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Reviewed, UniProtKB/Swiss-Prot Q05359 (ERP1_YEAST)

Last modified November 24, 2009. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Protein ERP1
Gene names
Name: ERP1
Ordered Locus Names: YAR002C-A
ORF Names: YAR002A
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

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Protein attributes

Sequence length219 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Function

Involved in vesicular protein trafficking.

Subunit structure

Associates with EMP24, ERV25 and ERP2.

Subcellular location

Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Miscellaneous

Present with 20700 molecules/cell in log phase SD medium. Ref.5

Sequence similarities

Belongs to the EMP24/GP25L family.

Contains 1 GOLD domain.

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Binary interactions

With

Entry

#Exp.

IntAct

Notes

itself1EBI-6581,EBI-6581
P386941EBI-6581,EBI-24511
P388451EBI-6581,EBI-24770
Q121441EBI-6581,EBI-37691
AGP1P253761EBI-6581,EBI-2357
ALG5P403501EBI-6581,EBI-2470
ARF1P110761EBI-6581,EBI-2816
AYR1P404711EBI-6581,EBI-25213
CAN1P048171EBI-6581,EBI-3993
CBR1P386261EBI-6581,EBI-2048224
CHO1P084561EBI-6581,EBI-14055
CPT1P178981EBI-6581,EBI-2050738
ELO1P395401EBI-6581,EBI-2049096
ELO2P253581EBI-6581,EBI-6415
EMC2P471331EBI-6581,EBI-25568
EPT1P221401EBI-6581,EBI-6494
ERG1P324761EBI-6581,EBI-6545
ERG11P106141EBI-6581,EBI-5127
ERG25P530451EBI-6581,EBI-6506
ERG26P531991EBI-6581,EBI-6514
ERG5P547811EBI-6581,EBI-6563
ERP2P397041EBI-6581,EBI-6587
ERP3Q124031EBI-6581,EBI-6593
ERP4Q124501EBI-6581,EBI-6598
ERV25P548371EBI-6581,EBI-6642
ERV29P533371EBI-6581,EBI-23662
GAP1P191451EBI-6581,EBI-7314
GNP1P488131EBI-6581,EBI-7758
GOT1Q035541EBI-6581,EBI-2057821
GRX2P176951EBI-6581,EBI-7699
GSF2Q046971EBI-6581,EBI-27807
GWT1P470261EBI-6581,EBI-25989
ICE2P404991EBI-6581,EBI-25109
IST2P382501EBI-6581,EBI-21520
KRE27P405401EBI-6581,EBI-24977
ORM1P532241EBI-6581,EBI-12592
ORM2Q061441EBI-6581,EBI-34916
OST1P415431EBI-6581,EBI-12651
PHO84P252971EBI-6581,EBI-13320
PHO88P382641EBI-6581,EBI-13350
PHS1P408571EBI-6581,EBI-26003
PIS1P061971EBI-6581,EBI-13458
PKR1Q038801EBI-6581,EBI-27252
PMP2P409751EBI-6581,EBI-2043041
PMP3P872841EBI-6581,EBI-13555
PMR1P135861EBI-6581,EBI-3091
PMT7Q066441EBI-6581,EBI-13600
RET2P436211EBI-6581,EBI-4876
RPB11P389021EBI-6581,EBI-15806
RTN1Q049471EBI-6581,EBI-38020
SAC1P323681EBI-6581,EBI-16210
SAM3Q089861EBI-6581,EBI-2056826
SCS7Q035291EBI-6581,EBI-16747
SEC63P149061EBI-6581,EBI-16636
SEY1Q992871EBI-6581,EBI-37523
SPC1P469651EBI-6581,EBI-17823
SPF1P399861EBI-6581,EBI-3128
SSH1P383531EBI-6581,EBI-18175
STE24P471541EBI-6581,EBI-18298
SUR2P389921EBI-6581,EBI-18574
SVP26P388691EBI-6581,EBI-24844
SWP1Q027951EBI-6581,EBI-12666
TNA1P533221EBI-6581,EBI-2051164
UBP1P250371EBI-6581,EBI-19819
UIP4Q089261EBI-6581,EBI-2044051
VHS3Q084381EBI-6581,EBI-30482
VMA21P418061EBI-6581,EBI-20323
WBP1P337671EBI-6581,EBI-12658
YDR476CQ033621EBI-6581,EBI-2057915
YER053C-AQ3E7B01EBI-6581,EBI-2047907
YET1P357231EBI-6581,EBI-26730
YOP1Q124021EBI-6581,EBI-37092

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Ref.4
Chain23 – 219197Protein ERP1
PRO_0000010408

Regions

Topological domain23 – 186164Lumenal Potential
Transmembrane187 – 20721 Potential
Topological domain208 – 21912Cytoplasmic Potential
Domain32 – 131100GOLD

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Sequences

Sequence LengthMass (Da)Tools
Q05359-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 16236C1886FC42E8

FASTA21924,723
        10         20         30         40         50         60 
MLLTSLLQVF ACCLVLPAQV TAFYYYTSGA ERKCFHKELS KGTLFQATYK AQIYDDQLQN 

        70         80         90        100        110        120 
YRDAGAQDFG VLIDIEETFD DNHLVVHQKG SASGDLTFLA SDSGEHKICI QPEAGGWLIK 

       130        140        150        160        170        180 
AKTKIDVEFQ VGSDEKLDSK GKATIDILHA KVNVLNSKIG EIRREQKLMR DREATFRDAS 

       190        200        210 
EAVNSRAMWW IVIQLIVLAV TCGWQMKHLG KFFVKQKIL

« Hide

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References

« Hide 'large scale' references
[1]"Sequencing of chromosome I of Saccharomyces cerevisiae: analysis of the 42 kbp SPO7-CENI-CDC15 region."
Clark M.W., Keng T., Storms R.K., Zhong W.-W., Fortin N., Zeng B., Delaney S., Ouellette B.F.F., Barton A.B., Kaback D.B., Bussey H.
Yeast 10:535-541(1994) [PubMed: 7941740] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]"The nucleotide sequence of chromosome I from Saccharomyces cerevisiae."
Bussey H., Kaback D.B., Zhong W.-W., Vo D.H., Clark M.W., Fortin N., Hall J., Ouellette B.F.F., Keng T., Barton A.B., Su Y., Davies C.J., Storms R.K.
Proc. Natl. Acad. Sci. U.S.A. 92:3809-3813(1995) [PubMed: 7731988] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[3]"Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex."
Marzioch M., Henthorn D.C., Herrmann J.M., Wilson R., Thomas D.Y., Bergeron J.J.M., Solari R.C., Rowley A.
Mol. Biol. Cell 10:1923-1938(1999) [PubMed: 10359606] [Abstract]
Cited for: CHARACTERIZATION.
[4]"Proteins in the early Golgi compartment of Saccharomyces cerevisiae immunoisolated by Sed5p."
Cho J.-H., Noda Y., Yoda K.
FEBS Lett. 469:151-154(2000) [PubMed: 10713261] [Abstract]
Cited for: PROTEIN SEQUENCE OF 23-27, SUBCELLULAR LOCATION.
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

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Cross-references

Sequence databases

L22015 Genomic DNA. Translation: AAC04958.1.
PIRS70311.
RefSeqNP_009402.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

IntActQ05359. 98 interactions.
STRINGQ05359.

Proteomic databases

PeptideAtlasQ05359.

Genome annotation databases

EnsemblYAR002C-A; YAR002C-A; YAR002C-A; Saccharomyces cerevisiae. [Genome view]
GeneID851264.
KEGGsce:YAR002C-A.
NMPDRfig|4932.3.peg.86.

Organism-specific databases

CYGDYAR002c-a.
SGDS000002129. ERP1.

Phylogenomic databases

HOGENOMQ05359.
OMAGSSHEDE
OrthoDBEOG970W0M

Gene expression databases

ArrayExpressQ05359.
GenevestigatorQ05359.
GermOnlineYAR002C-A. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR000348. Emp24_gp25L_p24.
IPR009038. GOLD.
[Graphical view]
PfamPF01105. EMP24_GP25L. 1 hit.
[Graphical view]
PROSITEPS50866. GOLD. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio968228.

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Entry information

Entry nameERP1_YEAST
AccessionPrimary (citable) accession number: Q05359
Entry history
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: November 1, 1996
Last modified: November 24, 2009
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome I

Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents