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Q05205 (PPB_LYSEN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alkaline phosphatase
Short name=APASE
EC=3.1.3.1
Gene names
Name:phoA
OrganismLysobacter enzymogenes
Taxonomic identifier69 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Lysobacter

Protein attributes

Sequence length539 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Subcellular location

Secreted.

Post-translational modification

The C-terminal Pro-sequence may be required for translocation of the phosphatase across the outer membrane.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionHydrolase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionalkaline phosphatase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2929 Potential
Propeptide30 – 148119
PRO_0000023994
Chain149 – 429281Alkaline phosphatase
PRO_0000023995
Propeptide430 – 539110 Potential
PRO_0000023996

Sequences

Sequence LengthMass (Da)Tools
Q05205 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: C51DC38429936C3E

FASTA53956,490
        10         20         30         40         50         60 
MNLSPSRTPI CAALAAALLG AAALAPAHAA QRILQLSEDT THSKPVSAAS ALRGTPLAKA 

        70         80         90        100        110        120 
GAADRVCEAG AKWLRVGFKQ LKLAGYDSLV LTSSGGDKLV FEGQHWNQRS FTTRPLRGEC 

       130        140        150        160        170        180 
VDIQPYFSQP DSAFQLDRYD YSTVALDKAT VVVAGAGDIC DTSGNACQGT SDLIVSINPT 

       190        200        210        220        230        240 
AVFTAGDNAY NSGTLSEYNS RYAPTWGRFK ALTSPSPGNH DYSTTGAKGY FDYFNGSGNQ 

       250        260        270        280        290        300 
TGPAGDRSKG YYSWDVGDWH FVSLNTMSGG TVAQAQIDWL KADLAANTKP CTAAYFHHPL 

       310        320        330        340        350        360 
LSRGSYSGYS QVKPFWDALY AAKADLVLVG HDHNYQRYGK MNPDKAAASD GIRQVLVGTG 

       370        380        390        400        410        420 
GRAFYGISGS HALLEASNDS TFGVLKLTLS ATGYTGDFVP RAGSSYTDHF TGTCNKGSGN 

       430        440        450        460        470        480 
PPTQTLTLNS VRDVTVKSGG SRDNGATLYA DGSDGGQVLR GLMAWNVSSA AGKTLTGAQV 

       490        500        510        520        530 
KLQVSDRSTG TYDLYRAGAA WTEANASYSG VSLGSKIGSV VPSATGAQSI ALNAAGFSW

« Hide

References

[1]"Nucleotide sequence and characterization of the gene for secreted alkaline phosphatase from Lysobacter enzymogenes."
Au S., Roy K.L., von Tigerstrom R.G.
J. Bacteriol. 173:4551-4557(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 149-179; 267-277 AND 341-361.
Strain: ATCC 29487 / DSM 2043 / LMG 8762 / UASM 495 / VKM B-2235.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X56656 Genomic DNA. Translation: CAA39978.1.
PIRA42467.

3D structure databases

ProteinModelPortalQ05205.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004843. Metallo_PEstase_dom.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePPB_LYSEN
AccessionPrimary (citable) accession number: Q05205
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 3, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
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