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Q05622

- GUNE_RUMFL

UniProt

Q05622 - GUNE_RUMFL

Protein

Endoglucanase E

Gene

celE

Organism
Ruminococcus flavefaciens
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Hydrolyzes both carboxymethylcellulose and xylan. Probably has a role in hydrolyzing oligosaccharides derived from cellulose, which are transported across the cell wall.

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei150 – 1501Proton donorBy similarity

    GO - Molecular functioni

    1. cellulase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW
    2. xylan catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation, Xylan degradation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endoglucanase E (EC:3.2.1.4)
    Short name:
    EGE
    Alternative name(s):
    Cellulase
    Endo-1,4-beta-glucanase E
    Gene namesi
    Name:celE
    OrganismiRuminococcus flavefaciens
    Taxonomic identifieri1265 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminococcus

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2929Sequence AnalysisAdd
    BLAST
    Chaini30 – 320291Endoglucanase EPRO_0000012253Add
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Signal

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q05622-1 [UniParc]FASTAAdd to Basket

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    MRKRITSMIT VISLTLCGTI GTYPHNANAS AKEAFEDISK RSECTKVFDN    50
    DNGTYTAYSN TAPIHYLNND EWKEIDNTLI EDSDDYYRNK DNSFNIYIPK 100
    EYSLGKNIKN PVIMNYDTFS LSTSITDIKM PDRPEEETFS EGVYADINNE 150
    VYTTIDNSAI AEGMKAALKK SASMATYHSI VEDIDLDIAV HNASVSESII 200
    INKLESLPET ITYSISVEDA IIKKTEDNRL QLIKDNEAVL ILSPFTISDS 250
    SENVNVMQVE YDLTESEEGY EVTLYPAETV NRMSSPVMPL SLGSEYSYDR 300
    PFSTVYNSQA SLHPSIIIIT 320
    Length:320
    Mass (Da):35,938
    Last modified:February 1, 1995 - v1
    Checksum:iDD5C549423405AFD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L03800 Genomic DNA. Translation: AAA26468.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L03800 Genomic DNA. Translation: AAA26468.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Transcriptional regulation of an endoglucanase and a cellodextrinase gene in Ruminococcus flavefaciens FD-1."
      Wang W., Reid S.J., Thomson J.A.
      J. Gen. Microbiol. 139:1219-1226(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: FD-1.

    Entry informationi

    Entry nameiGUNE_RUMFL
    AccessioniPrimary (citable) accession number: Q05622
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries

    External Data

    Dasty 3