Reviewed, UniProtKB/Swiss-Prot Q057S1 (SYR_BUCCC)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	BCc_152

Organism

Buchnera aphidicola subsp. Cinara cedri [Complete proteome] [HAMAP]

Taxonomic identifier

372461 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	571 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 571	571	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_1000017996
Regions
	Motif	122 – 132	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q057S1-1 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: C6AFCC0856C9BEB5	FASTA	571	67,427
	10 20 30 40 50 60 MNIQKFLKKK IKKICIKLGL PENFNPIIQK NIKKKNIDYQ INGIIKLKKK KSNYHYKLAK 70 80 90 100 110 120 KISYYMNKSK IYKKISISKP GFINITLDSN WICTNINNMF IAKNFNISFK KPKKIIIDYS 130 140 150 160 170 180 SPNIAKEMHV GHLRSTILGD TTARILKFLG HNVIKQNHIG DWGIQFGMLI TQLKLESKIS 190 200 210 220 230 240 FKNIEKIYKK SYLNYKKNPI FFKKTKKNVV KLQKKDKKCI YIWKKIVKKS IKKNNKVYKK 250 260 270 280 290 300 LNVSLKKKDI RGESFYNFML PGIISDLKKK KIAVNYQGCV IVYLKNFKNR LGKKMGVVIQ 310 320 330 340 350 360 KKDGAFLYTT TDIACLKYRC KTLKADRIIY YIDNRQKQHL LQIWNIAKKA KYFTKKILLE 370 380 390 400 410 420 HHSFGMILHK NKKPFKTRNG DTIKLIKLLN KGVTKAKEKI KKKNRKIKKK ELKKIAHNIG 430 440 450 460 470 480 IGAIKYFDLS KKRKLDYIFD WDKMLSLEGN TAPYIQYAYI RIKSIIKKNT TIFQNDKYKI 490 500 510 520 530 540 NIFTSFERQL IFSIFQFEEI IHILEKKGTP HLMCNYLYDL SGKFSKFYEN CSILNAKEKH 550 560 570 IKISRIKLSI LTSKIIKKCL YFLGIKTVSK M

References

[1]	"A small microbial genome: the end of a long symbiotic relationship?" Perez-Brocal V., Gil R., Ramos S., Lamelas A., Postigo M., Michelena J.M., Silva F.J., Moya A., Latorre A. Science 314:312-313(2006) [PubMed: 17038625] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000263 Genomic DNA. Translation: ABJ90628.1.
RefSeq	YP_802721.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4440620.
GenomeReviews	Gene locus BCc_152 in contig CP000263_GR.
KEGG	bcc:BCc_152.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	Q057S1. YNDDLQP.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_BUCCC

Accession

Primary (citable) accession number: Q057S1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 14, 2006
Last modified:	June 16, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)