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Q056Z3 (AROB_BUCCC) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:BCc_352
OrganismBuchnera aphidicola subsp. Cinara cedri (strain Cc) [Complete proteome] [HAMAP]
Taxonomic identifier372461 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3673673-dehydroquinate synthase HAMAP MF_00110
PRO_1000094467

Sequences

Sequence LengthMass (Da)Tools
Q056Z3 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: B1E7F3A8C661F173

FASTA36742,103
        10         20         30         40         50         60 
MIETIHVNLN NYSYNIYIGE YIFNNMFISS IFLKNKNNVL ITNKKIEKKI LKNKNQYFYK 

        70         80         90        100        110        120 
ILNKIHYFSI NDGENYKNLY EVEKIISFLL NNLYGRDLNL IALGGGVIGD ITGFVASIFQ 

       130        140        150        160        170        180 
RGVNFFQIPT TLLSQVDASI GGKTGVNHIL GKNMIGSFWQ PKGVFIDIKF LSTLPKKELL 

       190        200        210        220        230        240 
SGIAEIIKYA IVFDKIFFIW LENNLFKVLN LQKKELLYCI KKCCELKVKI IENDEKEIGN 

       250        260        270        280        290        300 
RVFLNLGHSF AHAIETFTGY GKWLHGNAVS VGIIMSSYLS FYLKYLKKSE LLNIINIFNN 

       310        320        330        340        350        360 
IGLPIIGPST MLPLDYLKLM MRDKKVINKN LRLVIPVSIG KVKLISSIKE NILLDSITAC 


QERRFFS

« Hide

References

[1]"A small microbial genome: the end of a long symbiotic relationship?"
Perez-Brocal V., Gil R., Ramos S., Lamelas A., Postigo M., Michelena J.M., Silva F.J., Moya A., Latorre A.
Science 314:312-313(2006) [PubMed: 17038625] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Cc.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000263 Genomic DNA. Translation: ABJ90806.1.
RefSeqYP_802899.1. NC_008513.1.

3D structure databases

ProteinModelPortalQ056Z3.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ056Z3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBUCT00000001507; EBBUCP00000001417; EBBUCG00000001507.
GeneID4440736.
GenomeReviewsGene locus BCc_352 in contig CP000263_GR.
KEGGbcc:BCc_352.
PATRIC21246651. VBIBucAph7855_0332.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
GeneTreeEBGT00050000008095.
HOGENOMHBG632303.
OMATERMISD.

Enzyme and pathway databases

BioCycBAPH372461:BCC_352-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_BUCCC
AccessionPrimary (citable) accession number: Q056Z3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 14, 2006
Last modified: January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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