Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Family of serine hydrolases 2

Gene

FSH2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Serine hydrolase of unknown specificity.1 Publication

Miscellaneous

Present with 1070 molecules/cell in log phase SD medium.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei110Charge relay systemBy similarity1
Active sitei174Charge relay systemBy similarity1
Active sitei203Charge relay systemBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Serine esterase

Enzyme and pathway databases

BioCyciYEAST:G3O-32903-MONOMER

Protein family/group databases

ESTHERiyeast-FSH2 FSH1

Names & Taxonomyi

Protein namesi
Recommended name:
Family of serine hydrolases 2 (EC:3.1.-.-)
Gene namesi
Name:FSH2
Ordered Locus Names:YMR222C
ORF Names:YM9959.04C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR222C
SGDiS000004835 FSH2

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002125811 – 223Family of serine hydrolases 2Add BLAST223

Proteomic databases

MaxQBiQ05015
PaxDbiQ05015
PRIDEiQ05015

Interactioni

Protein-protein interaction databases

BioGridi35400, 70 interactors
DIPiDIP-5637N
STRINGi4932.YMR222C

Structurei

3D structure databases

ProteinModelPortaliQ05015
SMRiQ05015
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AB hydrolase 3 family.Curated

Phylogenomic databases

GeneTreeiENSGT00730000113940
HOGENOMiHOG000194266
InParanoidiQ05015
OMAiFRDPTIC
OrthoDBiEOG092C49CE

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR005645 FSH_dom
PfamiView protein in Pfam
PF03959 FSH1, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit

Sequencei

Sequence statusi: Complete.

Q05015-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKNVLMLHG LAQSGDYFAS KTKGFRAEME KLGYKLYYPT APNEFPPADV
60 70 80 90 100
PDFLGEVIAD APGDGENTGV LAWLENDPST GGYFIPQTTI DYLHNYVLEN
110 120 130 140 150
GPFAGIVGFS QGAGVAGYLA TDFNGLLGLT TEEQPPLEFF MAVSGFRFQP
160 170 180 190 200
QQYQEQYDLH PISVPSLHVQ GELDTITEPA KVQGLYNSCT EDSRTLLMHS
210 220
GGHFVPNSRG FVRKVAQWLQ QLT
Length:223
Mass (Da):24,534
Last modified:November 1, 1997 - v1
Checksum:iF7BE3BFCED4EC5B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49939 Genomic DNA Translation: CAA90193.1
BK006946 Genomic DNA Translation: DAA10121.1
PIRiS57590
RefSeqiNP_013949.1, NM_001182729.1

Genome annotation databases

EnsemblFungiiYMR222C; YMR222C; YMR222C
GeneIDi855262
KEGGisce:YMR222C

Similar proteinsi

Entry informationi

Entry nameiFSH2_YEAST
AccessioniPrimary (citable) accession number: Q05015
Secondary accession number(s): D6W047
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 23, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health