ID   AMDA_BORBR              Reviewed;         240 AA.
AC   Q05115;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-MAR-2009, entry version 36.
DE   RecName: Full=Arylmalonate decarboxylase;
DE            Short=AMDase;
DE            EC=4.1.1.76;
OS   Bordetella bronchiseptica (Alcaligenes bronchisepticus).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=518;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-10.
RC   STRAIN=KU 1201;
RX   MEDLINE=93152143; PubMed=1369144; DOI=10.1007/BF00174474;
RA   Miyamoto K., Ohta H.;
RT   "Cloning and heterologous expression of a novel arylmalonate
RT   decarboxylase gene from Alcaligenes bronchisepticus KU 1201.";
RL   Appl. Microbiol. Biotechnol. 38:234-238(1992).
CC   -!- CATALYTIC ACTIVITY: 2-aryl-2-methylmalonate = 2-arylpropanoate +
CC       CO(2).
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DR   EMBL; S54007; AAC60426.1; -; Genomic_DNA.
DR   EMBL; D13116; BAA02419.1; -; Genomic_DNA.
DR   PIR; A48374; JS0754.
DR   PDB; 2VLB; X-ray; 1.92 A; A/B/C/D=1-240.
DR   PDB; 3DG9; X-ray; 1.50 A; A=1-240.
DR   PDBsum; 2VLB; -.
DR   PDBsum; 3DG9; -.
DR   GO; GO:0047436; F:arylmalonate decarboxylase activity; IEA:EC.
DR   InterPro; IPR015942; Asp/Glu/hydantoin_racemase.
DR   Pfam; PF01177; Asp_Glu_race; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Decarboxylase; Direct protein sequencing; Lyase.
FT   CHAIN         1    240       Arylmalonate decarboxylase.
FT                                /FTId=PRO_0000064576.
FT   STRAND        8     15
FT   HELIX        22     25
FT   STRAND       33     37
FT   HELIX        48     65
FT   STRAND       67     72
FT   HELIX        75     79
FT   HELIX        83     97
FT   STRAND      101    103
FT   HELIX       104    114
FT   STRAND      119    126
FT   HELIX       128    140
FT   STRAND      144    150
FT   HELIX       154    157
FT   HELIX       164    177
FT   STRAND      182    188
FT   HELIX       196    204
FT   STRAND      208    210
FT   HELIX       211    223
FT   HELIX       235    238
SQ   SEQUENCE   240 AA;  24735 MW;  2514373725BDAA7F CRC64;
     MQQASTPTIG MIVPPAAGLV PADGARLYPD LPFIASGLGL GSVTPEGYDA VIESVVDHAR
     RLQKQGAAVV SLMGTSLSFY RGAAFNAALT VAMREATGLP CTTMSTAVLN GLRALGVRRV
     ALATAYIDDV NERLAAFLAE ESLVPTGCRS LGITGVEAMA RVDTATLVDL CVRAFEAAPD
     SDGILLSCGG LLTLDAIPEV ERRLGVPVVS SSPAGFWDAV RLAGGGAKAR PGYGRLFDES
//