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Protein

Ferric enterobactin receptor

Gene

pfeA

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Specific receptor for the siderophore ferric enterobactin.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Ion transport, Iron transport, Transport

Keywords - Ligandi

Iron

Protein family/group databases

TCDBi1.B.14.1.5. the outer membrane receptor (omr) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Ferric enterobactin receptor
Gene namesi
Name:pfeA
Ordered Locus Names:PA2688
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA2688.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000003476926 – 746Ferric enterobactin receptorAdd BLAST721

Proteomic databases

PaxDbiQ05098.
PRIDEiQ05098.

Expressioni

Inductioni

By iron and enterobactin.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA2688.

Structurei

3D structure databases

ProteinModelPortaliQ05098.
SMRiQ05098.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi39 – 44TonB box6
Motifi729 – 746TonB C-terminal boxAdd BLAST18

Sequence similaritiesi

Belongs to the TonB-dependent receptor family.Curated

Keywords - Domaini

Signal, TonB box, Transmembrane, Transmembrane beta strand

Phylogenomic databases

eggNOGiENOG4107RNH. Bacteria.
COG4771. LUCA.
HOGENOMiHOG000276827.
InParanoidiQ05098.
KOiK19611.
OMAiAIYQWEN.
PhylomeDBiQ05098.

Family and domain databases

Gene3Di2.170.130.10. 1 hit.
2.40.170.20. 1 hit.
InterProiIPR012910. Plug_dom.
IPR000531. TonB-dep_rcpt_b-brl.
IPR010917. TonB_rcpt_CS.
IPR010105. TonB_sidphr_rcpt.
[Graphical view]
PfamiPF07715. Plug. 1 hit.
PF00593. TonB_dep_Rec. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01783. TonB-siderophor. 1 hit.
PROSITEiPS01156. TONB_DEPENDENT_REC_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q05098-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSRALPAVP FLLLSSCLLA NAVHAAGQGD GSVIELGEQT VVATAQEETK
60 70 80 90 100
QAPGVSIITA EDIAKRPPSN DLSQIIRTMP GVNLTGNSSS GQRGNNRQID
110 120 130 140 150
IRGMGPENTL ILVDGKPVSS RNSVRYGWRG ERDSRGDTNW VPADQVERIE
160 170 180 190 200
VIRGPAAARY GNGAAGGVVN IITKQAGAET HGNLSVYSNF PQHKAEGASE
210 220 230 240 250
RMSFGLNGPL TENLSYRVYG NIAKTDSDDW DINAGHESNR TGKQAGTLPA
260 270 280 290 300
GREGVRNKDI DGLLSWRLTP EQTLEFEAGF SRQGNIYTGD TQNTNSNNYV
310 320 330 340 350
KQMLGHETNR MYRETYSVTH RGEWDFGSSL AYLQYEKTRN SRINEGLAGG
360 370 380 390 400
TEGIFDPNNA GFYTATLRDL TAHGEVNLPL HLGYEQTLTL GSEWTEQKLD
410 420 430 440 450
DPSSNTQNTE EGGSIPGLAG KNRSSSSSAR IFSLFAEDNI ELMPGTMLTP
460 470 480 490 500
GLRWDHHDIV GDNWSPSLNL SHALTERVTL KAGIARAYKA PNLYQLNPDY
510 520 530 540 550
LLYSRGQGCY GQSTSCYLRG NDGLKAETSV NKELGIEYSH DGLVAGLTYF
560 570 580 590 600
RNDYKNKIES GLSPVDHASG GKGDYANAAI YQWENVPKAV VEGLEGTLTL
610 620 630 640 650
PLADGLKWSN NLTYMLQSKN KETGDVLSVT PRYTLNSMLD WQATDDLSLQ
660 670 680 690 700
ATVTWYGKQK PKKYDYHGDR VTGSANDQLS PYAIAGLGGT YRLSKNLSLG
710 720 730 740
AGVDNLFDKR LFRAGNAQGV VGIDGAGAAT YNEPGRTFYT SLTASF
Length:746
Mass (Da):80,968
Last modified:June 1, 1994 - v1
Checksum:iADD4FB0CB22C3251
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M98033 Genomic DNA. Translation: AAA25928.1.
AE004091 Genomic DNA. Translation: AAG06076.1.
PIRiA40636.
RefSeqiNP_251378.1. NC_002516.2.
WP_003113404.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG06076; AAG06076; PA2688.
GeneIDi882784.
KEGGipae:PA2688.
PATRICi19839875. VBIPseAer58763_2813.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M98033 Genomic DNA. Translation: AAA25928.1.
AE004091 Genomic DNA. Translation: AAG06076.1.
PIRiA40636.
RefSeqiNP_251378.1. NC_002516.2.
WP_003113404.1. NC_002516.2.

3D structure databases

ProteinModelPortaliQ05098.
SMRiQ05098.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA2688.

Protein family/group databases

TCDBi1.B.14.1.5. the outer membrane receptor (omr) family.

Proteomic databases

PaxDbiQ05098.
PRIDEiQ05098.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG06076; AAG06076; PA2688.
GeneIDi882784.
KEGGipae:PA2688.
PATRICi19839875. VBIPseAer58763_2813.

Organism-specific databases

PseudoCAPiPA2688.

Phylogenomic databases

eggNOGiENOG4107RNH. Bacteria.
COG4771. LUCA.
HOGENOMiHOG000276827.
InParanoidiQ05098.
KOiK19611.
OMAiAIYQWEN.
PhylomeDBiQ05098.

Family and domain databases

Gene3Di2.170.130.10. 1 hit.
2.40.170.20. 1 hit.
InterProiIPR012910. Plug_dom.
IPR000531. TonB-dep_rcpt_b-brl.
IPR010917. TonB_rcpt_CS.
IPR010105. TonB_sidphr_rcpt.
[Graphical view]
PfamiPF07715. Plug. 1 hit.
PF00593. TonB_dep_Rec. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01783. TonB-siderophor. 1 hit.
PROSITEiPS01156. TONB_DEPENDENT_REC_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPFEA_PSEAE
AccessioniPrimary (citable) accession number: Q05098
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: November 2, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.