Q04X69 (DCD_LEPBL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	LBL_3016

Organism

Leptospira borgpetersenii serovar Hardjo-bovis (strain L550) [Complete proteome] [HAMAP]

Taxonomic identifier

355276 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Leptospiraceae › Leptospira › Leptospira borgpetersenii › Leptospira borgpetersenii serovar Hardjo-bovis

Protein attributes

Sequence length	173 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 173	173	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000117978

Sequences

	Sequence		Length	Mass (Da)
	Q04X69 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 5B8427DA0A80D4C2	FASTA	173	19,695
	10 20 30 40 50 60 MILTGKEIQK RIGKDIIITP YSEKQLNPNS YNLRLHEELL IYTELPLDMK KPNLTKKQII 70 80 90 100 110 120 PESGLLLKPG ILYLGRTLEF TETHHLVPML EGRSSIGRLG MLVHVTAGFG DVGFKGFWTL 130 140 150 160 170 EISVIQPLIV YPGVEVCQIF YHTLEGQITE YTSGKYQANQ GIQPSMLYQD FEK

References

[1]

"Genome reduction in Leptospira borgpetersenii reflects limited transmission potential." Bulach D.M., Zuerner R.L., Wilson P., Seemann T., McGrath A., Cullen P.A., Davis J., Johnson M., Kuczek E., Alt D.P., Peterson-Burch B., Coppel R.L., Rood J.I., Davies J.K., Adler B. Proc. Natl. Acad. Sci. U.S.A. 103:14560-14565(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: L550.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000348 Genomic DNA. Translation: ABJ80326.1.
RefSeq	YP_799259.1. NC_008508.1.
3D structure databases
ProteinModelPortal	Q04X69.
ModBase	Search...
Protein-protein interaction databases
STRING	355276.LBL_3016.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABJ80326; ABJ80326; LBL_3016.
GeneID	4405966.
KEGG	lbl:LBL_3016.
PATRIC	22370900. VBILepBor75619_3893.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	GIDIHAT.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	LBOR355276:GHUQ-3253-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_LEPBL

Accession

Primary (citable) accession number: Q04X69

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	November 14, 2006
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program