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Protein

ATP synthase subunit alpha

Gene

atpA

Organism
Synechococcus sp. (strain PCC 6716)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei364Required for activityUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi171 – 178ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processATP synthesis, Hydrogen ion transport, Ion transport, Transport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alphaUniRule annotation (EC:3.6.3.14UniRule annotation)
Alternative name(s):
ATP synthase F1 sector subunit alphaUniRule annotation
F-ATPase subunit alphaUniRule annotation
Gene namesi
Name:atpAUniRule annotation
OrganismiSynechococcus sp. (strain PCC 6716)
Taxonomic identifieri32048 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus

Subcellular locationi

  • Cellular thylakoid membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CF(1), Membrane, Thylakoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001443602 – 503ATP synthase subunit alphaAdd BLAST502

Proteomic databases

PRIDEiQ05372

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has four main subunits: a1, b1, b'1 and c(9-12) (By similarity).By similarity

Structurei

3D structure databases

ProteinModelPortaliQ05372
SMRiQ05372
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Family and domain databases

CDDicd01132 F1_ATPase_alpha, 1 hit
Gene3Di1.20.150.20, 1 hit
2.40.30.20, 1 hit
HAMAPiMF_01346 ATP_synth_alpha_bact, 1 hit
InterProiView protein in InterPro
IPR023366 ATP_synth_asu-like_sf
IPR000793 ATP_synth_asu_C
IPR038376 ATP_synth_asu_C_sf
IPR033732 ATP_synth_F1_a
IPR005294 ATP_synth_F1_asu
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF00306 ATP-synt_ab_C, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
PIRSFiPIRSF039088 F_ATPase_subunit_alpha, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00962 atpA, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q05372-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSIRPDEIS SIIRQQIEQY EQSINVDNVG TVLQVGDGIA RVYGLDKVMA
60 70 80 90 100
SELVEFEDGT VGIALNLEED NVGVVLMGAG LGIEEGSTVR ATGKIASVPV
110 120 130 140 150
GEAVIGRVVD ALMRPIDGKG EIHATATRLL ESPAPGIVQR KSVCEPLQTG
160 170 180 190 200
ITAIDAMIPI GRGQRELIIG DRQTGKTAVA IDTILNQKGQ DVICVYVAIG
210 220 230 240 250
QKASSVAQVV NVLRERGALD YTIVVAANAS DPAALQYLAP YTGASIAEYF
260 270 280 290 300
MYQGKHTLVI YDDLSKQAQA YRQMSLLLRR PPGREAYPGD VFYLHSRLLE
310 320 330 340 350
RAAKLNDALG GGSMTALPIV ETQAGDVSAY IPTNVISITD GQIFLSSDLF
360 370 380 390 400
NAGLRPAINA GISVSRVGSA AQIKAMKQVA GKLKLELAQF DELQAFAQFA
410 420 430 440 450
SDLDKATQNQ LARGQRLREI LKQPQYSPIP VEYQVATIYA GTNGYLDDIP
460 470 480 490 500
VEAVAKFVAG LRDYLATSKP QYGEAVRSSQ KLDETAEALL KEAIAEYKAG

FTA
Length:503
Mass (Da):53,904
Last modified:January 23, 2007 - v4
Checksum:i3380D46BB8EE728B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X70431 Genomic DNA Translation: CAA49875.1

Similar proteinsi

Entry informationi

Entry nameiATPA_SYNP1
AccessioniPrimary (citable) accession number: Q05372
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 113 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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