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Q05007 (ABDA_ARTSF) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Homeobox protein abdominal-A homolog
Gene names
Name:ABDA
OrganismArtemia franciscana (Brine shrimp) (Artemia sanfranciscana)
Taxonomic identifier6661 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaCrustaceaBranchiopodaAnostracaArtemiidaeArtemia

Protein attributes

Sequence length139 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Function

Required for segmental identity of the second through eighth abdominal segments. Once a pattern of abdA expression is turned on in a given parasegment, it remains on the more posterior parasegment, so that the complex pattern of expression is built up in the successive parasegments. The abdA product appears to repress expression of Ubx whenever they appear in the same cell, but abdA is repressed by AbdB only in the eight and ninth abdominal segments.

Subcellular location

Nucleus Probable.

Sequence similarities

Belongs to the Antp homeobox family.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
   Molecular functionDevelopmental protein
Gene Ontology (GO)
   Biological_processmulticellular organismal development

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 139›139Homeobox protein abdominal-A homolog
PRO_0000200255

Regions

DNA binding6 – 6560Homeobox

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q05007 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 7DF831839E298E32

FASTA13916,311
        10         20         30         40         50         60 
PNGCPRRRGR QTYTRYQTLE LEKEFHFNHY LTRRRRIEIA HALCLTERQI KIWFQNRRMK 

        70         80         90        100        110        120 
LKKELRAVKE INEQARKDRE EQEHKIRSSS SDDGSIGKGV GIPLDASLLK SNDSQSVSLN 

       130 
HLTHKSPDGM MDKTPKSII 

« Hide

References

[1]"HOM/Hox genes of Artemia: implications for the origin of insect and crustacea body plans."
Averof M., Akam M.
Curr. Biol. 3:73-78(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X70076 Genomic DNA. Translation: CAA49681.1.
PIRS31810.

3D structure databases

ProteinModelPortalQ05007.
SMRQ05007. Positions 6-64.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.10.60. 1 hit.
InterProIPR022132. Abdominal-A.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamPF12407. Abdominal-A. 1 hit.
PF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSPR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
PROSITEPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameABDA_ARTSF
AccessionPrimary (citable) accession number: Q05007
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 16, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Vertebrate homeotic Hox proteins

Nomenclature of vertebrate homeotic Hox proteins and list of entries