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Protein

Brain acid soluble protein 1

Gene

Basp1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Calmodulin-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Brain acid soluble protein 1
Alternative name(s):
22 kDa neuronal tissue-enriched acidic protein
Neuronal axonal membrane protein NAP-22
Gene namesi
Name:Basp1
Synonyms:Nap22
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi621491. Basp1.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB
  • growth cone Source: UniProtKB-SubCell
  • nuclear speck Source: UniProtKB
  • nucleus Source: UniProtKB
  • plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cell projection, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 220219Brain acid soluble protein 1PRO_0000142897Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi2 – 21N-myristoyl glycine1 Publication
Modified residuei31 – 311PhosphothreonineBy similarity
Modified residuei36 – 361PhosphothreonineBy similarity
Modified residuei40 – 401PhosphoserineBy similarity
Modified residuei91 – 911PhosphoserineCombined sources
Modified residuei127 – 1271PhosphoserineCombined sources
Modified residuei130 – 1301PhosphoserineCombined sources
Modified residuei158 – 1581PhosphoserineBy similarity
Modified residuei165 – 1651PhosphoserineBy similarity
Modified residuei167 – 1671PhosphoserineBy similarity
Modified residuei170 – 1701PhosphoserineBy similarity
Modified residuei189 – 1891PhosphoserineBy similarity

Keywords - PTMi

Lipoprotein, Myristate, Phosphoprotein

Proteomic databases

PRIDEiQ05175.

PTM databases

iPTMnetiQ05175.
PhosphoSiteiQ05175.

Expressioni

Tissue specificityi

Brain.

Interactioni

Protein-protein interaction databases

BioGridi248987. 3 interactions.

Family & Domainsi

Sequence similaritiesi

Belongs to the BASP1 family.Curated

Phylogenomic databases

HOGENOMiHOG000095176.
InParanoidiQ05175.
KOiK17272.

Family and domain databases

InterProiIPR008408. BASP1.
[Graphical view]
PANTHERiPTHR23212. PTHR23212. 1 hit.
PfamiPF05466. BASP1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q05175-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSKLSKKKK GYNVNDEKAK DKDKKAEGAG TEEEGTQKES EPQAAADATE
60 70 80 90 100
VKESAEEKPK DAADGEAKAE EKEADKAAAK EEAPKAEPEK SEGAAEEQPE
110 120 130 140 150
PAPAPEQEAA APGPAAGGEA PKAGEASAES TGAADGAPQE EGEAKKTEAP
160 170 180 190 200
AAGPEAKSDA APAASDSKPS TEPAPSSKET PAASEAPSSA AKAPAPAAPA
210 220
AEPQAEAPVA SSEQSVAVKE
Length:220
Mass (Da):21,790
Last modified:January 23, 2007 - v2
Checksum:iED7C9401EDB89147
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D14441 mRNA. Translation: BAA03333.1.
PIRiA46597.
RefSeqiNP_071636.1. NM_022300.1.
UniGeneiRn.37779.

Genome annotation databases

GeneIDi64160.
KEGGirno:64160.
UCSCiRGD:621491. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D14441 mRNA. Translation: BAA03333.1.
PIRiA46597.
RefSeqiNP_071636.1. NM_022300.1.
UniGeneiRn.37779.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi248987. 3 interactions.

PTM databases

iPTMnetiQ05175.
PhosphoSiteiQ05175.

Proteomic databases

PRIDEiQ05175.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi64160.
KEGGirno:64160.
UCSCiRGD:621491. rat.

Organism-specific databases

CTDi10409.
RGDi621491. Basp1.

Phylogenomic databases

HOGENOMiHOG000095176.
InParanoidiQ05175.
KOiK17272.

Miscellaneous databases

NextBioi612806.
PROiQ05175.

Family and domain databases

InterProiIPR008408. BASP1.
[Graphical view]
PANTHERiPTHR23212. PTHR23212. 1 hit.
PfamiPF05466. BASP1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Purification and molecular cloning of a novel acidic calmodulin binding protein from rat brain."
    Maekawa S., Maekawa M., Hattori S., Nakamura S.
    J. Biol. Chem. 268:13703-13709(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
    Tissue: Brain.
  2. Lubec G., Chen W.-Q., Kang S.U., Lubec S.
    Submitted (SEP-2007) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 11-18; 39-52; 91-157 AND 179-220, IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: Sprague-Dawley.
    Tissue: Brain and Hippocampus.
  3. "The BASP1 family of myristoylated proteins abundant in axonal termini. Primary structure analysis and physico-chemical properties."
    Mosevitsky M.I., Capony J.-P., Skladchikova G.Y.U., Novitskaya V.A., Plekhanov A.Y.U., Zakharov V.V.
    Biochimie 79:373-384(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: PARTIAL PROTEIN SEQUENCE.
    Tissue: Brain.
  4. "Expression and myristoylation of NAP-22 using a baculovirus transfer vector system."
    Maekawa S., Matsuura Y., Nakaruma S.
    Biochim. Biophys. Acta 1218:119-122(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: MYRISTOYLATION AT GLY-2.
  5. "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-91; SER-127 AND SER-130, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiBASP1_RAT
AccessioniPrimary (citable) accession number: Q05175
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: January 23, 2007
Last modified: January 20, 2016
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.