BSC2

Functionⁱ

Miscellaneous

Present with 922 molecules/cell in log phase SD medium.1 Publication

Open reading frame exhibits genomic organization compatible with a translational readthrough-dependent mode of expression.

Enzyme and pathway databases

BioCycⁱ	YEAST:G3O-29841-MONOMER.

BioCycⁱ

YEAST:G3O-29841-MONOMER.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Bypass of stop codon protein 2
Gene namesⁱ	Name:BSC2 Ordered Locus Names:YDR275W
Organismⁱ	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifierⁱ	559292 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae
Proteomesⁱ	UP000002311 Componentⁱ: Chromosome IV

Organism-specific databases

EuPathDBⁱ	FungiDB:YDR275W.
Saccharomyces Genome Database More...SGDⁱ	S000002683. BSC2.

Subcellular locationⁱ

Lipid droplet
1 Publication
Manual assertion based on experiment inⁱ
- Ref.5
  "Global analysis of protein localization in budding yeast."
  Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
  Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
Membrane
1 Publication
Manual assertion based on experiment inⁱ
- Ref.5
  "Global analysis of protein localization in budding yeast."
  Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
  Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
; Single-pass membrane protein
1 Publication
Manual assertion based on experiment inⁱ
- Ref.5
  "Global analysis of protein localization in budding yeast."
  Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
  Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Note:

Punctate lipid particles.

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	68 – 88	HelicalSequence analysisAdd BLAST		21

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW
lipid particle Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Lipid droplet, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000064993	1 – 235	Bypass of stop codon protein 2Add BLAST		235

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	177	PhosphoserineCombined sources		1

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q05611.
PRIDEⁱ	Q05611.

PTM databases

iPTMnetⁱ	Q05611.

iPTMnetⁱ

Q05611.

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	32328. 89 interactors.
Database of interacting proteins More...DIPⁱ	DIP-5218N.
IntActⁱ	Q05611. 2 interactors.
Molecular INTeraction database More...MINTⁱ	MINT-510938.
STRINGⁱ	4932.YDR275W.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q05611.
SMRⁱ	Q05611.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

Database of Orthologous Groups More...OrthoDBⁱ	EOG092C4T2T.

OrthoDBⁱ

EOG092C4T2T.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q05611-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MFFFPKLRKL IGSTVIDHDT KNSSGKEEIM SNSRLALVII NHAFDKVLSL 
        60         70         80         90        100
TWHCGILSEI RSGLMLMFGI FQLMCSLGVI VLLLPIIILD AIDLFLYMCR 
       110        120        130        140        150
LLDYGCKLFH YNRSSLPVAD GKEKTSGPIS GKEEIVIDEE IINMLNESSE 
       160        170        180        190        200
SLINHTTAGL EYDISSGSVN KSRRLNSTST VTFVKQNKLV NERREDAYYE 
       210        220        230 
EEDDDFLSNP NYDKISLIEK SFTSRFEVAC EQKAA

Length:235

Mass (Da):26,582

Last modified:November 1, 1996 - v1

Checksum:ⁱ9987EE269A88CB12

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U51030 Genomic DNA. Translation: AAB64448.1. AY557736 Genomic DNA. Translation: AAS56062.1. BK006938 Genomic DNA. Translation: DAA12116.1.
PIRⁱ	S70132.
NCBI Reference Sequences More...RefSeqⁱ	NP_010561.1. NM_001180583.1.

Genome annotation databases

EnsemblFungiⁱ	YDR275W; YDR275W; YDR275W.
GeneIDⁱ	851868.
KEGGⁱ	sce:YDR275W.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U51030 Genomic DNA. Translation: AAB64448.1. AY557736 Genomic DNA. Translation: AAS56062.1. BK006938 Genomic DNA. Translation: DAA12116.1.
PIRⁱ	S70132.
NCBI Reference Sequences More...RefSeqⁱ	NP_010561.1. NM_001180583.1.

3D structure databases

ProteinModelPortalⁱ	Q05611.
SMRⁱ	Q05611.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	32328. 89 interactors.
Database of interacting proteins More...DIPⁱ	DIP-5218N.
IntActⁱ	Q05611. 2 interactors.
Molecular INTeraction database More...MINTⁱ	MINT-510938.
STRINGⁱ	4932.YDR275W.

PTM databases

iPTMnetⁱ	Q05611.

iPTMnetⁱ

Q05611.

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q05611.
PRIDEⁱ	Q05611.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblFungiⁱ	YDR275W; YDR275W; YDR275W.
GeneIDⁱ	851868.
KEGGⁱ	sce:YDR275W.

Organism-specific databases

EuPathDBⁱ	FungiDB:YDR275W.
Saccharomyces Genome Database More...SGDⁱ	S000002683. BSC2.

Phylogenomic databases

Database of Orthologous Groups More...OrthoDBⁱ	EOG092C4T2T.

OrthoDBⁱ

EOG092C4T2T.

Enzyme and pathway databases

BioCycⁱ	YEAST:G3O-29841-MONOMER.

BioCycⁱ

YEAST:G3O-29841-MONOMER.

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q05611.

PROⁱ

PR:Q05611.

Family and domain databases

ProtoNetⁱ	Search...

ProtoNetⁱ

Search...

Entry informationⁱ

Entry nameⁱ	BSC2_YEAST
Accessionⁱ	Q05611Primary (citable) accession number: Q05611 Secondary accession number(s): D6VSQ6
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
	Last sequence update:	November 1, 1996
	Last modified:	July 5, 2017
	This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Fungal Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
Yeast chromosome IV
Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q05611 (BSC2_YEAST)

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Bypass of stop codon protein 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ