Reviewed,
UniProtKB/Swiss-Prot Q05534 (PHOG_EMENI)
Last modified
June 16, 2009.
Version 55.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Protein pacG Alternative name(s): Nonrepressible acid phosphatase regulator pacG | ||||
| Gene names |
| ||||
| Organism | Emericella nidulans (Aspergillus nidulans) | ||||
| Taxonomic identifier | 162425 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › Emericella |
Protein attributes
| Sequence length | 351 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Transcription factor that acts as a positive regulator of nonrepressible acid phosphatase activity. Is a major regulator of responses to nitrogen and carbon starvation and is essential for the expression of genes involved in vegetative incompatibility (like pin-c, het-6, and tol). Vegetative incompatibility is a non-self-recognition system ubiquitous in filamentous fungi which results in programmed cell death By similarity. |
| Subcellular location | |
| Sequence similarities | Contains 1 NDT80 domain. |
| Caution | Was originally thought (Ref.2) to be a phosphatase. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Transcription Transcription regulation |
| Cellular component | Cytoplasm Nucleus |
| Gene Ontology (GO) | |
| Biological process | regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcriptionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell nucleusInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | transcription factor activity Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 351 | 351 | Protein pacG | PRO_0000023977 | |||||
Regions | |||||||||
| Domain | 24 – 194 | 171 | NDT80 | ||||||
| DNA binding | 1 – 193 | 193 | By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 245 | 1 | G → R in AAA33289. Ref.2 | ||||||
| Sequence conflict | 292 | 1 | R → L in AAA33289. Ref.2 | ||||||
| Sequence conflict | 316 | 1 | G → C in AAA33289. Ref.2 | ||||||
| Sequence conflict | 320 | 1 | P → S in AAA33289. Ref.2 | ||||||
| Sequence conflict | 329 – 330 | 2 | AH → VV in AAA33289. Ref.2 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae." Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S., Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V., Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S., Braus G.H. Birren B.W.Nature 438:1105-1115(2005) [PubMed: 16372000] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: FGSC 4. |
| [2] | "Characterization of an Aspergillus nidulans genomic DNA fragment conferring phosphate-non-repressible acid-phosphatase activity." Macrae W.D., Buxton F.P., Sibley S., Garven S., Gwynne D.I., Arst H.N. Jr., Davies R.W. Gene 130:247-251(1993) [PubMed: 7916713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-330. Strain: FGSC 4. |
Cross-references
Sequence databases | |
|---|---|
| AACD01000022 Genomic DNA. Translation: EAA64544.1. M96993 Genomic DNA. Translation: AAA33289.1. | |
| PIR | JN0783. |
| RefSeq | XP_659018.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2875501. |
| KEGG | ani:AN1414.2. |
Enzyme and pathway databases | |
| BRENDA | 3.1.3.2. 3859. |
Family and domain databases | |
| InterPro | IPR007888. NDT80_DNA_bd. [Graphical view] |
| Pfam | PF05224. NDT80_PhoG. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PHOG_EMENI | ||||||||
| Accession | Primary (citable) accession number: Q05534 Secondary accession number(s): Q5BDG6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||

Clusters with


