ID   K6PF_BUCCC              Reviewed;         320 AA.
AC   Q057P0;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=6-phosphofructokinase;
DE            Short=Phosphofructokinase;
DE            EC=2.7.1.11;
DE   AltName: Full=Phosphohexokinase;
GN   Name=pfkA; OrderedLocusNames=BCc_187;
OS   Buchnera aphidicola subsp. Cinara cedri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Buchnera.
OX   NCBI_TaxID=372461;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17038625; DOI=10.1126/science.1130441;
RA   Perez-Brocal V., Gil R., Ramos S., Lamelas A., Postigo M.,
RA   Michelena J.M., Silva F.J., Moya A., Latorre A.;
RT   "A small microbial genome: the end of a long symbiotic relationship?";
RL   Science 314:312-313(2006).
CC   -!- CATALYTIC ACTIVITY: ATP + D-fructose 6-phosphate = ADP + D-
CC       fructose 1,6-bisphosphate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 3/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the phosphofructokinase family.
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DR   EMBL; CP000263; ABJ90659.1; -; Genomic_DNA.
DR   RefSeq; YP_802752.1; -.
DR   GeneID; 4440798; -.
DR   GenomeReviews; CP000263_GR; BCc_187.
DR   KEGG; bcc:BCc_187; -.
DR   OMA; Q057P0; DTCLNTV.
DR   GO; GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
DR   GO; GO:0003872; F:6-phosphofructokinase activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR   HAMAP; MF_00339; -; 1.
DR   InterPro; IPR012003; ATP_PFK_prok.
DR   InterPro; IPR000023; Phosphofructokinase.
DR   InterPro; IPR015912; Phosphofructokinase_CS.
DR   Pfam; PF00365; PFK; 1.
DR   PIRSF; PIRSF000532; ATP_PFK_prok; 1.
DR   PRINTS; PR00476; PHFRCTKINASE.
DR   ProDom; PD000707; Ppfruckinase; 1.
DR   PROSITE; PS00433; PHOSPHOFRUCTOKINASE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase;
KW   Magnesium; Metal-binding; Nucleotide-binding; Transferase.
FT   CHAIN         1    320       6-phosphofructokinase.
FT                                /FTId=PRO_1000059749.
FT   NP_BIND      22     26       ATP (By similarity).
FT   NP_BIND     155    159       ATP (By similarity).
FT   NP_BIND     172    188       ATP (By similarity).
FT   ACT_SITE    128    128       Proton acceptor (By similarity).
FT   METAL       186    186       Magnesium; via carbonyl oxygen (By
FT                                similarity).
FT   METAL       188    188       Magnesium (By similarity).
FT   BINDING     163    163       Substrate (By similarity).
FT   BINDING     244    244       Substrate (By similarity).
FT   BINDING     250    250       Substrate (By similarity).
FT   BINDING     253    253       Substrate (By similarity).
SQ   SEQUENCE   320 AA;  35450 MW;  164259B6B644A758 CRC64;
     MIKKIGILTS GGDSPGMNAI IRSVVCTALN HNIEVKGIYN GFLGLYNNDM KLLKYSHVAN
     LLNQGGTILG SSRFLEFKLE KTRKIAIKNI YKRKIDCLII IGGDGSYKAA NFLTNMGVPC
     IGIPGTIDND VSGTDYTVGY FTALETVVDA IDKLRDTSAS HHRISIIEIM GRYCGDLTLS
     AAIAGGCEFI VIPEIIYQKE LLLLEIQKSI KKGNKHSIVA ITEHICDVNK LAKYIQKKTF
     KETRATILGH IQRGGKPVAY DRILASRMGI YAIQLLLKGY KGQCIGVINN KIVHHNINYA
     LKNMKKIFKK DLLNSIKKIY
//