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Q05534

- PHOG_EMENI

UniProt

Q05534 - PHOG_EMENI

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Protein

Protein pacG

Gene

pacG

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Transcription factor that acts as a positive regulator of nonrepressible acid phosphatase activity. Is a major regulator of responses to nitrogen and carbon starvation and is essential for the expression of genes involved in vegetative incompatibility (like pin-c, het-6, and tol). Vegetative incompatibility is a non-self-recognition system ubiquitous in filamentous fungi which results in programmed cell death (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi79 – 326248NDT80PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. response to starvation Source: ASPGD
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein pacG
Alternative name(s):
Nonrepressible acid phosphatase regulator pacG
Gene namesi
Name:pacG
ORF Names:AN1414
OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Taxonomic identifieri227321 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000000560: Chromosome VII

Subcellular locationi

Nucleus. Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 566566Protein pacGPRO_0000023977Add
BLAST

Proteomic databases

PRIDEiQ05534.

Family & Domainsi

Sequence similaritiesi

Contains 1 NDT80 DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG79465.
HOGENOMiHOG000157088.
InParanoidiQ05534.
OrthoDBiEOG74J9HJ.

Family and domain databases

Gene3Di2.60.40.1390. 1 hit.
InterProiIPR024061. NDT80_DNA-bd_dom.
IPR008967. p53-like_TF_DNA-bd.
[Graphical view]
PfamiPF05224. NDT80_PhoG. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
PROSITEiPS51517. NDT80. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q05534-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEGFDTMALP YLASPLSLGN MQGTDYLNAL QGMDLPDQRS NFDSETFVSG
60 70 80 90 100
DDLTFAHLSP QTLKRFSSGY EDSFPEMVTS FDPPPPAEPP ADSSIDHNNK
110 120 130 140 150
LLSFSMPVYP WTLLDYSFRR ASISISAQLH GMFFLAESPW TTSPTENAPP
160 170 180 190 200
QQGAELTCYR RNLFQITGSV TLPRALRYII TDTGDRIPIV AHELTVSATE
210 220 230 240 250
SVEGNSVKII SVPWKTPAAN DAGKDTGNSS NTAAKVEKEP PAIPLDMLTG
260 270 280 290 300
QDLDADYATF PIAWKRLQFR VATANNGRRK ELQQHFVVRL RVVATLSTGM
310 320 330 340 350
KTPICEVHSG PVIVRGRSPR NFQSRKDLPL SGSAAASRKN AQAAAASNNL
360 370 380 390 400
TRTSPSLTDK AKTVVKSSSP ETSSNGVPQQ SPPNWALATN STLPPPTTTT
410 420 430 440 450
LPHSSVYSQS SPEFSRPVEA HRRTTSAIAA PINLSLLDDD SLNLSNGDSR
460 470 480 490 500
PHTSFSNDLA SKSLSVDSGR PVKMRKVSHS MPQAQSRSTS ATFLNTANFQ
510 520 530 540 550
QMLPVPFTSE SADVLYEYFP LGLEDWQGPV DAVYRPHVVH HTNMPQMKYI
560
TARGQSKRYF AAEDVF
Length:566
Mass (Da):61,871
Last modified:November 16, 2011 - v3
Checksum:i9BC5AB22BCDC665E
GO

Sequence cautioni

The sequence CBF84810.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence EAA64544.1 differs from that shown. Reason: Erroneous gene model prediction.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti376 – 3761G → R in AAA33289. (PubMed:7916713)Curated
Sequence conflicti423 – 4231R → L in AAA33289. (PubMed:7916713)Curated
Sequence conflicti447 – 4471G → C in AAA33289. (PubMed:7916713)Curated
Sequence conflicti451 – 4511P → S in AAA33289. (PubMed:7916713)Curated
Sequence conflicti460 – 4612AS → VV in AAA33289. (PubMed:7916713)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACD01000022 Genomic DNA. Translation: EAA64544.1. Sequence problems.
BN001307 Genomic DNA. Translation: CBF84810.1. Sequence problems.
M96993 Genomic DNA. Translation: AAA33289.1.
PIRiJN0783.
RefSeqiXP_659018.1. XM_653926.1.

Genome annotation databases

EnsemblFungiiCADANIAT00008025; CADANIAP00008025; CADANIAG00008025.
GeneIDi2875501.
KEGGiani:AN1414.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACD01000022 Genomic DNA. Translation: EAA64544.1 . Sequence problems.
BN001307 Genomic DNA. Translation: CBF84810.1 . Sequence problems.
M96993 Genomic DNA. Translation: AAA33289.1 .
PIRi JN0783.
RefSeqi XP_659018.1. XM_653926.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q05534.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADANIAT00008025 ; CADANIAP00008025 ; CADANIAG00008025 .
GeneIDi 2875501.
KEGGi ani:AN1414.2.

Phylogenomic databases

eggNOGi NOG79465.
HOGENOMi HOG000157088.
InParanoidi Q05534.
OrthoDBi EOG74J9HJ.

Family and domain databases

Gene3Di 2.60.40.1390. 1 hit.
InterProi IPR024061. NDT80_DNA-bd_dom.
IPR008967. p53-like_TF_DNA-bd.
[Graphical view ]
Pfami PF05224. NDT80_PhoG. 1 hit.
[Graphical view ]
SUPFAMi SSF49417. SSF49417. 1 hit.
PROSITEi PS51517. NDT80. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.
  2. "The 2008 update of the Aspergillus nidulans genome annotation: a community effort."
    Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J., Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M., Estrada C.G.
    , Geysens S., Goldman G., de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B., van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.
    Fungal Genet. Biol. 46:S2-13(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.
  3. "Characterization of an Aspergillus nidulans genomic DNA fragment conferring phosphate-non-repressible acid-phosphatase activity."
    Macrae W.D., Buxton F.P., Sibley S., Garven S., Gwynne D.I., Arst H.N. Jr., Davies R.W.
    Gene 130:247-251(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 132-461.
    Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.

Entry informationi

Entry nameiPHOG_EMENI
AccessioniPrimary (citable) accession number: Q05534
Secondary accession number(s): C8VM27, Q5BDG6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: November 16, 2011
Last modified: October 29, 2014
This is version 89 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Caution

Was originally thought to be a phosphatase.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3