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Q05650 (GLNA_BUTFI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine synthetase

Short name=GS
EC=6.3.1.2
Alternative name(s):
Glutamate--ammonia ligase
Gene names
Name:glnA
OrganismButyrivibrio fibrisolvens
Taxonomic identifier831 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesLachnospiraceaeButyrivibrio

Protein attributes

Sequence length700 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Subunit structure

Homohexamer.

Sequence similarities

Belongs to the glutamine synthetase family. Type 3 subfamily.

Ontologies

Keywords
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
Gene Ontology (GO)
   Biological_processnitrogen compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamate-ammonia ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 700700Glutamine synthetase
PRO_0000153278

Sequences

Sequence LengthMass (Da)Tools
Q05650 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 32DDD0FA10B542E7

FASTA70078,541
        10         20         30         40         50         60 
MIEASKLTTE FGSLVFNDKI MKERLPKDIY KAVHKTIEKE PHLEPGCSYS CSSNHEGVGN 

        70         80         90        100        110        120 
REQCYHFTPP GSSPMTGLTA EKHDSFISPT EDGRSSWSSQ EKSWLRANLM HQASQWWSSC 

       130        140        150        160        170        180 
HNSSMRGYQH GILHHHAFIK DGSLLLPTAF CSYGGEALDR DSLLRSMEAL SNEAVKMMRL 

       190        200        210        220        230        240 
LGYEDVNRVN TTIGSEQEYF LIDKDFYKKR KDLLLTGRTL IGAPASKGQE MEDHYFGVIK 

       250        260        270        280        290        300 
PKVSAYMHDL DEELWKLGIP AKTKHNEVAP SQHELAPVFE TANIAVDHNQ LTMEVMKKVA 

       310        320        330        340        350        360 
DKHNYACLLH EKPFEGVNGS GKHNNWSICT DTGINLLDPG KNPGENIPFL VFLMSVIAAV 

       370        380        390        400        410        420 
DEYAPILRLS VASAGNDHRL GGNEAPPAII SIFVGDELAE VLKAVEAGEA YKAAGKSQMT 

       430        440        450        460        470        480 
WEQQYFTFTK DNTDRNRTSP FAFTGNKFES DGGHSSVANG KYGPQHMQLQ KEVATLNAKL 

       490        500        510        520        530        540 
SAYSGDELKE KVKEVLKETL LAHKRVLFNG NGYTDEWVEE AAKRGLPNLK ALPDCMPYWI 

       550        560        570        580        590        600 
SDESIDLFTR HGIFTKEEIY SRYEILLENY SKSIHIESLT MQEMIRKDLT EGLVAYEKDL 

       610        620        630        640        650        660 
SKEIVQKKSL LDGDCCALEL GVLKSLDKSS AEMGKALSKL FEDTKKAEGM TEALETASYY 

       670        680        690        700 
ESTVLADMDE LRKYADEAEA LIPEKYLSYP TYGEMLFSLR 

« Hide

References

[1]"Cloning and nucleotide sequence of the Butyrivibrio fibrisolvens gene encoding a type III glutamine synthetase."
Goodman H.J., Woods D.R.
J. Gen. Microbiol. 139:1487-1493(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L08256 Unassigned DNA. Translation: AAA71923.1.
PIRI40596.

3D structure databases

ProteinModelPortalQ05650.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.30.590.10. 2 hits.
InterProIPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR022147. GSIII_N.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
PF12437. GSIII_N. 1 hit.
[Graphical view]
PROSITEPS00181. GLNA_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLNA_BUTFI
AccessionPrimary (citable) accession number: Q05650
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: February 19, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families