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Protein

Bypass of stop codon protein 2

Gene

BSC2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-29841-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Bypass of stop codon protein 2
Gene namesi
Name:BSC2
Ordered Locus Names:YDR275W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR275W.
SGDiS000002683. BSC2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei68 – 8821HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Lipid droplet, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 235235Bypass of stop codon protein 2PRO_0000064993Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei177 – 1771PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ05611.

PTM databases

iPTMnetiQ05611.

Interactioni

Protein-protein interaction databases

BioGridi32328. 5 interactions.
DIPiDIP-5218N.
IntActiQ05611. 2 interactions.
MINTiMINT-510938.

Structurei

3D structure databases

ProteinModelPortaliQ05611.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiEOG7W6WXV.

Sequencei

Sequence statusi: Complete.

Q05611-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFFFPKLRKL IGSTVIDHDT KNSSGKEEIM SNSRLALVII NHAFDKVLSL
60 70 80 90 100
TWHCGILSEI RSGLMLMFGI FQLMCSLGVI VLLLPIIILD AIDLFLYMCR
110 120 130 140 150
LLDYGCKLFH YNRSSLPVAD GKEKTSGPIS GKEEIVIDEE IINMLNESSE
160 170 180 190 200
SLINHTTAGL EYDISSGSVN KSRRLNSTST VTFVKQNKLV NERREDAYYE
210 220 230
EEDDDFLSNP NYDKISLIEK SFTSRFEVAC EQKAA
Length:235
Mass (Da):26,582
Last modified:November 1, 1996 - v1
Checksum:i9987EE269A88CB12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U51030 Genomic DNA. Translation: AAB64448.1.
AY557736 Genomic DNA. Translation: AAS56062.1.
BK006938 Genomic DNA. Translation: DAA12116.1.
PIRiS70132.
RefSeqiNP_010561.1. NM_001180583.1.

Genome annotation databases

EnsemblFungiiYDR275W; YDR275W; YDR275W.
GeneIDi851868.
KEGGisce:YDR275W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U51030 Genomic DNA. Translation: AAB64448.1.
AY557736 Genomic DNA. Translation: AAS56062.1.
BK006938 Genomic DNA. Translation: DAA12116.1.
PIRiS70132.
RefSeqiNP_010561.1. NM_001180583.1.

3D structure databases

ProteinModelPortaliQ05611.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32328. 5 interactions.
DIPiDIP-5218N.
IntActiQ05611. 2 interactions.
MINTiMINT-510938.

PTM databases

iPTMnetiQ05611.

Proteomic databases

MaxQBiQ05611.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDR275W; YDR275W; YDR275W.
GeneIDi851868.
KEGGisce:YDR275W.

Organism-specific databases

EuPathDBiFungiDB:YDR275W.
SGDiS000002683. BSC2.

Phylogenomic databases

OrthoDBiEOG7W6WXV.

Enzyme and pathway databases

BioCyciYEAST:G3O-29841-MONOMER.

Miscellaneous databases

PROiQ05611.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
    Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.
    , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
    Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "Identification of stop codon readthrough genes in Saccharomyces cerevisiae."
    Namy O., Duchateau-Nguyen G., Hatin I., Hermann-Le Denmat S., Termier M., Rousset J.-P.
    Nucleic Acids Res. 31:2289-2296(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE NAME.
  5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  7. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiBSC2_YEAST
AccessioniPrimary (citable) accession number: Q05611
Secondary accession number(s): D6VSQ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: November 1, 1996
Last modified: June 8, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 922 molecules/cell in log phase SD medium.1 Publication
Open reading frame exhibits genomic organization compatible with a translational readthrough-dependent mode of expression.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.