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Q05185 (PHT5_PSEPU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 31, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4,5-dihydroxyphthalate decarboxylase

Short name=DHP decarboxylase
EC=4.1.1.55
Gene names
Name:pht5
Encoded onPlasmid PHT
OrganismPseudomonas putida (Arthrobacter siderocapsulatus)
Taxonomic identifier303 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2.

Pathway

Xenobiotic degradation; phthalate degradation; 3,4-dihydroxybenzoate from phthalate: step 3/3.

Induction

Induced by phthalate and repressed by glucose.

Sequence similarities

To P.testosteroni DHP decarboxylase.

Ontologies

Keywords
   Biological processAromatic hydrocarbons catabolism
   Molecular functionDecarboxylase
Lyase
   Technical termPlasmid
Gene Ontology (GO)
   Biological processaromatic compound catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular function4,5-dihydroxyphthalate decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2582584,5-dihydroxyphthalate decarboxylase
PRO_0000058410

Sequences

Sequence LengthMass (Da)Tools
Q05185 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 575CEDAA43D31AE6

FASTA25828,580
        10         20         30         40         50         60 
MAREPIIMNK LNLSIAVGNY VRIRPLVDGE VQIDGVDPIF MLQDPEEIFF RAFRHADYDI 

        70         80         90        100        110        120 
CELSLSSYSV KTAAGTSPYI AVPVFPSRAF RHTSIYIRND RGIESAADLK GKRIGVPEYQ 

       130        140        150        160        170        180 
LTANVWVRLF LEEDHGLKAS DVTWVRGGYE ETGRLEKIVL KLPADVIVEN APETETLSGM 

       190        200        210        220        230        240 
LASGELDAVI GPRAPSCFTQ GHPKVSYLYR DPQGAASDWY RALSYSRSCT CWGSGARWPS 

       250 
STLGYPGPLP KHSRSPSP 

« Hide

References

[1]"Genes in PHT plasmid encoding the initial degradation pathway of phthalate in Pseudomonas putida."
Nomura Y., Nakagawa M., Ogawa N., Harashima S., Oshima Y.
J. Ferment. Bioeng. 74:333-344(1992)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: NMH102-2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D13229 Genomic DNA. Translation: BAA02513.1.

3D structure databases

ProteinModelPortalQ05185.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR015168. NMT1.
[Graphical view]
PfamPF09084. NMT1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePHT5_PSEPU
AccessionPrimary (citable) accession number: Q05185
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: May 31, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways