Skip Header

 
Contribute Send feedback
Read comments (1) or add your own

Reviewed, UniProtKB/Swiss-Prot Q05185 (PHT5_PSEPU)

Last modified January 20, 2009. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    4,5-dihydroxyphthalate decarboxylase
      Short name=DHP decarboxylase
    EC=4.1.1.55
Gene names
Name: pht5
Encoded onPlasmid PHT
OrganismPseudomonas putida
Taxonomic identifier303 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Catalytic activity

4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2.

Pathway

Xenobiotic degradation; phtalic acid degradation; 3,4-dihydroxybenzoate from phtalic acid: step 3/3.

Induction

Induced by phthalate and repressed by glucose.

Sequence similarities

To P.testosteroni DHP decarboxylase.

Ontologies

Keywords
   Biological processAromatic hydrocarbons catabolism
   Molecular functionDecarboxylase
Lyase
   Technical termPlasmid
Gene Ontology (GO)
   Biological processaromatic compound catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular function4,5-dihydroxyphthalate decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2582584,5-dihydroxyphthalate decarboxylase
PRO_0000058410

Sequences

Sequence LengthMass (Da)Tools
Q05185-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 575CEDAA43D31AE6

FASTA25828,580
        10         20         30         40         50         60 
MAREPIIMNK LNLSIAVGNY VRIRPLVDGE VQIDGVDPIF MLQDPEEIFF RAFRHADYDI 

        70         80         90        100        110        120 
CELSLSSYSV KTAAGTSPYI AVPVFPSRAF RHTSIYIRND RGIESAADLK GKRIGVPEYQ 

       130        140        150        160        170        180 
LTANVWVRLF LEEDHGLKAS DVTWVRGGYE ETGRLEKIVL KLPADVIVEN APETETLSGM 

       190        200        210        220        230        240 
LASGELDAVI GPRAPSCFTQ GHPKVSYLYR DPQGAASDWY RALSYSRSCT CWGSGARWPS 

       250 
STLGYPGPLP KHSRSPSP 

« Hide

References

[1]"Genes in PHT plasmid encoding the initial degradation pathway of phthalate in Pseudomonas putida."
Nomura Y., Nakagawa M., Ogawa N., Harashima S., Oshima Y.
J. Ferment. Bioeng. 74:333-344(1992)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: NMH102-2.

Cross-references

Sequence databases

D13229 Genomic DNA. Translation: BAA02513.1.

3D structure databases

ModBaseSearch...

Enzyme and pathway databases

BRENDA4.1.1.55. 403.

Family and domain databases

ProtoNetSearch...

Entry information

Entry namePHT5_PSEPU
AccessionPrimary (citable) accession number: Q05185
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: January 20, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents