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Protein

Probable transaldolase

Gene

tal

Organism
Leptospira borgpetersenii serovar Hardjo-bovis (strain L550)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei83Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:LBL_1551
OrganismiLeptospira borgpetersenii serovar Hardjo-bovis (strain L550)
Taxonomic identifieri355276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001263261 – 214Probable transaldolaseAdd BLAST214

Structurei

3D structure databases

ProteinModelPortaliQ051I1
SMRiQ051I1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 3B subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CW3 Bacteria
COG0176 LUCA
HOGENOMiHOG000226073
KOiK00616
OMAiVRHPMHV
OrthoDBiPOG091H04ZO

Family and domain databases

CDDicd00956 Transaldolase_FSA, 1 hit
Gene3Di3.20.20.701 hit
HAMAPiMF_00494 Transaldolase_3b, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR001585 TAL/FSA
IPR022999 Transaldolase_3B
IPR004731 Transaldolase_3B/F6P_aldolase
IPR018225 Transaldolase_AS
IPR033919 TSA/FSA_arc/bac
PANTHERiPTHR10683 PTHR10683, 2 hits
PfamiView protein in Pfam
PF00923 TAL_FSA, 1 hit
TIGRFAMsiTIGR00875 fsa_talC_mipB, 1 hit
PROSITEiView protein in PROSITE
PS01054 TRANSALDOLASE_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q051I1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELYLDTANI DEIKEIASYG LVDGVTTNPS IIAKSGRNFR EVIKEICSIV
60 70 80 90 100
SGPVSAEVLS TKFDGMMKEA LELVEIAENV VIKVPLIPEG LKTVVELTKR
110 120 130 140 150
NIPTNVTLCF SSSQALLAAK AGATYISPFI GRVDDTSWDG MELISEIREI
160 170 180 190 200
YDNYGYDTRI LAASIRGPMH LKESALRGAD CATMPHSAFL QLFKHPLTDI
210
GLEKFLEDSK KLKW
Length:214
Mass (Da):23,599
Last modified:November 14, 2006 - v1
Checksum:iEBD8AAAE2166A331
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000348 Genomic DNA Translation: ABJ79014.1
RefSeqiWP_002633037.1, NC_008508.1

Genome annotation databases

EnsemblBacteriaiABJ79014; ABJ79014; LBL_1551
GeneIDi4408265
KEGGilbl:LBL_1551

Similar proteinsi

Entry informationi

Entry nameiTAL_LEPBL
AccessioniPrimary (citable) accession number: Q051I1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 14, 2006
Last modified: October 25, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program