Reviewed, UniProtKB/Swiss-Prot Q05650 (GLNA_BUTFI)

Names and origin

Protein names

Recommended name:
    Glutamine synthetase
      Short name=GS
    EC=6.3.1.2
Alternative name(s):
    Glutamate--ammonia ligase

Gene names

Name:

glnA

Organism

Butyrivibrio fibrisolvens

Taxonomic identifier

831 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Lachnospiraceae › Butyrivibrio

Protein attributes

Sequence length	700 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.
Subunit structure	Homohexamer.
Sequence similarities	Belongs to the glutamine synthetase family. Type 3 subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glutamate-ammonia ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 700	700	Glutamine synthetase		PRO_0000153278

Sequences

	Sequence		Length	Mass (Da)
	Q05650-1 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 32DDD0FA10B542E7	FASTA	700	78,541
	10 20 30 40 50 60 MIEASKLTTE FGSLVFNDKI MKERLPKDIY KAVHKTIEKE PHLEPGCSYS CSSNHEGVGN 70 80 90 100 110 120 REQCYHFTPP GSSPMTGLTA EKHDSFISPT EDGRSSWSSQ EKSWLRANLM HQASQWWSSC 130 140 150 160 170 180 HNSSMRGYQH GILHHHAFIK DGSLLLPTAF CSYGGEALDR DSLLRSMEAL SNEAVKMMRL 190 200 210 220 230 240 LGYEDVNRVN TTIGSEQEYF LIDKDFYKKR KDLLLTGRTL IGAPASKGQE MEDHYFGVIK 250 260 270 280 290 300 PKVSAYMHDL DEELWKLGIP AKTKHNEVAP SQHELAPVFE TANIAVDHNQ LTMEVMKKVA 310 320 330 340 350 360 DKHNYACLLH EKPFEGVNGS GKHNNWSICT DTGINLLDPG KNPGENIPFL VFLMSVIAAV 370 380 390 400 410 420 DEYAPILRLS VASAGNDHRL GGNEAPPAII SIFVGDELAE VLKAVEAGEA YKAAGKSQMT 430 440 450 460 470 480 WEQQYFTFTK DNTDRNRTSP FAFTGNKFES DGGHSSVANG KYGPQHMQLQ KEVATLNAKL 490 500 510 520 530 540 SAYSGDELKE KVKEVLKETL LAHKRVLFNG NGYTDEWVEE AAKRGLPNLK ALPDCMPYWI 550 560 570 580 590 600 SDESIDLFTR HGIFTKEEIY SRYEILLENY SKSIHIESLT MQEMIRKDLT EGLVAYEKDL 610 620 630 640 650 660 SKEIVQKKSL LDGDCCALEL GVLKSLDKSS AEMGKALSKL FEDTKKAEGM TEALETASYY 670 680 690 700 ESTVLADMDE LRKYADEAEA LIPEKYLSYP TYGEMLFSLR

References

[1]	"Cloning and nucleotide sequence of the Butyrivibrio fibrisolvens gene encoding a type III glutamine synthetase." Goodman H.J., Woods D.R. J. Gen. Microbiol. 139:1487-1493(1993) [PubMed: 8103789] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	L08256 Unassigned DNA. Translation: AAA71923.1.
PIR	I40596.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	6.3.1.2. 1431.
Family and domain databases
InterPro	IPR008147. Gln_synt_beta. IPR014746. Gln_synth/guanido_kin_cat. IPR008146. Gln_synth_cat. [Graphical view]
Gene3D	G3DSA:3.30.590.10. ATP-gua_Ptrans. 1 hit.
Pfam	PF00120. Gln-synt_C. 1 hit. [Graphical view]
ProDom	PD001057. Gln_synt_C. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00180. GLNA_1. False negative. PS00181. GLNA_ATP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLNA_BUTFI

Accession

Primary (citable) accession number: Q05650

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	June 16, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)