Q05115 (AMDA_BORBO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Arylmalonate decarboxylase Short name=AMDase EC=4.1.1.76
Organism	Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Taxonomic identifier	518 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity

2-aryl-2-methylmalonate = 2-arylpropanoate + CO2.

Ontologies

Keywords
Molecular function	Decarboxylase Lyase
Technical term	3D-structure Direct protein sequencing
Gene Ontology (GO)
Biological_process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	arylmalonate decarboxylase activity Inferred from electronic annotation. Source: EC racemase activity, acting on amino acids and derivatives Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 240

240

Arylmalonate decarboxylase

PRO_0000064576

Secondary structure

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240

Helix Strand Turn

Details...

Beta strand

8 – 15

8

Helix

23 – 27

5

Beta strand

33 – 37

5

Helix

45 – 51

7

Helix

52 – 54

3

Helix

55 – 64

10

Beta strand

67 – 72

6

Helix

75 – 79

5

Helix

83 – 97

15

Beta strand

101 – 103

3

Helix

104 – 114

11

Beta strand

118 – 126

9

Helix

128 – 140

13

Beta strand

144 – 150

7

Helix

156 – 160

5

Helix

164 – 176

13

Beta strand

182 – 187

6

Helix

196 – 204

9

Beta strand

208 – 210

3

Helix

211 – 222

12

Beta strand

231 – 233

3

Helix

235 – 238

4

Sequences

	Sequence		Length	Mass (Da)
	Q05115 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 2514373725BDAA7F	FASTA	240	24,735
	10 20 30 40 50 60 MQQASTPTIG MIVPPAAGLV PADGARLYPD LPFIASGLGL GSVTPEGYDA VIESVVDHAR 70 80 90 100 110 120 RLQKQGAAVV SLMGTSLSFY RGAAFNAALT VAMREATGLP CTTMSTAVLN GLRALGVRRV 130 140 150 160 170 180 ALATAYIDDV NERLAAFLAE ESLVPTGCRS LGITGVEAMA RVDTATLVDL CVRAFEAAPD 190 200 210 220 230 240 SDGILLSCGG LLTLDAIPEV ERRLGVPVVS SSPAGFWDAV RLAGGGAKAR PGYGRLFDES

References

[1]	"Cloning and heterologous expression of a novel arylmalonate decarboxylase gene from Alcaligenes bronchisepticus KU 1201." Miyamoto K., Ohta H. Appl. Microbiol. Biotechnol. 38:234-238(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-10. Strain: KU 1201.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

S54007 Genomic DNA. Translation: AAC60426.1.
D13116 Genomic DNA. Translation: BAA02419.1.

PIR

JS0754. A48374.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2VLB	X-ray	1.92	A/B/C/D	1-240	[»]
3DG9	X-ray	1.50	A	1-240	[»]
3DTV	X-ray	2.10	A/B/C/D	1-240	[»]
3EIS	X-ray	2.10	A/B/C/D	1-240	[»]
3IP8	X-ray	1.50	A	1-240	[»]
3IXL	X-ray	1.45	A	1-240	[»]
3IXM	X-ray	1.90	A	1-240	[»]

ProteinModelPortal

Q05115.

SMR

Q05115. Positions 6-240.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR026286. AMDase.
IPR015942. Asp/Glu/hydantoin_racemase.
[Graphical view]

Pfam

PF01177. Asp_Glu_race. 1 hit.
[Graphical view]

PIRSF

PIRSF015736. MI. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

Q05115.

Entry information

Entry name

AMDA_BORBO

Accession

Primary (citable) accession number: Q05115

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	April 3, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program