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Q05534

- PHOG_EMENI

UniProt

Q05534 - PHOG_EMENI

Protein

Protein pacG

Gene

pacG

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 3 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    Transcription factor that acts as a positive regulator of nonrepressible acid phosphatase activity. Is a major regulator of responses to nitrogen and carbon starvation and is essential for the expression of genes involved in vegetative incompatibility (like pin-c, het-6, and tol). Vegetative incompatibility is a non-self-recognition system ubiquitous in filamentous fungi which results in programmed cell death By similarity.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi79 – 326248NDT80PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. response to starvation Source: ASPGD
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein pacG
    Alternative name(s):
    Nonrepressible acid phosphatase regulator pacG
    Gene namesi
    Name:pacG
    ORF Names:AN1414
    OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
    Taxonomic identifieri227321 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000000560: Chromosome VII

    Subcellular locationi

    Nucleus. Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 566566Protein pacGPRO_0000023977Add
    BLAST

    Proteomic databases

    PRIDEiQ05534.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 NDT80 DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG79465.
    HOGENOMiHOG000157088.
    OrthoDBiEOG74J9HJ.

    Family and domain databases

    Gene3Di2.60.40.1390. 1 hit.
    InterProiIPR024061. NDT80_DNA-bd_dom.
    IPR008967. p53-like_TF_DNA-bd.
    [Graphical view]
    PfamiPF05224. NDT80_PhoG. 1 hit.
    [Graphical view]
    SUPFAMiSSF49417. SSF49417. 1 hit.
    PROSITEiPS51517. NDT80. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q05534-1 [UniParc]FASTAAdd to Basket

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    MEGFDTMALP YLASPLSLGN MQGTDYLNAL QGMDLPDQRS NFDSETFVSG    50
    DDLTFAHLSP QTLKRFSSGY EDSFPEMVTS FDPPPPAEPP ADSSIDHNNK 100
    LLSFSMPVYP WTLLDYSFRR ASISISAQLH GMFFLAESPW TTSPTENAPP 150
    QQGAELTCYR RNLFQITGSV TLPRALRYII TDTGDRIPIV AHELTVSATE 200
    SVEGNSVKII SVPWKTPAAN DAGKDTGNSS NTAAKVEKEP PAIPLDMLTG 250
    QDLDADYATF PIAWKRLQFR VATANNGRRK ELQQHFVVRL RVVATLSTGM 300
    KTPICEVHSG PVIVRGRSPR NFQSRKDLPL SGSAAASRKN AQAAAASNNL 350
    TRTSPSLTDK AKTVVKSSSP ETSSNGVPQQ SPPNWALATN STLPPPTTTT 400
    LPHSSVYSQS SPEFSRPVEA HRRTTSAIAA PINLSLLDDD SLNLSNGDSR 450
    PHTSFSNDLA SKSLSVDSGR PVKMRKVSHS MPQAQSRSTS ATFLNTANFQ 500
    QMLPVPFTSE SADVLYEYFP LGLEDWQGPV DAVYRPHVVH HTNMPQMKYI 550
    TARGQSKRYF AAEDVF 566
    Length:566
    Mass (Da):61,871
    Last modified:November 16, 2011 - v3
    Checksum:i9BC5AB22BCDC665E
    GO

    Sequence cautioni

    The sequence CBF84810.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence EAA64544.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti376 – 3761G → R in AAA33289. (PubMed:7916713)Curated
    Sequence conflicti423 – 4231R → L in AAA33289. (PubMed:7916713)Curated
    Sequence conflicti447 – 4471G → C in AAA33289. (PubMed:7916713)Curated
    Sequence conflicti451 – 4511P → S in AAA33289. (PubMed:7916713)Curated
    Sequence conflicti460 – 4612AS → VV in AAA33289. (PubMed:7916713)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACD01000022 Genomic DNA. Translation: EAA64544.1. Sequence problems.
    BN001307 Genomic DNA. Translation: CBF84810.1. Sequence problems.
    M96993 Genomic DNA. Translation: AAA33289.1.
    PIRiJN0783.
    RefSeqiXP_659018.1. XM_653926.1.

    Genome annotation databases

    EnsemblFungiiCADANIAT00008025; CADANIAP00008025; CADANIAG00008025.
    GeneIDi2875501.
    KEGGiani:AN1414.2.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACD01000022 Genomic DNA. Translation: EAA64544.1 . Sequence problems.
    BN001307 Genomic DNA. Translation: CBF84810.1 . Sequence problems.
    M96993 Genomic DNA. Translation: AAA33289.1 .
    PIRi JN0783.
    RefSeqi XP_659018.1. XM_653926.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q05534.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADANIAT00008025 ; CADANIAP00008025 ; CADANIAG00008025 .
    GeneIDi 2875501.
    KEGGi ani:AN1414.2.

    Phylogenomic databases

    eggNOGi NOG79465.
    HOGENOMi HOG000157088.
    OrthoDBi EOG74J9HJ.

    Family and domain databases

    Gene3Di 2.60.40.1390. 1 hit.
    InterProi IPR024061. NDT80_DNA-bd_dom.
    IPR008967. p53-like_TF_DNA-bd.
    [Graphical view ]
    Pfami PF05224. NDT80_PhoG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49417. SSF49417. 1 hit.
    PROSITEi PS51517. NDT80. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.
    2. "The 2008 update of the Aspergillus nidulans genome annotation: a community effort."
      Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J., Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M., Estrada C.G.
      , Geysens S., Goldman G., de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B., van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.
      Fungal Genet. Biol. 46:S2-13(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.
    3. "Characterization of an Aspergillus nidulans genomic DNA fragment conferring phosphate-non-repressible acid-phosphatase activity."
      Macrae W.D., Buxton F.P., Sibley S., Garven S., Gwynne D.I., Arst H.N. Jr., Davies R.W.
      Gene 130:247-251(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 132-461.
      Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.

    Entry informationi

    Entry nameiPHOG_EMENI
    AccessioniPrimary (citable) accession number: Q05534
    Secondary accession number(s): C8VM27, Q5BDG6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 88 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Caution

    Was originally thought to be a phosphatase.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3