Reviewed, UniProtKB/Swiss-Prot Q05185 (PHT5_PSEPU)

Names and origin

Protein names

Recommended name:
    4,5-dihydroxyphthalate decarboxylase
      Short name=DHP decarboxylase
    EC=4.1.1.55

Gene names

Name:

pht5

Encoded on

Plasmid PHT

Organism

Pseudomonas putida

Taxonomic identifier

303 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	258 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2.
Pathway	Xenobiotic degradation; phtalic acid degradation; 3,4-dihydroxybenzoate from phtalic acid: step 3/3.
Induction	Induced by phthalate and repressed by glucose.
Sequence similarities	To P.testosteroni DHP decarboxylase.

Ontologies

Keywords
Biological process	Aromatic hydrocarbons catabolism
Molecular function	Decarboxylase Lyase
Technical term	Plasmid
Gene Ontology (GO)
Biological process	aromatic compound catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	4,5-dihydroxyphthalate decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 258	258	4,5-dihydroxyphthalate decarboxylase		PRO_0000058410

Sequences

	Sequence		Length	Mass (Da)
	Q05185-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 575CEDAA43D31AE6	FASTA	258	28,580
	10 20 30 40 50 60 MAREPIIMNK LNLSIAVGNY VRIRPLVDGE VQIDGVDPIF MLQDPEEIFF RAFRHADYDI 70 80 90 100 110 120 CELSLSSYSV KTAAGTSPYI AVPVFPSRAF RHTSIYIRND RGIESAADLK GKRIGVPEYQ 130 140 150 160 170 180 LTANVWVRLF LEEDHGLKAS DVTWVRGGYE ETGRLEKIVL KLPADVIVEN APETETLSGM 190 200 210 220 230 240 LASGELDAVI GPRAPSCFTQ GHPKVSYLYR DPQGAASDWY RALSYSRSCT CWGSGARWPS 250 STLGYPGPLP KHSRSPSP

References

[1]	"Genes in PHT plasmid encoding the initial degradation pathway of phthalate in Pseudomonas putida." Nomura Y., Nakagawa M., Ogawa N., Harashima S., Oshima Y. J. Ferment. Bioeng. 74:333-344(1992) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: NMH102-2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D13229 Genomic DNA. Translation: BAA02513.1.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	4.1.1.55. 403.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

PHT5_PSEPU

Accession

Primary (citable) accession number: Q05185

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	November 1, 1996
Last modified:	January 20, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)