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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene namesi
Name:dnaK
Ordered Locus Names:SCO3671
ORF Names:SCH44.11c
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 618618Chaperone protein DnaKPRO_0000078550Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei173 – 1731Phosphothreonine; by autocatalysisBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ05558.

Expressioni

Inductioni

By stress conditions e.g. heat shock (By similarity).By similarity

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO3671.

Structurei

3D structure databases

ProteinModelPortaliQ05558.
SMRiQ05558. Positions 1-505.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
InParanoidiQ05558.
KOiK04043.
OMAiEKMAPPQ.
OrthoDBiPOG091H01UE.
PhylomeDBiQ05558.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q05558-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARAVGIDLG TTNSVVSVLE GGEPTVITNA EGARTTPSVV AFAKNGEVLV
60 70 80 90 100
GEVAKRQAVT NVDRTIRSVK RHMGTDWKVN LDGKDFNPQQ ISAFVLQKLK
110 120 130 140 150
RDAESYLGEK VTDAVITVPA YFNDAERQAT KEAGEIAGLN VLRIVNEPTA
160 170 180 190 200
AALAYGLDKD EQVILVFDLG GGTFDVSLLE IGDGVVEVKA TNGDNNLGGD
210 220 230 240 250
DWDQRVVDYL VKQFQSGHGV DLAKDKMALQ RLREAAEKAK IELSSSTETT
260 270 280 290 300
INLPYITASA EGPLHLDEKL TRAQFQQLTS DLLERCKTPF HNVIKDAGIQ
310 320 330 340 350
LSEIDHVVLV GGSTRMPAVA ELVKELTGGK DANKGVNPDE VVAIGAALQA
360 370 380 390 400
GVLKGEVKDV LLLDVTPLSL GIETKGGIMT KLIERNTTIP TKRSEIFTTA
410 420 430 440 450
EDNQPSVQIQ VYQGEREIAA YNKKLGMFEL TGLPPAPRGV PQIEVAFDID
460 470 480 490 500
ANGIMHVTAK DLGTGKEQKM TVTGGSSLPK DEVDRMRQEA EKYAEEDHAR
510 520 530 540 550
REAAESRNQG EQLVYQTEKF LKDNEDKVPG EVKTEVESAV AELKEKLKGE
560 570 580 590 600
DTAEIRTATE KVAAVSQKLG QAMYADAQAA QAAGGEAPGA DAGAEGKGAD
610
DDVVDAEIVD DERKDGAA
Length:618
Mass (Da):66,270
Last modified:February 1, 1994 - v1
Checksum:i3735D39BD14A0511
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L46700 Genomic DNA. Translation: AAB29451.1.
X77458 Genomic DNA. Translation: CAA54606.1.
AL939117 Genomic DNA. Translation: CAD55329.1.
PIRiJN0830.
RefSeqiNP_733614.1. NC_003888.3.
WP_003975268.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAD55329; CAD55329; CAD55329.
GeneIDi1099107.
KEGGisco:SCO3671.
PATRICi23737092. VBIStrCoe124346_3729.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L46700 Genomic DNA. Translation: AAB29451.1.
X77458 Genomic DNA. Translation: CAA54606.1.
AL939117 Genomic DNA. Translation: CAD55329.1.
PIRiJN0830.
RefSeqiNP_733614.1. NC_003888.3.
WP_003975268.1. NC_003888.3.

3D structure databases

ProteinModelPortaliQ05558.
SMRiQ05558. Positions 1-505.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi100226.SCO3671.

Proteomic databases

PRIDEiQ05558.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD55329; CAD55329; CAD55329.
GeneIDi1099107.
KEGGisco:SCO3671.
PATRICi23737092. VBIStrCoe124346_3729.

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
InParanoidiQ05558.
KOiK04043.
OMAiEKMAPPQ.
OrthoDBiPOG091H01UE.
PhylomeDBiQ05558.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNAK_STRCO
AccessioniPrimary (citable) accession number: Q05558
Secondary accession number(s): Q9KYQ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: September 7, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.