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Protein
Submitted name:

Class one outer membrane protein

Gene

porA

Organism
Neisseria meningitidis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

PorinUniRule annotation

Keywords - Biological processi

Ion transport, Transport

Protein family/group databases

TCDBi1.B.1.5.2. the general bacterial porin (gbp) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Class one outer membrane proteinImported
Gene namesi
Name:porAImported
OrganismiNeisseria meningitidisImported
Taxonomic identifieri487 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Subcellular locationi

  • Cell outer membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membraneUniRule annotation, Membrane

Interactioni

Subunit structurei

Homotrimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ05520.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Gram-negative porin family.UniRule annotation

Keywords - Domaini

Transmembrane

Family and domain databases

Gene3Di2.40.160.10. 1 hit.
InterProiIPR023614. Porin_dom.
IPR001702. Porin_Gram-ve.
IPR013793. Porin_Gram-ve_CS.
IPR002299. Porin_Neis.
[Graphical view]
PfamiPF00267. Porin_1. 1 hit.
[Graphical view]
PRINTSiPR00182. ECOLNEIPORIN.
PR00184. NEISSPPORIN.
PROSITEiPS00576. GRAM_NEG_PORIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q05520-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EGRNIQLQLT EPLQNIQQPQ VTKRKSRIRT KISDFGSFIG FKGSEDLGEG
60 70 80 90 100
LKAVWQLEQD VSVAGGGATR WGNRESFVGL AGEFGTLRAG RVANQFDDAS
110 120 130 140 150
KAIDPWDSNN VVASQLGIFK RHDDMPVSVR YDSPEFSGFS GSVQFVPAQN
160 170 180 190 200
SKSAYTPAHF VQQTPESQPT LVPAVVGKPG SDVYYAGLNY KNGGFAGNYA
210 220 230 240 250
FKYAKHANVG RDAFELFLLG SGSDEAKGTD PLKNHQVHRL TGGYEEGGLN
260 270 280 290 300
LALAAQLDLS ENADKTKNST TEIAATASYR FGNAVPRISY AHGFDFIERG
310 320 330 340
KKGENTSYDQ IIAGVDYDFS KRTSAIVSGA WLKRNTGIGN YTQINAAS
Length:348
Mass (Da):37,684
Last modified:July 5, 2004 - v2
Checksum:i5BE62034F74E942B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei348 – 3481Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57180 Genomic DNA. Translation: CAA40467.1.
PIRiS15170.
S18770.
S26753.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57180 Genomic DNA. Translation: CAA40467.1.
PIRiS15170.
S18770.
S26753.

3D structure databases

ProteinModelPortaliQ05520.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

TCDBi1.B.1.5.2. the general bacterial porin (gbp) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.40.160.10. 1 hit.
InterProiIPR023614. Porin_dom.
IPR001702. Porin_Gram-ve.
IPR013793. Porin_Gram-ve_CS.
IPR002299. Porin_Neis.
[Graphical view]
PfamiPF00267. Porin_1. 1 hit.
[Graphical view]
PRINTSiPR00182. ECOLNEIPORIN.
PR00184. NEISSPPORIN.
PROSITEiPS00576. GRAM_NEG_PORIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Topology of outer membrane porins in pathogenic Neisseria spp."
    Van Der Ley P.A., Heckels J.E., Virji M., Hoogerhout P., Poolman J.T.
    Infect. Immun. 59:2963-2971(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Comparison of the class 1 outer membrane proteins of eight serological reference strains of Neisseria meningitidis."
    Maiden M.C., Suker J., McKenna A.J., Bygraves J.A., Feavers I.M.
    Mol. Microbiol. 5:727-736(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2996Imported.
  3. "The porA gene in serogroup A meningococci: evolutionary stability and mechanism of genetic variation."
    Suker J., Feavers I.M., Achtman M., Morelli G., Wang J.F., Maiden M.C.
    Mol. Microbiol. 12:253-265(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ05520_NEIME
AccessioniPrimary (citable) accession number: Q05520
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: July 5, 2004
Last modified: April 29, 2015
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.