNNDNNGMTI SSVNREHNNN HNNNNDNNNN NNNNNNNSNN NNNVNNNDNE
960 970 980 990 1000
SNSRSTTNNS CNNGNNSQYV RNNNVTMEND VERPIQDQYI VKKPTNQTEF
1010 1020 1030 1040 1050
DWQVFQQQAF LQQQLAQHNL QAYLSSLNTD TMTNRSPSKS SSISTASSHS
1060 1070 1080 1090 1100
DPIPIAMTQS PTPYPQTSNM LPQQHVSRPL PQQQREQPQQ HITSPQRFSE
1110 1120 1130 1140 1150
SNFTNQLNNG MINSNPLQSA IFSNHTSENK QLRDVEESNF STSPLRADYG
1160 1170 1180 1190 1200
NNIISSIPAS FTSNSIPVSV KQARNGSSSG DILFSNGAHD MINNISTWTN
1210 1220 1230 1240 1250
NSVLDALNSK SILQTIFPQS QEPSSLSMDK QQQQHQQQNM CSENNVTANN
1260 1270 1280 1290 1300
FQQTQNDPSY NRNLFMMSNQ EGVQYNLDET EKNGPKTQVE ANTSANLHFD
1310 1320 1330 1340
NVIPTVTNAD IRKKRSNWDN MMTSGPVEDF WTINDDYGFL T
Length:1,341
Mass (Da):151,279
Last modified:November 1, 1997 - v1
Checksum:i94201F3964500EEF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17243 Genomic DNA. Translation: AAB67326.1.
U17245 Genomic DNA. Translation: AAB67370.1.
BK006945 Genomic DNA. Translation: DAA09591.1.
PIRiS50366.
RefSeqiNP_013380.1. NM_001182165.1.

Genome annotation databases

EnsemblFungiiYLR278C; YLR278C; YLR278C.
GeneIDi850984.
KEGGisce:YLR278C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17243 Genomic DNA. Translation: AAB67326.1.
U17245 Genomic DNA. Translation: AAB67370.1.
BK006945 Genomic DNA. Translation: DAA09591.1.
PIRiS50366.
RefSeqiNP_013380.1. NM_001182165.1.

3D structure databases

ProteinModelPortaliQ05854.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31546. 43 interactions.
DIPiDIP-7433N.
IntActiQ05854. 4 interactions.
MINTiMINT-2491823.

PTM databases

iPTMnetiQ05854.

Proteomic databases

MaxQBiQ05854.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYLR278C; YLR278C; YLR278C.
GeneIDi850984.
KEGGisce:YLR278C.

Organism-specific databases

EuPathDBiFungiDB:YLR278C.
SGDiS000004268. YLR278C.

Phylogenomic databases

GeneTreeiENSGT00730000112745.
HOGENOMiHOG000141995.
InParanoidiQ05854.
OMAiERMICVA.
OrthoDBiEOG092C0DDX.

Enzyme and pathway databases

BioCyciYEAST:G3O-32377-MONOMER.

Miscellaneous databases

PROiQ05854.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYL278_YEAST
AccessioniPrimary (citable) accession number: Q05854
Secondary accession number(s): D6VYS5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: September 7, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1080 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.