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Q05624 (PTB_CLOB8) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate butyryltransferase

EC=2.3.1.19
Alternative name(s):
Phosphotransbutyrylase
Gene names
Name:ptb
Ordered Locus Names:Cbei_0203
OrganismClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum) [Complete proteome] [HAMAP]
Taxonomic identifier290402 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length302 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate.

Catalytic activity

Butanoyl-CoA + phosphate = CoA + butanoylphosphate.

Pathway

Lipid metabolism; butanoate metabolism.

Sequence similarities

Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processbutyrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionphosphate butyryltransferase activity

Inferred from direct assay PubMed 2317039. Source: CACAO

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 302302Phosphate butyryltransferase
PRO_0000179153

Sequences

Sequence LengthMass (Da)Tools
Q05624 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 52C3A7BFB187C1FF

FASTA30232,442
        10         20         30         40         50         60 
MSKNFDELLS RLKEVPTKKV AVAVAQDEPV LEAIKEATEN NIAQAILVGD KQQIHEIAKK 

        70         80         90        100        110        120 
INLDLSDYEI MDIKDPKKAT LEAVKLVSSG HADMLMKGLV DTATFLRSVL NKEVGLRTGK 

       130        140        150        160        170        180 
LMSHVAVFDV EGWDRLLFLT DAAFNTYPEF KDKVGMINNA VVVAHACGID VPRVAPICPV 

       190        200        210        220        230        240 
EVVNTSMQST VDAALLAKMS DRGQIKGCVI DGPFALDNAI SEEAAHHKGV TGSVAGKADI 

       250        260        270        280        290        300 
LLLPNIEAAN VMYKTLTYFS KSRNGGLLVG TSAPVILTSR ADSFETKVNS IALAALVAAR 


NK 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and sequence analysis of the genes encoding phosphotransbutyrylase and butyrate kinase from Clostridium acetobutylicum NCIMB 8052."
Oultram J.D., Burr I.D., Elmore M.J., Minton N.P.
Gene 131:107-112(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete sequence of Clostridium beijerinckii NCIMB 8052."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Tapia R., Brainard J., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Mikhailova N., Bennet G., Cann I., Chen J.-S., Contreras A.L., Jones D., Kashket E., Mitchell W., Stoddard S., Schwarz W., Qureshi N., Young M., Shi Z., Ezeji T., White B., Blaschek H., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51743 / NCIMB 8052.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L04468 Genomic DNA. Translation: AAA52080.1.
CP000721 Genomic DNA. Translation: ABR32393.1.
RefSeqYP_001307349.1. NC_009617.1.

3D structure databases

ProteinModelPortalQ05624.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290402.Cbei_0203.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR32393; ABR32393; Cbei_0203.
GeneID5291437.
KEGGcbe:Cbei_0203.
PATRIC19344246. VBICloBei69853_0208.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0280.
HOGENOMHOG000009438.
KOK00634.
OMASCAVASM.
OrthoDBEOG60GRZ3.
ProtClustDBPRK05805.

Enzyme and pathway databases

BioCycCBEI290402:GHL5-234-MONOMER.
UniPathwayUPA00863.

Family and domain databases

InterProIPR012147. P_Ac_Bu_trans.
IPR014079. Phosphate_butyryltransferase.
IPR002505. PTA_PTB.
[Graphical view]
PfamPF01515. PTA_PTB. 2 hits.
[Graphical view]
PIRSFPIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMsTIGR02706. P_butyryltrans. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTB_CLOB8
AccessionPrimary (citable) accession number: Q05624
Secondary accession number(s): A6LPW3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 13, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways