Q056W4 (Q056W4_BUCCC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ketol-acid reductoisomerase EMBL ABJ90835.1
EC=1.1.1.86 EMBL ABJ90835.1

Gene names

Name:	ilvC EMBL ABJ90835.1
Ordered Locus Names:	BCc_388

Organism

Buchnera aphidicola subsp. Cinara cedri (strain Cc) [Complete proteome] [HAMAP]

Taxonomic identifier

372461 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	490 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP+ = (S)-2-hydroxy-2-ethyl-3-oxobutanoate + NADPH. SAAS SAAS014359 (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH. SAAS SAAS014359
Pathway	Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4. SAAS SAAS014359 Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4. SAAS SAAS014359

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Branched-chain amino acid biosynthesis SAAS SAAS014359
Ligand	NADP SAAS SAAS014359
Molecular function	Isomerase EMBL ABJ90835.1 Oxidoreductase SAAS SAAS014359 EMBL ABJ90835.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	branched chain family amino acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW ketol-acid reductoisomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q056W4 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 07D10733AECF50E1	FASTA	490	55,732
	10 20 30 40 50 60 MKNFFNKLSF REKLIELNTG FLMNSNEFLH SKKKLKNKKI VIIGCGAQGL NQGLNLRDSG 70 80 90 100 110 120 FNVTYALRKK SIENKSISWK NAIREKFFVD TYENLVPSAD LVINLTPDKQ HSVVVKKLQK 130 140 150 160 170 180 LMKKNSVLGY SHGFNIVEIG EEIRSDITVI MVAPKCPGTE VRKEFLKGFG VPTLIAVHKK 190 200 210 220 230 240 NDPKKIGLDI AKAWATGLGS HKAGILKSSF IAEVKSDLMG EQTILCGMLQ ACSLVCFNHL 250 260 270 280 290 300 IEKGYSSDFS ATLLQFGWEK LAECMKEGGI TLLFNRLSIS SKIRAYKLSI VLKSLLRPLF 310 320 330 340 350 360 CLHMDNIISG DFSKNMIADW NNSDIQLYNW RKKLKKSHFE NSNLYSNRKI LDHEYFEKCT 370 380 390 400 410 420 LMAAMLKDLK LCINTGITSA SAYYESLHEL PLIANTISRK RLYEMNLVIS DTAEYGSHLF 430 440 450 460 470 480 SERAISILNK FLKSINSDDL GETIRDTNIT NSELLYVNDM IENHHIERIG KKLRLYMTNM 490 KRTALHDCKN

References

[1]

"A small microbial genome: the end of a long symbiotic relationship?" Perez-Brocal V., Gil R., Ramos S., Lamelas A., Postigo M., Michelena J.M., Silva F.J., Moya A., Latorre A. Science 314:312-313(2006) [PubMed: 17038625] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Cc.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000263 Genomic DNA. Translation: ABJ90835.1.
RefSeq	YP_802928.1. NC_008513.1.
3D structure databases
ProteinModelPortal	Q056W4.
SMR	Q056W4. Positions 3-485.
ModBase	Search...
Protein-protein interaction databases
STRING	Q056W4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000001494; EBBUCP00000001404; EBBUCG00000001494.
GeneID	4440870.
GenomeReviews	Gene locus BCc_388 in contig CP000263_GR.
KEGG	bcc:BCc_388.
PATRIC	21246725. VBIBucAph7855_0362.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0059.
GeneTree	EBGT00050000007925.
HOGENOM	HBG297205.
OMA	EKHMDDI.
ProtClustDB	PRK05225.
Family and domain databases
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR013023. AcH_isomrdctse. IPR000506. AcH_isomrdctse_C. IPR013328. DH_multihelical. IPR013116. IlvN. IPR014359. KetolA_reductoisomerase_bac. [Graphical view]
Gene3D	G3DSA:1.10.1040.10. Opine_DH. 2 hits.
KO	K00053.
PANTHER	PTHR21371. AcH_isomrdctse. 1 hit. PTHR21371:SF2. PTHR21371:SF2. 1 hit.
Pfam	PF01450. IlvC. 2 hits. PF07991. IlvN. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 2 hits.
TIGRFAMs	TIGR00465. IlvC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q056W4_BUCCC

Accession

Primary (citable) accession number: Q056W4

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)