Reviewed, UniProtKB/Swiss-Prot Q05115 (AMDA_BORBR)

Names and origin

Protein names	Recommended name:     Arylmalonate decarboxylase       Short name=AMDase     EC=4.1.1.76
Organism	Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Taxonomic identifier	518 [NCBI]
Taxonomic lineage	Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity

2-aryl-2-methylmalonate = 2-arylpropanoate + CO2.

Ontologies

Keywords
Molecular function	Decarboxylase Lyase
Technical term	3D-structure Direct protein sequencing
Gene Ontology (GO)
Molecular function	arylmalonate decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 240

240

Arylmalonate decarboxylase

PRO_0000064576

Secondary structure

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240

Helix Strand Turn

Details...

Beta strand

8 – 15

8

Helix

22 – 25

4

Beta strand

33 – 37

5

Helix

48 – 65

18

Beta strand

67 – 72

6

Helix

75 – 79

5

Helix

83 – 97

15

Beta strand

101 – 103

3

Helix

104 – 114

11

Beta strand

119 – 126

8

Helix

128 – 140

13

Beta strand

144 – 150

7

Helix

154 – 157

4

Helix

164 – 177

14

Beta strand

182 – 188

7

Helix

196 – 204

9

Beta strand

208 – 210

3

Helix

211 – 223

13

Helix

235 – 238

4

Sequences

	Sequence		Length	Mass (Da)
	Q05115-1 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 2514373725BDAA7F	FASTA	240	24,735
	10 20 30 40 50 60 MQQASTPTIG MIVPPAAGLV PADGARLYPD LPFIASGLGL GSVTPEGYDA VIESVVDHAR 70 80 90 100 110 120 RLQKQGAAVV SLMGTSLSFY RGAAFNAALT VAMREATGLP CTTMSTAVLN GLRALGVRRV 130 140 150 160 170 180 ALATAYIDDV NERLAAFLAE ESLVPTGCRS LGITGVEAMA RVDTATLVDL CVRAFEAAPD 190 200 210 220 230 240 SDGILLSCGG LLTLDAIPEV ERRLGVPVVS SSPAGFWDAV RLAGGGAKAR PGYGRLFDES

References

[1]	"Cloning and heterologous expression of a novel arylmalonate decarboxylase gene from Alcaligenes bronchisepticus KU 1201." Miyamoto K., Ohta H. Appl. Microbiol. Biotechnol. 38:234-238(1992) [PubMed: 1369144] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-10. Strain: KU 1201.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

S54007 Genomic DNA. Translation: AAC60426.1.
D13116 Genomic DNA. Translation: BAA02419.1.

PIR

JS0754. A48374.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2VLB	X-ray	1.92	A/B/C/D	1-240	[»]
3DG9	X-ray	1.50	A	1-240	[»]

ModBase

Search...

Family and domain databases

InterPro

IPR015942. Asp/Glu/hydantoin_racemase.
[Graphical view]

Pfam

PF01177. Asp_Glu_race. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

AMDA_BORBR

Accession

Primary (citable) accession number: Q05115

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	March 3, 2009
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)