Q057R4 (RNC_BUCCC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease 3
EC=3.1.26.3

Alternative name(s):
Ribonuclease III
Short name=RNase III

Gene names

Name:	rnc
Ordered Locus Names:	BCc_163

Organism

Buchnera aphidicola subsp. Cinara cedri (strain Cc) [Complete proteome] [HAMAP]

Taxonomic identifier

372461 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	226 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity. HAMAP MF_00104
Catalytic activity	Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP MF_00104
Subcellular location	Cytoplasm By similarity HAMAP MF_00104.
Sequence similarities	Contains 1 DRBM (double-stranded RNA-binding) domain. Contains 1 RNase III domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	RNA-binding
Molecular function	Endonuclease Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	RNA processing Inferred from electronic annotation. Source: InterPro rRNA catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	double-stranded RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease III activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 226	226	Ribonuclease 3 HAMAP MF_00104		PRO_1000075731
Regions
	Domain	6 – 128	123	RNase III
	Domain	155 – 225	71	DRBM

Sequences

	Sequence		Length	Mass (Da)
	Q057R4 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 0C88BF51C2CB931E	FASTA	226	25,705
	10 20 30 40 50 60 MNPIVMKKLQ KFIGYTFTNI TLLKHALTHR SASSQHNERL EFLGDSILSF IIAKALYHHF 70 80 90 100 110 120 PKMNEGGMSR MRATLVRGNT LAEIATEFSL GKYLQLGQGE KKSGGFKRES ILANAIEAII 130 140 150 160 170 180 ASIFLDSNIY TVERIILYWY KNRFKKMNPT GTKKDPKTRL QEYLQSKHFS LPIYSIGQIY 190 200 210 220 GEAHNQIFTI YCKIDGLSEL LIGIGASRRK AEQDAAQNAL IRLEVE

References

[1]

"A small microbial genome: the end of a long symbiotic relationship?" Perez-Brocal V., Gil R., Ramos S., Lamelas A., Postigo M., Michelena J.M., Silva F.J., Moya A., Latorre A. Science 314:312-313(2006) [PubMed: 17038625] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Cc.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000263 Genomic DNA. Translation: ABJ90635.1.
RefSeq	YP_802728.1. NC_008513.1.
3D structure databases
ProteinModelPortal	Q057R4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q057R4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000001362; EBBUCP00000001272; EBBUCG00000001362.
GeneID	4441010.
GenomeReviews	Gene locus BCc_163 in contig CP000263_GR.
KEGG	bcc:BCc_163.
PATRIC	21246269. VBIBucAph7855_0155.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0571.
GeneTree	EBGT00050000008067.
HOGENOM	HBG744556.
OMA	ALTHKSF.
Enzyme and pathway databases
BioCyc	BAPH372461:BCC_163-MONOMER.
Family and domain databases
HAMAP	MF_00104. RNase_III. [Tree]
InterPro	IPR001159. Ds-RNA-bd. IPR014720. dsRNA-bd-like. IPR000999. RNase_III. IPR011907. RNase_III_bac. [Graphical view]
Gene3D	G3DSA:3.30.160.20. dsRNA-bd-like. 1 hit. G3DSA:1.10.1520.10. RNase_III. 1 hit.
KO	K03685.
PANTHER	PTHR11207. PTHR11207. 1 hit.
Pfam	PF00035. dsrm. 1 hit. PF00636. Ribonuclease_3. 1 hit. [Graphical view]
SMART	SM00358. DSRM. 1 hit. SM00535. RIBOc. 1 hit. [Graphical view]
SUPFAM	SSF69065. RNase_III. 1 hit.
TIGRFAMs	TIGR02191. RNaseIII. 1 hit.
PROSITE	PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNC_BUCCC

Accession

Primary (citable) accession number: Q057R4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	November 14, 2006
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program