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Protein

Protein pacG

Gene

pacG

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transcription factor that acts as a positive regulator of nonrepressible acid phosphatase activity. Is a major regulator of responses to nitrogen and carbon starvation and is essential for the expression of genes involved in vegetative incompatibility (like pin-c, het-6, and tol). Vegetative incompatibility is a non-self-recognition system ubiquitous in filamentous fungi which results in programmed cell death (By similarity).By similarity

Caution

Was originally thought to be a phosphatase.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi79 – 326NDT80PROSITE-ProRule annotationAdd BLAST248

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein pacG
Alternative name(s):
Nonrepressible acid phosphatase regulator pacG
Gene namesi
Name:pacG
ORF Names:AN1414
OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Taxonomic identifieri227321 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000000560 Componenti: Chromosome VII
  • UP000005890 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000239771 – 566Protein pacGAdd BLAST566

Proteomic databases

PRIDEiQ05534

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000157088
InParanoidiQ05534
OrthoDBiEOG092C3Q5X

Family and domain databases

InterProiView protein in InterPro
IPR024061 NDT80_DNA-bd_dom
IPR008967 p53-like_TF_DNA-bd
PfamiView protein in Pfam
PF05224 NDT80_PhoG, 1 hit
SUPFAMiSSF49417 SSF49417, 1 hit
PROSITEiView protein in PROSITE
PS51517 NDT80, 1 hit

Sequencei

Sequence statusi: Complete.

Q05534-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGFDTMALP YLASPLSLGN MQGTDYLNAL QGMDLPDQRS NFDSETFVSG
60 70 80 90 100
DDLTFAHLSP QTLKRFSSGY EDSFPEMVTS FDPPPPAEPP ADSSIDHNNK
110 120 130 140 150
LLSFSMPVYP WTLLDYSFRR ASISISAQLH GMFFLAESPW TTSPTENAPP
160 170 180 190 200
QQGAELTCYR RNLFQITGSV TLPRALRYII TDTGDRIPIV AHELTVSATE
210 220 230 240 250
SVEGNSVKII SVPWKTPAAN DAGKDTGNSS NTAAKVEKEP PAIPLDMLTG
260 270 280 290 300
QDLDADYATF PIAWKRLQFR VATANNGRRK ELQQHFVVRL RVVATLSTGM
310 320 330 340 350
KTPICEVHSG PVIVRGRSPR NFQSRKDLPL SGSAAASRKN AQAAAASNNL
360 370 380 390 400
TRTSPSLTDK AKTVVKSSSP ETSSNGVPQQ SPPNWALATN STLPPPTTTT
410 420 430 440 450
LPHSSVYSQS SPEFSRPVEA HRRTTSAIAA PINLSLLDDD SLNLSNGDSR
460 470 480 490 500
PHTSFSNDLA SKSLSVDSGR PVKMRKVSHS MPQAQSRSTS ATFLNTANFQ
510 520 530 540 550
QMLPVPFTSE SADVLYEYFP LGLEDWQGPV DAVYRPHVVH HTNMPQMKYI
560
TARGQSKRYF AAEDVF
Length:566
Mass (Da):61,871
Last modified:November 16, 2011 - v3
Checksum:i9BC5AB22BCDC665E
GO

Sequence cautioni

The sequence CBF84810 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence EAA64544 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti376G → R in AAA33289 (PubMed:7916713).Curated1
Sequence conflicti423R → L in AAA33289 (PubMed:7916713).Curated1
Sequence conflicti447G → C in AAA33289 (PubMed:7916713).Curated1
Sequence conflicti451P → S in AAA33289 (PubMed:7916713).Curated1
Sequence conflicti460 – 461AS → VV in AAA33289 (PubMed:7916713).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACD01000022 Genomic DNA Translation: EAA64544.1 Sequence problems.
BN001307 Genomic DNA Translation: CBF84810.1 Sequence problems.
M96993 Genomic DNA Translation: AAA33289.1
PIRiJN0783
RefSeqiXP_659018.1, XM_653926.1

Genome annotation databases

EnsemblFungiiCADANIAT00008025; CADANIAP00008025; CADANIAG00008025
EAA64544; EAA64544; AN1414.2
GeneIDi2875501
KEGGiani:AN1414.2

Similar proteinsi

Entry informationi

Entry nameiPHOG_EMENI
AccessioniPrimary (citable) accession number: Q05534
Secondary accession number(s): C8VM27, Q5BDG6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: November 16, 2011
Last modified: March 28, 2018
This is version 105 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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