Q05759 (Q05759_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CAMP-dependent protein kinase catalytic subunit EMBL CAA37350.1

Gene names

Name:

Prkacb RGD 1310574

Organism

Rattus norvegicus (Rat) EMBL CAA37350.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	334 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. SAAS SAAS000961
Sequence similarities	Contains 1 AGC-kinase C-terminal domain. SAAS SAAS000961

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 SAAS SAAS000961 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase SAAS SAAS000961 Transferase
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	334	1	EMBL CAA37350.1

Sequences

	Sequence		Length	Mass (Da)
	Q05759 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 116F131F6F5DE052	FASTA	334	39,021
	10 20 30 40 50 60 EFLSKAKEDF LRKWENPPPS NAGLEDFERK KTLGTGSFGR VMLVKHKATE QYYAMKILDK 70 80 90 100 110 120 QKVVKLKQIE HTLNEKRILQ AVEFPFLVGL EYSFKDNSNL YMVMEYVPGG EMFSHLRRIG 130 140 150 160 170 180 RFSEPHARFY AAQIVLTFEY LHSLDLIYRD LKPENLLIDH QGYIQVTDFG FAKRVKGRTW 190 200 210 220 230 240 TFCGTPEYLA PEIILSKGYN KAVDWWALGV LIYEMAAGYP PFFADQPIQI YEKIVAGKVR 250 260 270 280 290 300 FPSHFSSDLK DLLRNLLQVD LTKRFGNLKD GVNDIKNHKW FATTEWIAIY PRKVEAPFIP 310 320 330 KFKGFGDTSN FDDYEEEEIR VRITEKCGKE FSEF

References

[1]	"Isolation of a complementary DNA encoding the catalytic subunit of protein kinase A and studies on the expression of this sequence in rat hepatomas and regenerating liver." Roth J.S., Hsieh L.L., Peraino C., Weinstein I.B. Cancer Res. 50:1675-1680(1990) [PubMed: 2306720] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X53261 mRNA. Translation: CAA37350.1.
IPI	IPI00948594.
PIR	A60543.
UniGene	Rn.202491.
3D structure databases
HSSP	HSSP built from PDB template 1CTP based on UniProtKB P36887.
ProteinModelPortal	Q05759.
ModBase	Search...
Protein-protein interaction databases
STRING	Q05759.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
RGD	1310574. Prkacb.
Phylogenomic databases
GeneTree	ENSGT00550000074358.
HOVERGEN	HBG108317.
InParanoid	Q05759.
Gene expression databases
ArrayExpress	Q05759.
Genevestigator	Q05759.
Family and domain databases
InterPro	IPR000961. AGC-kinase_C. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_kinase-like_dom. IPR008271. Ser/Thr_kinase_AS. IPR002290. Ser/Thr_kinase_dom. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00133. S_TK_X. 1 hit. SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS51285. AGC_KINASE_CTER. 1 hit. PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q05759_RAT

Accession

Primary (citable) accession number: Q05759

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	November 16, 2011
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)