Unreviewed, UniProtKB/TrEMBL Q05759 (Q05759_RAT)

Names and origin

Protein names

Submitted name:
    CAMP-dependent protein kinase catalytic subunit EMBL CAA37350.1

Gene names

Name:

Prkacb RGD 1310574

Organism

Rattus norvegicus (Rat) EMBL CAA37350.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	334 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. Spearmint SPM000961
Sequence similarities	Belongs to the protein kinase superfamily. RuleBase RU000305V3

Ontologies

Keywords
Ligand	ATP-binding Spearmint SPM000961 RuleBase RU000304V2 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Spearmint SPM000961 RuleBase RU000305V3 Transferase
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	334	1	EMBL CAA37350.1

Sequences

	Sequence		Length	Mass (Da)
	Q05759-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 116F131F6F5DE052	FASTA	334	39,021
	10 20 30 40 50 60 EFLSKAKEDF LRKWENPPPS NAGLEDFERK KTLGTGSFGR VMLVKHKATE QYYAMKILDK 70 80 90 100 110 120 QKVVKLKQIE HTLNEKRILQ AVEFPFLVGL EYSFKDNSNL YMVMEYVPGG EMFSHLRRIG 130 140 150 160 170 180 RFSEPHARFY AAQIVLTFEY LHSLDLIYRD LKPENLLIDH QGYIQVTDFG FAKRVKGRTW 190 200 210 220 230 240 TFCGTPEYLA PEIILSKGYN KAVDWWALGV LIYEMAAGYP PFFADQPIQI YEKIVAGKVR 250 260 270 280 290 300 FPSHFSSDLK DLLRNLLQVD LTKRFGNLKD GVNDIKNHKW FATTEWIAIY PRKVEAPFIP 310 320 330 KFKGFGDTSN FDDYEEEEIR VRITEKCGKE FSEF

References

[1]

"Isolation of a complementary DNA encoding the catalytic subunit of protein kinase A and studies on the expression of this sequence in rat hepatomas and regenerating liver." Roth J.S., Hsieh L.L., Peraino C., Weinstein I.B. Cancer Res. 50:1675-1680(1990) [PubMed: 2306720] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X53261 mRNA. Translation: CAA37350.1.
IPI	IPI00560492.
PIR	A60543.
UniGene	Rn.202491
3D structure databases
HSSP	HSSP built from PDB template 1CTP based on UniProtKB P36887.
SMR	Q05759. Positions 1-334.
ModBase	Search...
Protein-protein interaction databases
STRING	Q05759.
Genome annotation databases
Ensembl	ENSRNOT00000045967; ENSRNOP00000043572; ENSRNOG00000004978; Rattus norvegicus. [Genome view] ENSRNOT00000066735; ENSRNOP00000060614; ENSRNOG00000004978; Rattus norvegicus. [Genome view] ENSRNOT00000068739; ENSRNOP00000062228; ENSRNOG00000004978; Rattus norvegicus. [Genome view]
Phylogenomic databases
HOVERGEN	Q05759.
Gene expression databases
ArrayExpress	Q05759.
Genevestigator	Q05759.
Family and domain databases
InterPro	IPR000961. AGC-kinase_C. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_prot_kinase-like_dom. IPR008271. Ser/Thr_prot_kinase_AS. IPR002290. Ser/Thr_prot_kinase_dom. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
ProDom	PD000001. Prot_kinase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00133. S_TK_X. 1 hit. SM00220. S_TKc. 1 hit. [Graphical view]
PROSITE	PS51285. AGC_KINASE_CTER. 1 hit. PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q05759_RAT

Accession

Primary (citable) accession number: Q05759

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	November 3, 2009
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)