Q052L0 (Q052L0_LEPBL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
dTDP-glucose 4,6-dehydratase RuleBase RU004473
EC=4.2.1.46 RuleBase RU004473

Gene names

Name:	rmlB EMBL ABJ78735.1
Ordered Locus Names:	LBL_1237 EMBL ABJ78735.1

Organism

Leptospira borgpetersenii serovar Hardjo-bovis (strain L550) [Complete proteome] [HAMAP] EMBL ABJ78735.1

Taxonomic identifier

355276 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Leptospiraceae › Leptospira › Leptospira borgpetersenii › Leptospira borgpetersenii serovar Hardjo-bovis

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. RuleBase RU004473
Cofactor	NAD By similarity. RuleBase RU004473
Sequence similarities	Belongs to the sugar epimerase family. dTDP-glucose dehydratase subfamily. RuleBase RU004473

Ontologies

Keywords
Molecular function	Lyase RuleBase RU004473
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nucleotide-sugar metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	coenzyme binding Inferred from electronic annotation. Source: InterPro dTDP-glucose 4,6-dehydratase activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q052L0 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: C3E22F5EB0381C4C	FASTA	349	40,413
	10 20 30 40 50 60 MKKILVTGGA GFIGSNFVNL ILNENEEYQI IVFDKLTYAG NLKSLEYWKK DPRFIFIKAD 70 80 90 100 110 120 IANKENVFSI FQEHNFDYVA HFAAESHVDR SILGPEEFIK TNVLGTFYLL DAARLQWNGS 130 140 150 160 170 180 YEGKKFLHVS TDEVFGTLGD TGYFTEETPY APNSPYSASK AGSDHIVRSY YHTYHMPVVT 190 200 210 220 230 240 TNCSNNYGPY HFPEKLIPLT ILNCLQGKPL PVYGDGKNIR DWLYVKDHCE ALRLALFQGL 250 260 270 280 290 300 PGETYNIGTR NEKKNIDIVN SICSIMDEFH PSGVPHSKLI QYVKDRPGHD FRYAIDPSKI 310 320 330 340 EKELGWKPKF VFESALRETV RWYLDNESWW KEILSGQYKE YYQNQYEKH

References

[1]

"Genome reduction in Leptospira borgpetersenii reflects limited transmission potential." Bulach D.M., Zuerner R.L., Wilson P., Seemann T., McGrath A., Cullen P.A., Davis J., Johnson M., Kuczek E., Alt D.P., Peterson-Burch B., Coppel R.L., Rood J.I., Davies J.K., Adler B. Proc. Natl. Acad. Sci. U.S.A. 103:14560-14565(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: L550 EMBL ABJ78735.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000348 Genomic DNA. Translation: ABJ78735.1.
RefSeq	YP_797668.1. NC_008508.1.
3D structure databases
ProteinModelPortal	Q052L0.
SMR	Q052L0. Positions 1-340.
ModBase	Search...
Protein-protein interaction databases
STRING	355276.LBL_1237.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABJ78735; ABJ78735; LBL_1237.
GeneID	4408716.
KEGG	lbl:LBL_1237.
PATRIC	22366238. VBILepBor75619_1582.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1088.
HOGENOM	HOG000168006.
KO	K01710.
OMA	IQYVKDR.
ProtClustDB	CLSK574006.
Enzyme and pathway databases
BioCyc	LBOR355276:GHUQ-1513-MONOMER.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR005888. dTDP_Gluc_deHydtase. IPR001509. Epimerase_deHydtase. IPR016040. NAD(P)-bd_dom. [Graphical view]
PANTHER	PTHR10366:SF41. PTHR10366:SF41. 1 hit.
Pfam	PF01370. Epimerase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01181. dTDP_gluc_dehyt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q052L0_LEPBL

Accession

Primary (citable) accession number: Q052L0

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)