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Q05815 (MCP_IIV6) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Major capsid protein

Short name=MCP
Alternative name(s):
P50
Gene names
Name:MCP
ORF Names:IIV-6 274L
OrganismInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus) [Reference proteome]
Taxonomic identifier176652 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostAcheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (striped riceborer) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]

Protein attributes

Sequence length467 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Major capsid protein that self assembles to form an icosahedral capsid with a T=147 symmetry. Represents around 50% of the total virion protein mass.

Subunit structure

Homotrimer Probable.

Subcellular location

Virion Potential.

Sequence similarities

Belongs to the NCLDV major capsid protein family.

Ontologies

Keywords
   Cellular componentCapsid protein
Virion
   Developmental stageLate protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentviral capsid

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionstructural molecule activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 467467Major capsid protein
PRO_0000222381

Experimental info

Sequence conflict3281S → Y Ref.1
Sequence conflict3311I → L Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q05815 [UniParc].

Last modified January 23, 2002. Version 2.
Checksum: 5A81E1E79D3B41A6

FASTA46751,322
        10         20         30         40         50         60 
MSISSSNVTS GFIDIATKDE IEKYMYGGKT STAYFVRETR KATWFTQVPV SLTRANGSAN 

        70         80         90        100        110        120 
FGSEWSASIS RAGDYLLYTW LRVRIPSVTL LSTNQFGANG RIRWCRNFMH NLIRECSITF 

       130        140        150        160        170        180 
NDLVAARFDH YHLDFWAAFT TPASKAVGYD NMIGNVSALI QPQPVPVAPA TVSLPEADLN 

       190        200        210        220        230        240 
LPLPFFFSRD SGVALPTAAL PYNEMRINFQ FHDWQRLLIL DNIAAVASQT VVPVVGATSD 

       250        260        270        280        290        300 
IATAPVLHHG TVWGNYAIVS NEERRRMGCS VRDILVEQVQ TAPRHVWNPT TNDAPNYDIR 

       310        320        330        340        350        360 
FSHAIKALFF AVRNTTFSNQ PSNYTTASPV ITSTTVILEP STGAFDPIHH TTLIYENTNR 

       370        380        390        400        410        420 
LNHMGSDYFS LVNPWYHAPT IPGLTGFHEY SYSLAFNEID PMGSTNYGKL TNISIVPTAS 

       430        440        450        460 
PAAKVGAAGT GPAGSGQNFP QTFEFIVTAL NNNIIRISGG ALGFPVL 

« Hide

References

« Hide 'large scale' references
[1]"Identification of the gene encoding the major capsid protein of insect iridescent virus type 6 by polymerase chain reaction."
Stohwasser R., Raab K., Schnitzler P., Janssen W., Darai G.
J. Gen. Virol. 74:873-879(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
Jakob N.J., Mueller K., Bahr U., Darai G.
Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
[4]"The capsid proteins of a large, icosahedral dsDNA virus."
Yan X., Yu Z., Zhang P., Battisti A.J., Holdaway H.A., Chipman P.R., Bajaj C., Bergoin M., Rossmann M.G., Baker T.S.
J. Mol. Biol. 385:1287-1299(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY CRYO-ELECTRON MICROSCOPY OF THE CAPSID.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF303741 Genomic DNA. Translation: AAK82135.1.
PIRJQ2215.
RefSeqNP_149737.1. NC_003038.1.

3D structure databases

ProteinModelPortalQ05815.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1733341.

Phylogenomic databases

ProtClustDBCLSP2511135.

Family and domain databases

Gene3D2.70.9.10. 1 hit.
2.70.9.20. 1 hit.
InterProIPR016114. ASFV_p72.
IPR016111. Hexon_subdom4.
IPR007542. Virus_major_coat_C.
IPR016112. VP_dsDNA_II.
[Graphical view]
PfamPF04451. Capsid_NCLDV. 1 hit.
[Graphical view]
SUPFAMSSF49749. SSF49749. 2 hits.
ProtoNetSearch...

Entry information

Entry nameMCP_IIV6
AccessionPrimary (citable) accession number: Q05815
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: January 23, 2002
Last modified: October 16, 2013
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families